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Embremma 0.5mg Injection is a chemotherapy drug that contains the active substance eribulin, which belongs to the class of antineoplastic agents. Embremma 0.5mg Injection is used in adults for advanced breast cancer or liposarcoma (a type of cancer originating from fat tissue) when other treatments have stopped working.

It is not recommended to take Embremma 0.5mg Injection if you are allergic to Eribulin or any of its other ingredients. Consult your doctor if you believe this applies to you. It is not recommended for children and adolescents younger than 18 years since the effects of Embremma 0.5mg Injection in this population are unknown. Before starting the treatment, you should inform your physician if you have fever, infections, liver, or heart problems. Before starting the treatment, give a detailed account of your medical history and medications.

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Advanced breast cancer
Liposarcoma

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Eribulin stops the growth and spread of cancer cells, specifically targeting the growth phase of microtubules, which are structures that help cells divide. It prevents them from growing without interfering with their shrinking phase. Additionally, it causes tubulin, a protein essential for cell division, to clump together in a way that disrupts cell division. This ultimately leads to the blockage of the cell cycle (G2/M phase), disrupting the formation of structures necessary for cell division (mitotic spindles) and triggering cell death through apoptosis.

"}},{"id":"48c65149-971e-407e-ac50-e818fb83bb2c","type":"PARA","position":4,"content_placement":1,"data":{"heading":"Interaction of Embremma 0.5mg Injection with other drugs","text":"

Inform your doctor about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Embremma 0.5mg Injection and reduce effectiveness by causing undesirable side effects.

"}},{"id":"0e5ef212-0986-4294-bad5-00e12916765b","type":"PARA","position":5,"content_placement":1,"data":{"heading":"More Information about Embremma 0.5mg Injection","text":"

Store Embremma 0.5mg Injection at 25°C.
Keep it in its original packaging.
Protect it from light and moisture.
Keep it out of the reach of children and pets.

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Embremma 0.5mg Injection will be given to you by your healthcare provider. It is injected directly into a vein (intravenous infusion) in a cycle. Your healthcare provider determines the dose, duration, and frequency based on your age, body weight, and severity of your condition. If you forget or miss your Embremma 0.5mg Injection cycle dose, make another appointment as soon as possible. Do not wait until your next planned visit. Do not stop the treatment without physician advice.

"}},{"id":"c89a1991-4be4-4107-93ae-720667f5814a","type":"SAFETY_ADVICE","position":7,"content_placement":2,"data":{"heading":"Safety Advice for Embremma 0.5mg Injection","safety_list":[{"id":"1f33e5a8-83f7-4ac6-9ecc-dcc0f9dbb037","advice":"Breast Feeding","tag":"unsafe","description":"

Embremma 0.5mg Injection is not recommended while breastfeeding since it is unknown whether it passes through breast milk. Inform your doctor if you are breastfeeding or planning to breastfeed before starting the treatment with Embremma 0.5mg Injection.

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Embremma 0.5mg Injection contains small amounts of alcohol. Hence, it is generally recommended that patients taking Embremma 0.5mg Injection avoid or limit their alcohol intake, as alcohol can enhance the risk of liver damage and exacerbate any liver-related side effects of Embremma 0.5mg Injection.

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Embremma 0.5mg Injection can affect the liver's normal functioning, causing abnormalities in liver function tests. Hence, you should inform your healthcare provider if you have pre-existing liver problems before starting this treatment.

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Embremma 0.5mg Injection can cause side effects like blood clots in the lungs and inflammation of the lungs. Inform your doctor if you have ever had lung disorders before starting the treatment, as its symptoms may worsen with Embremma 0.5mg Injection.

","imageUrl":"https://assets.mrmed.in/others/file-1674132427859-226731771-Lungs.jpg"},{"id":"03223e8a-d34f-4fff-bd5a-43452c444ee3","advice":"Driving","tag":"unsafe","description":"

Embremma 0.5mg Injection causes tiredness and dizziness, which may impair your ability to drive, cycle, or operate machinery. Avoid doing so until the treatment.

","imageUrl":"https://assets.mrmed.in/others/file-1674132431331-421990512-Driving.jpg"},{"id":"b048011f-ce37-4210-97c5-b78d50d24e8a","advice":"Pregnancy","tag":"unsafe","description":"

Embremma 0.5mg Injection is unsafe for pregnant women as it may cause fetal harm. Inform your doctor promptly if you are pregnant, planning for pregnancy, or think you may get pregnant before starting the treatment with Embremma 0.5mg Injection.

