Lupizotib 40mg Tablet contains Cabozantinib, a medicine classified under tyrosine kinase inhibitors. This targeted therapy works by blocking specific enzymes that promote the growth and spread of cancer cells.

Doctors often prescribe Lupizotib 40 mg to treat adults with certain types of cancers. This includes advanced kidney cancer, advanced or metastatic differentiated thyroid cancer, and liver cancer in cases where previous treatments like Sorafenib are no longer effective.

Before starting this medication, it is essential to inform your doctor if you have liver disorders, high blood pressure, heart problems, or any history of bleeding issues. Additionally, notify your healthcare provider if you are pregnant, planning pregnancy, or breastfeeding. The use of effective contraception is recommended during treatment and for at least four months after the last dose.

Doctors prescribe Lupizotib 40mg Tablet for the following conditions:

• Advanced renal cell carcinoma (a type of kidney cancer)

• Liver cancer

• Locally advanced or metastatic differentiated thyroid cancer

If you are wondering about Lupizotib 40 uses, always consult your doctor for condition-specific advice.

Lupizotib Tablet uses its active ingredient to target specific proteins called receptor tyrosine kinases. These proteins play a role in tumor growth, angiogenesis (formation of new blood vessels), and metastasis. By blocking these proteins, Lupizotib 40mg Tablet helps slow down or stop the growth of cancer cells.

Before starting Lupizotib 40mg Tablet, inform your doctor about all medications you currently take, including prescription drugs, over-the-counter products, vitamins, and herbal supplements. Medicines like certain antibiotics, St. John's Wort, and blood pressure drugs can interact with Lupizotib 40mg Tablet, affecting its efficacy or increasing side effects.

• Store at temperatures below 30°C

• Keep away from children and pets

• Avoid exposure to light

• Do not consume grapefruit or grapefruit juice during the treatment, as it may increase medicine levels in your blood

Take Lupizotib 40mg Tablet exactly as prescribed by your doctor. It is usually taken once a day. Swallow the tablet whole with water. Do not crush, chew, or split the tablet.

If you forget a dose and it has been less than 12 hours, take it as soon as possible. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule.

All medications can cause side effects, but not everyone will experience them. Some may be mild and manageable, while others may require medical attention.

Serious Side Effects:

• Gastrointestinal perforation

• Severe bleeding

• Difficulty breathing

• Wound healing issues

• Loss of consciousness

• Blood in urine or stools

• Severe mouth and jaw pain

• Coughing up blood
  
  

Common Side Effects:

• Dehydration

• Difficulty swallowing

• Ringing in the ears

• Blood clots

• Fluctuation in blood sugar levels

• Low albumin levels

• Electrolyte imbalance

• Elevated liver enzymes

• Use effective contraception during treatment and for four months afterward

• Avoid grapefruit or grapefruit juice

• Inform your doctor about any history of thyroid issues

• Report any sudden weight gain, fatigue, or changes in your voice

• Stay hydrated to reduce the risk of dehydration

• Do not stop the medicine without consulting your doctor

• If concerned about Lupizotib 40 mg price, discuss generic or alternative options with your pharmacist

1. Ipsen Pharma, Electronic Medicines Compendium (EMC), [Revised on July 2022] [Accessed on 25th April 2023], Cabometyx 20 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) (medicines.org.uk)
2. Exelixis, Inc., [Revised on Oct 2020] [Accessed on 25th April 2023], https://www.cometriq.com/downloads/Cometriq_Full_Prescribing_Information.pdf
3. Gregory A. Brent and Ronald J. Koenig, Thyroid and Antithyroid Drugs, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 2018, 787-801.