• Hormone replacement therapy: Gufigest Gel is used along with estrogen to reduce menopausal symptoms.

• Amenorrhea: A condition in which women don’t get their periods for months

• Reduce the risk of uterine cancer

The therapeutic effect of Gufigest Gel is to regulate and support various reproductive processes in the body, including the menstrual cycle, fertility treatments, hormone replacement therapy, and pregnancy maintenance. It helps prepare the uterus for potential pregnancy, maintains the uterine lining, prevents contractions that could lead to miscarriage, and contributes to overall hormonal balance. It can also be used in contraception to inhibit ovulation, thicken cervical mucus, and create an unfavourable environment for sperm, thus preventing pregnancy.

Taking Gufigest Gel (progesterone vaginal gel) with any of the following medicines may change the effect of either of them and increase the risk of side effects.

1. Carbamazepine, Phenytoin, or Phenobarbital (Oral Route) Moderate
   Use with caution.
   These medicines may increase the breakdown of progesterone in the body and reduce its effectiveness.

2. Rifampicin (Oral Route) Moderate
   Avoid using together unless advised by a doctor.
   Rifampicin may lower progesterone levels and decrease its therapeutic effect.

3. Ketoconazole or Itraconazole (Oral Route) Moderate
   Use under medical supervision.
   These medicines may increase progesterone levels in the body and raise the risk of side effects.

4. Other hormonal therapies such as Oestrogen products (Oral/Transdermal Route) Moderate
   Use only if prescribed.
   Concomitant use may alter hormonal balance and increase the risk of side effects such as irregular bleeding.

5. Anticoagulants such as Warfarin (Oral Route) Mild
   Use with caution.
   Progesterone may slightly affect blood clotting response, and monitoring may be required.

• Stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F).

• Keep away from moisture, heat, and light.

• It should not be frozen.

• Keep away from children and pets.

Susten SR 400mg Tablet is used orally. The dosage and frequency will depend on the specific condition being treated, as decided by the healthcare provider. 

Gufigest Gel can cause side effects, as with all medications, although not everyone will experience them. 

Serious:

• Allergic reaction

• Swelling

• Painful urination

• Vaginal bleeding

• Depression

• Memory loss

• Breast lumps

• Dark patches on the skin

• Vomiting

• Blood clots

Common:

• Nausea

• Bloating

• Vaginal discharge

• Mood swings

• Frequent urination

• Tiredness

1. Inform your healthcare provider about any existing medical conditions, including liver or kidney problems, epilepsy, or cardiovascular diseases.

2. Some individuals may develop hypersensitivity reactions to Progesterone NPP; seek immediate help if you notice rash, itching, swelling, or breathing difficulty.

3. Use this medication cautiously if you have a history of cardiovascular disease or arrhythmias, or if you are taking medicines that may affect heart rhythm.

4. Pregnant or breastfeeding individuals should consult their doctor before using this medication.

5. Avoid smoking while taking this medicine, as it may increase the risk of blood clots.