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Gestone 8% Vaginal Gel
Last updated on 30 Jun 2026 | 10:17 AM (IST)
₹148
MRP: ₹182.82
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Introduction
Gestone 8% Vaginal Gel contains the active ingredient Progesterone, a natural hormone essential for maintaining the menstrual cycle, supporting pregnancy, and regulating the female reproductive system. It is primarily produced by the ovaries after ovulation and, during pregnancy, by the placenta. The medication helps balance hormone levels and is often prescribed for conditions related to progesterone deficiency or infertility support.
The Gestone 8% Vaginal Gel dosage should be used exactly as directed by your doctor. Follow the proper Gestone 8% Vaginal Gel administration technique, which usually involves inserting the gel into the vagina using the provided applicator. Always wash your hands before and after application.
Key Gestone 8% Vaginal Gel benefits include supporting early pregnancy, improving implantation success, and regulating menstrual cycles. This medicine should be used only under medical supervision, especially when prescribed for fertility or hormonal therapy.
Proper Gestone 8% Vaginal Gel storage requires keeping it in a cool, dry place away from direct sunlight. Patients can safely Buy Gestone 8% Vaginal Gel online through verified pharmacies. The Gestone 8% Vaginal Gel price may vary by brand and pack size, and Gestone 8% Vaginal Gel substitutes are available if recommended by a physician. Consult your doctor regarding Gestone 8% Vaginal Gel and pregnancy usage for safety and effectiveness.
Uses
Gestone 8% Vaginal Gel uses are in the treatment of the following:
- Hormone replacement therapy: Gestone 8% Vaginal Gel is used along with estrogen to reduce menopausal symptoms.
- Amenorrhea: A condition in which women don’t get their periods for months
- Reduce the risk of uterine cancer
How Gestone 8% Vaginal Gel works
The therapeutic effect of Gestone 8% Vaginal Gel is to regulate and support various reproductive processes in the body, including the menstrual cycle, fertility treatments, hormone replacement therapy, and pregnancy maintenance. It helps prepare the uterus for potential pregnancy, maintains the uterine lining, prevents contractions that could lead to miscarriage, and contributes to overall hormonal balance. It can also be used in contraception to inhibit ovulation, thicken cervical mucus, and create an unfavourable environment for sperm, thus preventing pregnancy.
Interaction of Gestone 8% Vaginal Gel with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Gestone 8% Vaginal Gel, reducing effectiveness by causing undesirable side effects.
Storage conditions
- Stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to use Gestone 8% Vaginal Gel
This injection is given by a healthcare provider. The dosage and frequency will depend on the specific condition being treated.
Safety Advice for Gestone 8% Vaginal Gel
Breast Feeding
Gestone 8% Vaginal Gel may not be recommended while breastfeeding, as it can pass into breast milk and potentially affect the nursing infant.
Alcohol
Combining Gestone 8% Vaginal Gel with alcohol is generally not recommended. Alcohol can increase the sedative effects of this medication and may enhance certain side effects, such as drowsiness, dizziness, and impaired coordination.
Liver
Gestone 8% Vaginal Gel is generally used cautiously in individuals with liver impairment or liver disease. The medication is metabolised in the liver, and impaired liver function can affect the metabolism and clearance of this medication from the body.
Lungs
If you have pre-existing lung conditions or respiratory issues, it's important to inform your healthcare provider before taking Gestone 8% Vaginal Gel.
Driving
Progesterones.NPP can cause side effects that may impair your ability to drive or operate machinery safely. Common side effects are drowsiness, dizziness, and vision changes. These effects can affect your coordination, reaction time, and judgment, making driving unsafe or performing tasks requiring alertness.
Pregnancy
This medicine is safe for pregnancy if prescribed by your doctor.
Side Effects
Gestone 8% Vaginal Gel causes some side effects like all medications, although not everyone will experience them. Gestone 8% Vaginal Gel side effects are
Serious:
- Allergic reaction
- Swelling
- Painful urination
- Vaginal bleeding
- Depression
- Memory loss
- Breast lumps
- Dark patches on the skin
- Vomiting
- Blood clots
Common:
- Nausea
- Bloating
- Vaginal discharge
- Mood swings
- Frequent urination
- Tiredness
Expert Tips
-
