• HIV infection 

Danavir R 600 Tablet Tablet is an antiviral combination of medicine that belongs to the category of protease inhibitors. The protease enzyme forms the final protein structure of the HIV. Darunavir and Ritonavir work by inhibiting the action of protease enzymes and leads to the formation of HIV proteins with poor morphology. This, in turn, stops the replication of the virus.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Danavir R 600 Tablet and reduce its effectiveness by causing undesirable side effects.

• Do not store Danavir R 600 Tablet above 25°C
• Protect the medicine from light and excessive moisture.
• Keep the medicine out of reach of children and pets
• If you forgot to take the tablet, take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

It is an orally available prescription drug. Your doctor will decide the dose and duration of Danavir R 600 Tablet based on the disease condition and other factors such as body weight and age. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with a glass of water. 

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious 

• Heart problems
• Severe skin reactions
• Pancreatitis
• Increased risk of bleeding
• Liver problems
• Diabetes

Common 

• Skin rash
• Nausea, vomiting
• Swelling in the face and body
• Abdominal pain, diarrhea
• Back pain
• Dizziness
• Cough, pain in throat.

Discuss effective contraception methods with your doctor, along with fertility concerns. Danavir R 600 Tablet might reduce its effectiveness in contraception; alternative methods of non-hormonal contraception are recommended. Do not stop the medicine until your doctor advises. Regular blood tests are recommended to evaluate your liver function and hepatitis B virus level. Notify your doctor if you experience any serious side effects. You are doctor may change your dose or stop the treatment. 

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. your doctor has prescribed at the right time of day and in the correct order. Do not stop using your medicine unless your doctor tells you to. Your immune system may get stronger when you start taking HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

1. Janssen Pharmaceuticals, [Revised on Apr 2022] [Accessed on 20th May 2023], https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/PREZISTA-pi.pdf
2. AbbVie Corporation, [Revised on 5th Jul 2021] [Accessed on 20th May 2023], https://www.abbvie.ca/content/dam/abbvie-dotcom/ca/en/documents/products/NORVIR_PM_EN.pdf
3. KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
4. Capetti et al., A dual regimen of ritonavir/darunavir plus dolutegravir for rescue or simplification of rescue therapy: 48 weeks’ observational data, BMC Infectious Diseases (2017) 17:658, https://bmcinfectdis.biomedcentral.com/counter/pdf/10.1186/s12879-017-2755-4.pdf