All Substitutes


Loading...

Disclaimer

Want to know more?
Read Our Editorial Policy

Did you find this information helpful?

    
GLOBUCEL 5GM INJECTION 100ML_1
GLOBUCEL 5GM INJECTION 100ML_2
GLOBUCEL 5GM INJECTION 100ML_1
18% Off

Globucel 5gm Injection 100ml

Prescription Required

cold-chain

Salt Composition : Human Normal Immunoglobulin

Manufacturer : INTAS PHARMACEUTICALS LTD

Origin of Medicine : India

MRP: 10866.88
Price : 8910
You Save : 1957 (18%)

1 Vial(s) Of 100ml

Prepaid Only. Non-Returnable

Pincode
Delivery By -

Introduction to Globucel 5gm Injection 100ml

Globucel 5gm Injection 100ml is an immunostimulant drug in the category of immunoglobulin derivatives, containing the active ingredient Human Normal Immunoglobulin. It is used as a replacement therapy for individuals with primary immunodeficiency disorders (PIDs), where the body's immune system cannot produce sufficient antibodies to fight off infections. The medication is also used to modulate or regulate the immune system in certain autoimmune and inflammatory conditions. It can help reduce excessive inflammation and suppress abnormal immune responses.

This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Stop taking this tablet and contact your doctor immediately if you develop a rash or skin symptoms. If you have a selective IgA deficiency, there is a risk of developing antibodies against IgA. In such cases, normal human immunoglobulin should be used cautiously or avoided altogether. Inform your physician if you have a history of IgA deficiency. After receiving Globucel 5gm Injection 100ml, it is possible to experience a temporary decrease in the concentration of white blood cells, a condition named as neutropenia (low neutrophil count) which resolves spontaneously within a week.

The administration of normal human immunoglobulin may interfere with the effectiveness of live attenuated vaccines. It is advisable to avoid live vaccines for a certain period after receiving this drug. The overdose of Globucel 5gm Injection 100ml may lead to fluid overload, particularly in patients with pre-existing heart failure or compromised renal function. Patients with such conditions should be carefully monitored during infusion. Inform your doctor of any heart, thyroid, kidney, or liver disease. Your physician may prescribe you a low dose and perform regular blood tests. The use of this medicine during pregnancy or breastfeeding should be discussed with your physician. 


Uses of Globucel 5gm Injection 100ml

  • Treat inflammatory disorders
  • Primary immunodeficiency disease (PID)

Therapeutic Effects of Globucel 5gm Injection 100ml

Globucel 5gm Injection 100ml works by restoring the immunoglobulin G (IgG) antibodies. It directly binds to the Fc fragment-specific receptors and acts against inflammatory mediators. It induces cell death in B and T cells, eventually reducing inflammation and the severity of infections.


Interaction of Globucel 5gm Injection 100ml with other drugs

Inform your physician about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Globucel 5gm Injection 100ml and cause undesirable side effects.


More Information about Globucel 5gm Injection 100ml

  • Store Globucel 5gm Injection 100ml in a refrigerator (2°C- 8°C).
  • Do not freeze.

How to consume Globucel 5gm Injection 100ml

Globucel 5gm Injection 100ml is usually administered through a vein (intravenously) by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. 


Safety Advices for Globucel 5gm Injection 100ml

Image Not Available  

Pregnancy

  

Globucel 5gm Injection 100mls should be taken if it is necessary during pregnancy. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment

Image Not Available  

Breast Feeding

  

Globucel 5gm Injection 100mls should be taken if it is necessary during breastfeeding. Consult your doctor for more advice.

Image Not Available  

Lungs

  

It is unknown whether Globucel 5gm Injection 100ml is safe for patients with lung problems. Contact your doctor if you experience any lung-related symptoms.

Image Not Available  

Liver

  

Inform your doctor if you have liver disease because Globucel 5gm Injection 100ml should be used cautiously with a liver condition.

Image Not Available  

Alcohol

  

It is unknown whether consuming alcohol while taking a Globucel 5gm Injection 100ml is safe. Please speak with your physician.

Image Not Available  

Driving

  

Driving vehicles or operating machinery while taking Globucel 5gm Injection 100ml is unsafe because it may cause a lack of coordination and concentration. 


Side Effects of Globucel 5gm Injection 100ml

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.

Serious

  • Severe allergic reaction (rash, itching, swelling of lips, tongue, wheezing, difficulty breathing, low blood pressure with confusion, dizziness, fainting)
  • Meningitis (inflammation of the brain)
  • Respiratory failure
  • Migraine
  • High blood pressure
  • Blood clot in lungs
  • Rupturing of red blood cells

Common

  • Rash
  • Itching
  • Wheezing
  • Difficulty in breathing
  • Swelling of the eyelids
  • Fever
  • Confusion
  • Dizziness
  • Low BP

Word of Advice

If you have a current or past history of a kidney disorder, it is important to inform your physician. They will exercise caution and closely monitor your kidney function during treatment with Globucel 5gm Injection 100ml. Eat a well-balanced diet. You should avoid driving or handling machines if you feel dizzy or tired. Do not touch or rub your skin after injecting this medicine. Wear loose-fitting clothing to avoid discomfort.


FAQs

Q 1. How long does it take for Globucel 5gm Injection 100ml to work?

It usually takes 30 to 60 minutes of administration for Globucel 5gm Injection 100ml to start working.

Q 2. How is Globucel 5gm Injection 100ml administered?

Globucel 5gm Injection 100ml is available as a solution for injection, intended for intravenous administration. Your healthcare provider will calculate the accurate dose and duration of this treatment based on your condition and administer this medication as an intravenous infusion.

Q 3. What should you not take with Globucel 5gm Injection 100ml?

Avoid receiving live vaccines for measles, mumps, rotavirus, varicella, influenza, and rubella while on treatment with Globucel 5gm Injection 100ml.

Q 4. How do you know if Globucel 5gm Injection 100ml therapy works for you?

It may take up to 4 weeks of regular Globucel 5gm Injection 100ml therapy to notice a steady improvement in your symptoms. Your healthcare provider will suggest a suitable alternative if you do not notice any changes.

Q 5. What are the common side effects of Globucel 5gm Injection 100ml?

The common side effects of Globucel 5gm Injection 100ml are rash, itching, wheezing, difficulty in breathing, swelling of the eyelids, face, lips, throat, or tongue, extremely low blood pressure with symptoms like dizziness, confusion, fainting, and a fast pulse.


Fact Box of Globucel 5gm Injection 100ml

Molecule Name: Human Normal Immunoglobulin 

Therapeutic class:  Immunostimulants

Pharmacological class: Immunoglobulin derivatives

Indications: 

1. Treat inflammatory disorders

2. Primary immunodeficiency diseases (PID)


References

  1. Biotest Pharma GmbH, Electronic medicines compendium (EMC), [ Revised on March 2020] [ Accessed on 30th June 2023], https://www.medicines.org.uk/emc/files/pil.576.pdf
  2. CSL Behring LLC, US Food and Drug Administration, [ Revised on Sept 2017] [ Accessed on 30th June 2023], https://www.fda.gov/files/vaccines%2C%20blood%20%26%20biologics/published/Package-Insert---Privigen.pdf
  3. Octapharma USA Inc., US Food & Drug Administration, [Revised on Mar 2022] [Accessed on 30th June 2023], https://www.fda.gov/media/70911/download
  4. Novaretti MC, Dinardo CL, Immunoglobulin: production, mechanisms of action and formulations, Rev Bras Hematol Hemoter, 2011, 33(5), 377-82, [Accessed on 30th June 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415776/pdf/rbhh-33-377.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.