","imageUrl":"https://assets.mrmed.in/others/file-1674132401469-949914510-Pregnancy.jpg"}]}},{"id":"bac50c99-5dd4-4937-87c7-fda6575a7c88","type":"PARA","position":8,"content_placement":1,"data":{"heading":"Side Effects of Embremma 0.5mg Injection","text":"

Side effects are unwanted symptoms that occur due to medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

Sepsis (severe infection)
Severe allergic reaction
Serious skin conditions (Stevens-Johnson syndrome)

Common

Decrease in the number of white blood cells or red blood cells
Tiredness or weakness
Nausea, vomiting, constipation, diarrhea
Numbness, tingling or prickling sensations
Fever
Loss of appetite, weight loss
Difficulty breathing, cough
Pain in the joints, muscles, and back
Headache
Hair loss

"}},{"id":"5f38c0d4-e02a-4515-a06a-94d7bef8046c","type":"PARA","position":9,"content_placement":1,"data":{"heading":"Word of Advice","text":"$23"}},{"id":"3696eef3-376d-4f44-aea0-ec99a642f18a","type":"FAQ","position":10,"content_placement":2,"data":{"heading":"FAQs about Embremma 0.5mg Injection","faq_list":[{"id":"52052db0-76f4-446a-b9d5-70417514d1a6","question":"

What is the most important information I should know while taking Embremma 0.5mg Injection?

","answer":"

Embremma 0.5mg Injection can cause serious adverse effects such as low white blood cell count, numbness, tingling, and pain in the hands and feet. Inform your physician immediately if you face any of these symptoms.

"},{"id":"dc00af7e-507c-42f7-b93d-5705fc7ed677","question":"

Does Embremma 0.5mg Injection cause infertility?

","answer":"

Yes, Embremma 0.5mg Injection causes infertility in men and women. It is necessary to use effective birth control methods during the treatment and for three weeks (females) and 14 weeks (males) after the final dose of the injection.

"},{"id":"15957808-2087-4cc5-a593-213f53dfe771","question":"

Is hair loss caused by Embremma 0.5mg Injection reversible?

","answer":"

Hair loss is a common side effect of Embremma 0.5mg Injection Injection. It is reversible, but it depends totally on the severity of the hair loss and varies from person to person. Consult your doctor if you have severe hair loss.

"},{"id":"f26d3ce2-19fd-4a7b-832d-2e3f8a29ad38","question":"

Do I have to follow any special dietary requirements while taking Embremma 0.5mg Injection?

","answer":"

It depends upon the severity of the disease condition. You can have a normal diet until your physician tells you to follow any special food or diet chart. Check with your doctor if you have any nutrition concerns.

"},{"id":"f50c830d-ce2a-45d4-9217-db48bec9f726","question":"

What should I do if I miss taking Embremma 0.5mg Injection?

","answer":"

It is important to get the injection at the right time. If you missed your appointment, contact your healthcare provider and schedule your dosing immediately. Keep follow-ups on your next schedule.

"}]}},{"id":"634f6c50-1929-400e-8d28-df295e8bf6b4","type":"PARA","position":11,"content_placement":3,"data":{"heading":"Fact Box of Embremma 0.5mg Injection","text":"

Molecule name: Eribulin

Therapeutic class: Anticancer

Pharmacological class: Monoclonal antibody-drug conjugate

Indications:

1. Advanced breast cancer

2. Liposarcoma

Dosage form: Injections

Habit forming: No

"}},{"id":"395ac8de-c479-4c60-962a-7e4f297c48c3","type":"PARA","position":12,"content_placement":3,"data":{"heading":"References","text":"

Eisai Europe Limited, Electronic medicines compendium (EMC), [Revised on Jan 2023] [Accessed on Feb 2024], https://www.medicines.org.uk/emc/files/pil.4517.pdf
Genentech, Inc, US Food and Drug Administration (FDA), [Revised on Jan 2016], [Accessed on Feb 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/201532s015lbl.pdf
Goodman & Gilman's Pharmacological Basis of Therapeutics, Pharmacotherapy of neoplastic drugs, 13th edition, 2018, 1187.

"}},{"id":"081deb65-175a-4dab-a74d-134f42477507","type":"DISCLAIMER","position":13,"content_placement":5,"data":{"heading":"Disclaimer","text":"

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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