Inform your healthcare provider about any existing medical conditions such as liver or kidney impairment, epilepsy, or cardiovascular diseases before starting treatment.
-
Some individuals may develop hypersensitivity reactions to Gestone 8% Vaginal Gel.
-
Seek immediate medical attention if you experience symptoms like rash, itching, swelling, or difficulty breathing.
-
Use this medication with caution if you have a history of cardiovascular disease, arrhythmias, or are taking other medicines that can affect heart rhythm.
-
Pregnant or breastfeeding individuals should consult their doctor before using this medication.
-
Avoid smoking while taking this medicine, as it can increase the risk of blood clots.
FAQs about Gestone 8% Vaginal Gel
Q1.
Can Gestone 8% Vaginal Gel be used for male patients?
While Gestone 8% Vaginal Gel is primarily associated with female reproductive health, it may also have uses in certain male conditions. Your healthcare professional can provide more information on cases where this medication may be prescribed for male patients.
Q2.
What are the common side effects of Gestone 8% Vaginal Gel?
Common side effects of Gestone 8% Vaginal Gel may include fatigue, dizziness, headache, breast tenderness or swelling, bloating, nausea, mood changes, and changes in menstrual bleeding patterns. These side effects are typically mild and transient, and not everyone experiences them.
Q3.
Can Gestone 8% Vaginal Gel affect mood and emotional well-being?
Gestone 8% Vaginal Gel, like any hormone therapy, can potentially impact mood and emotional well-being. While some individuals may experience mood changes or emotional fluctuations while using this medication, others may not. If you have concerns about the effects on your mood or emotional state, discussing them with your healthcare professional is important.
Q4.
Can Gestone 8% Vaginal Gel be used to prevent miscarriages?
Gestone 8% Vaginal Gel is often prescribed to support pregnancy and reduce the risk of miscarriage, particularly in cases of progesterone deficiency or other factors impacting pregnancy viability. Your healthcare professional can evaluate your individual situation and determine if this medication is an appropriate intervention for preventing miscarriages.
Q5.
Can Gestone 8% Vaginal Gel be used for fertility treatment in menopausal women?
Gestone 8% Vaginal Gel is commonly used in fertility treatments, but its use in menopausal women for fertility purposes may vary. Depending on the specific circumstances and underlying causes of infertility, your healthcare professional can guide the potential role of this medication in your fertility treatment plan.
Q6.
Can Gestone 8% Vaginal Gel be used for non-reproductive health conditions?
While Gestone 8% Vaginal Gel is commonly used in reproductive health contexts, emerging studies explore its potential therapeutic applications in various non-reproductive conditions such as neuroprotection, mood disorders, and cardiovascular health. However, the use of this medication for non-reproductive conditions is still being researched, and its efficacy and safety may vary.
Q7.
Can Gestone 8% Vaginal Gel be used for contraception?
Gestone 8% Vaginal Gel can be used as a form of contraception. Discussing contraceptive options with your healthcare professional to determine the most suitable method for you is important.
Fact Box of Gestone 8% Vaginal Gel
|
Molecule name |
Progesterone |
|
Therapeutic class |
Progestins |
|
Pharmacological class |
Progestational agent |
|
Indications
|
1. Gastroparesis 2. Nausea and vomiting 3. Gastroesophageal reflux disease (Acid reflux and heartburn) |
References
- Watson Laboratories Inc, US Food and Drug Administration, [Revised on 2007] [Accessed on 12th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/017362s104lbl.pdf
- MP Warren et al., Use of Progesterone in clinical practice, Int J Fertil Womens Med, 1999, 44(2):96-103. [Accessed on 12th June 2023], https://pubmed.ncbi.nlm.nih.gov/10338267/
- Donald G Stein et al, The case for progesterone, Ann N Y Acad Sci, 2005, 1052:152-69 [Accessed on 12th June 2023], https://pubmed.ncbi.nlm.nih.gov/16024758/
- Edwards M et al., Progestins, NCBI Bookshelf, [Revised on 2020] [Accessed on 12th June 2023], https://www.ncbi.nlm.nih.gov/books/NBK563211/#_NBK563211_pubdet_
- Besins Healthcare (UK) Ltd, Electronic Medicines Compendium (EMC) [Revised on 10 May 2022], [Accessed on 12th June 2023],https://www.medicines.org.uk/emc/product/352/pil#gref
Disclaimer
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Author Details

Written By
Dr. Vijayalakshmi N.
BDS

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 30 Jun 2026 | 10:17 AM (IST)

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