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Isogen 100mg Capsule
Last updated on 10 Apr 2026 | 12:21 PM (IST)
₹4476
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Introduction
Isogen 100mg Capsule is a targeted therapy containing the active constituent palbociclib. It belongs to the group of anticancer medications known as cyclin-dependent kinase inhibitors and is widely prescribed in advanced breast cancer care. Patients often compare options such as Isogen 100mg vs 125mg based on their doctor’s recommendation and treatment tolerance. The Isogen 100mg manufacturer ensures quality and consistency in formulation.
It is used in treating hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic (has spread to other parts of the body) breast cancer. It is usually given in combination with other anticancer medicines. Patients and caregivers frequently check details such as Isogen 100mg price, Palbociclib 100mg Isogen cost, and Isogen 100mg availability before starting therapy. Many also explore options to Buy Isogen 100mg online India from reliable sources for better access.
Common side effects associated with Isogen 100mg Capsule include nausea, vomiting, diarrhoea, tiredness, hair loss, dry skin, rash, infections, nose bleed, decreased appetite, low blood cell counts, swelling of lips and mouth, changes in taste, dry eye, blurred vision, and increased tearing. Inform your doctor if any of these side effects persist or worsen. In some cases, doctors may evaluate Isogen 100mg substitutes depending on patient response and tolerance.
Uses
Isogen 100mg uses is
Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How Isogen 100mg Capsule works
Isogen 100mg Capsule works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
Interaction of Isogen 100mg Capsule with other drugs
Inform your doctor about all medications, including prescribed, over-the-counter, nutritional or vitamin supplements and herbal products that you are taking or have taken before the treatment. Concurrent use of Isogen 100mg Capsule with CYP3A4 inhibitors such as fentanyl has reported increased fentanyl toxicity. certain medications may interact with the effectiveness of this drug.
Storage Conditions
Keep Isogen 100mg Capsule out of sight and reach of children.
Store at 20°C to 25°C.
How to take Isogen 100mg Capsule
Take Isogen 100mg Capsule exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.
Safety Advice
Breast Feeding
It is not recommended to take Isogen 100mg Capsule while breastfeeding as it is not known whether it passes into the breast milk.
Alcohol
It is unknown whether it is safe to drink alcohol while taking Isogen 100mg Capsule. Check with your doctor for advice.
Liver
Inform your physician if you have any liver disorders before taking Isogen 100mg Capsule, as it should be used with caution in liver disorder patients.
Lungs
Inform your physician if you have any lung conditions before taking Isogen 100mg Capsule, as it should be used with caution in liver disorder patients.
Driving
Isogen 100mg Capsule can cause tiredness. Avoid driving if you are unwell.
Pregnancy
It is not recommended to take Isogen 100mg Capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Isogen 100mg side effects are
Serious side effects of Isogen 100mg Capsule are:
Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
Lung inflammation (chest pain, dry cough, or difficulty breathing)
Common side effects of Isogen 100mg Capsule are:
Tiredness
Hair loss
Dry skin, rash
Infections
Low blood cell counts
Decreased of appetite
Nausea, vomiting
Diarrhea
Swelling of lips and mouth
Changes in taste
Nose bleed
Dry eye, blurred vision, increased tearing
Expert Tips
Avoid grapefruit, grapefruit juice, and products containing St. John’s wort during treatment
Use effective birth control during treatment
For females: continue for at least 3 weeks after the last dose.
For males: continue for at least 14 weeks after the last dose.
This medication may affect fertility, so discuss any concerns with your doctor.
Regular blood tests may be required to monitor blood cell levels during treatment.
FAQs
Q1.
Is Isogen 100mg Capsule targeted therapy?
Yes, Isogen 100mg Capsule is a targeted therapy. This medication belongs to the class of cyclin-dependent kinase inhibitors.
Q2.
Does Isogen 100mg Capsule affect blood cell count?
Isogen 100mg Capsule might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking Isogen 100mg Capsule are advised.
Q3.
Does Isogen 100mg Capsule affect fertility?
Yes, Isogen 100mg Capsule may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.
Q4.
Can children use Isogen 100mg Capsule?
No, Isogen 100mg Capsule is not recommended for adolescents and children under 18.
Q5.
Do you lose hair on Isogen 100mg Capsule?
Yes, Taking Isogen 100mg Capsule can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.
Fact Box
Molecule name | Palbociclib |
Pharmacological class | Anticancer agents |
Therapeutic class | Cyclin-dependent kinase inhibitor |
Indications | HR-positive, HER2-negative advanced or metastatic breast cancer |
References
- Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
- Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
- Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
- Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
Disclaimer
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Author Details

Written By
Dr. Vijayalakshmi N.
BDS

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 10 Apr 2026 | 12:21 PM (IST)

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