Globuprime 5gm Injection 100ml is used for:

• Managing primary immunodeficiency disorders (PID)

• Controlling inflammation in certain autoimmune diseases

• Reducing the severity and frequency of infections in people with weak immune systems

Globuprime Injection 100ml works by restoring normal immunoglobulin G (IgG) levels in the blood. It binds to specific immune cell receptors and regulates immune activity. This helps reduce inflammation, balance immune system responses, and lower infection risk in people with immune deficiencies.

Before starting Globuprime 5gm Injection, inform your doctor about all medications you are currently taking, including prescription drugs, over-the-counter medicines, herbal supplements, and vitamins. Immunoglobulin therapy may reduce the effectiveness of certain live vaccines like measles, mumps, and rubella. Your doctor will advise you on necessary precautions and any adjustments needed.

• Store in a refrigerator between 2°C and 8°C.

• Do not freeze.

• Keep out of reach of children.

• Protect from light and excessive heat.

Globuprime 5gm Injection 100ml is given as an intravenous infusion (into a vein) by trained healthcare professionals in a hospital or clinical setting. Your doctor will decide the appropriate dosage and duration based on your age, weight, medical condition, and response to treatment.

Like all medicines, Globuprime 5gm Injection 100ml can cause side effects, although not everyone experiences them.

Serious side effects include:

• Severe allergic reactions (rash, swelling of lips, face, or throat, breathing difficulties)

• Meningitis (inflammation of brain membranes)

• Respiratory failure

• Migraines

• High blood pressure

• Blood clots in the lungs

• Hemolysis (breakdown of red blood cells)
  
  

Common side effects include:

• Rash

• Itching

• Wheezing

• Breathing difficulty

• Swelling of eyelids

• Fever

• Confusion

• Dizziness

• Low blood pressure
  

• Stay hydrated during and after infusion to prevent dehydration-related side effects.

• Avoid receiving live vaccines for at least 3 months after your last dose unless advised by your doctor.

• Inform your doctor if you have any kidney, heart, liver, or lung conditions before starting treatment.

• Monitor for any allergic reactions, especially during the first few hours of infusion.

• If you feel dizzy or tired, avoid driving or handling machinery.

• Always attend your follow-up appointments for necessary blood tests and health monitoring.

1. Biotest Pharma GmbH, Electronic medicines compendium (EMC), [ Revised on March 2020] [ Accessed on 30th June 2023], https://www.medicines.org.uk/emc/files/pil.576.pdf
2. CSL Behring LLC, US Food and Drug Administration, [ Revised on Sept 2017] [ Accessed on 30th June 2023], https://www.fda.gov/files/vaccines%2C%20blood%20%26%20biologics/published/Package-Insert---Privigen.pdf
3. Octapharma USA Inc., US Food & Drug Administration, [Revised on Mar 2022] [Accessed on 30th June 2023], https://www.fda.gov/media/70911/download
4. Novaretti MC, Dinardo CL, Immunoglobulin: production, mechanisms of action and formulations, Rev Bras Hematol Hemoter, 2011, 33(5), 377-82, [Accessed on 30th June 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415776/pdf/rbhh-33-377.pdf