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Hicoly 4.5MIU Injection
Salt Composition : Colistimethate Sodium
Manufacturer : INTAS PHARMACEUTICALS LTD
Origin of Medicine : India
Introduction to Hicoly 4.5miu Injection
Hicoly 4.5MIU Injection contains the active ingredient Colistimethate sodium. It is an antibiotic that belongs to a group of medications called polymyxins. It is used to treat certain types of infections caused by bacteria. This medicine is commonly used when other antibiotics are not suitable. It is sometimes given as an inhalation to treat chronic chest infections in patients with cystic fibrosis.
This medicine is used when these infections are caused by specific bacteria called Pseudomonas aeruginosa. Do not use Hicoly 4.5MIU Injection if you are allergic to colistimethate sodium, colistin, or to other polymers in the medication. Inform your doctor if you have kidney problems or suffer from myasthenia gravis (weakness in skeletal muscles), porphyria (a group of disorders caused by an over-accumulation of porphyrin, which helps hemoglobin, the protein that carries oxygen in the blood), and asthma. Tell your doctor if you are pregnant, breastfeeding, or planning to get pregnant during the treatment.
Serious allergic reactions can happen even with the first dose of Hicoly 4.5MIU Injection in some patients. They can include rapid development of rashes, swelling of the face, tongue, and neck, and inability to breathe. You should seek urgent medical attention if you experience signs of an allergic reaction. Do not stop your treatment early without consulting a doctor. Your doctor will decide how long your treatment should last.
Uses of Hicoly 4.5miu Injection
- To treat certain bacterial infections
Therapeutic Effects of Hicoly 4.5miu Injection
Hicoly 4.5MIU Injection, a polypeptide antibiotic, penetrates and disrupts the bacterial cell membrane of susceptible strains of aerobic gram-negative bacteria. It works by killing bacteria.
Interaction of Hicoly 4.5miu Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Hicoly 4.5MIU Injection and reduce its effectiveness by causing undesirable side effects.
More Information about Hicoly 4.5miu Injection
- Do not store above 25°C.
- Store in the original package to protect from light.
- Keep the injection away from the reach of children and pets.
How to consume Hicoly 4.5miu Injection
A doctor or nurse in a hospital or clinic setting will give it to you. Depending on the reason, the drug may be given by fast or slow injection into a vein. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.
Safety Advices for Hicoly 4.5miu Injection
Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Hicoly 4.5MIU Injection will only be given to a pregnant woman if it is needed.
Breastfeeding is not recommended in patients taking Hicoly 4.5MIU Injection because the medicine passes into the breast milk in small amounts and may harm your baby.
It is unknown whether Hicoly 4.5MIU Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Limited information is available on the use of Hicoly 4.5MIU Injection in patients with liver diseases. Inform your physician if you have any liver diseases or problems before initiating the therapy.
It is unknown whether consuming alcohol is safe during the treatment with Hicoly 4.5MIU Injection. Inform your doctor if you are a chronic drinker.
Hicoly 4.5MIU Injection may make you feel tired, dizzy, or sleepy. It is unsafe to drive or operate heavy machinery after taking this medicine.
Side Effects of Hicoly 4.5miu Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Numbness or tingling
- Dizziness or loss of balance
- Changes in blood pressure
- Slurred speech
- Vision problems
- Confusion and mental problems
- Breathing difficulty
- Respiratory tract paralysis
- Kidney damage
Word of Advice
This medicine may cause kidney damage; your doctor will perform routine kidney function test to monitor the safety of this medicine. This medicine may make you feel dizzy or cause numbness and tingling in your hands and feet. Do not drive or operate heavy machines while taking this medicine. Tell your doctor immediately if you have severe, continuous, or bloody diarrhea. Sometimes injection site reactions, including itching, burning, swelling, or a lump under your skin, may occur.
Q 1. Is Hicoly 4.5MIU Injection available in different forms?
Hicoly 4.5MIU Injection is available in various forms, including intravenous (IV) injection, inhalation, and oral capsules. Your physician will decide the route of administration based on the type and severity of the infection and other factors.
Q 2. Are there any common side effects of Hicoly 4.5MIU Injection?
Common side effects of Hicoly 4.5MIU Injection may include dizziness, numbness or tingling sensation, especially in the face, nausea, vomiting, diarrhea, and kidney function changes. It is important to report any unusual or severe side effects to your healthcare provider.
Q 3. Is there any specific monitoring required during the Hicoly 4.5MIU Injection treatment?
Hicoly 4.5MIU Injection treatment requires careful monitoring of kidney function because this medicine can cause kidney damage. Your healthcare provider may perform regular kidney function tests to ensure the medication is used safely and effectively.
Q 4. Can Hicoly 4.5MIU Injection be used in pediatric patients?
Hicoly 4.5MIU Injection can be used in pediatric patients, but the dosage and administration may vary depending on the child's age, weight, and specific medical condition. It is important to follow the healthcare provider's instructions and closely monitor the child's response to treatment.
Q 5. Can Hicoly 4.5MIU Injection be given for viral infections or the common cold?
Hicoly 4.5MIU Injection is an antibiotic specifically used for treating bacterial infections. It is ineffective against viral infections such as the common cold or flu. Consult your doctor for more advice.
Fact Box of Hicoly 4.5miu Injection
|Molecule name: Colistimethate Sodium||Therapeutic class: Antibiotics|
|Pharmacological class: Polymyxin antibiotic agent||Indications: Treat certain bacterial infections|
- Monarch Pharmaceuticals, US Food and Drug Administration, [ Revised on Oct 2006] [ Accessed on 13th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050108s026lbl.pdf
- Millmount healthcare LTD., Electronic medicines compendium (emc), [ Revised on May 2022] [ Accessed on 13th June 2023], https://www.medicines.org.uk/emc/files/pil.1094.pdf
- Koomanachai P, Tiengrim S, Kiratisin P, Thamlikitkul V. Efficacy and safety of colistin (colistimethate sodium) for therapy of infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii in Siriraj Hospital, Bangkok, Thailand. Int J Infect Dis. 2007 Sep;11(5):402-6. doi: 10.1016/j.ijid.2006.09.011. Epub 2007 Feb 8. PMID: 17291803.
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