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Megebuzz Tablet
Last updated on 26 Sep 2026 | 08:41 AM (IST)
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Introduction
Megebuzz Tablet contains the active substance Megestrol. It belongs to a category of medicines known as progestogens and is mainly used to treat certain hormone dependent cancers such as breast cancer. It is a synthetic form of the naturally occurring progesterone hormone. Megebuzz Tablet is also commonly prescribed as part of Megebuzz Tablet weight gain treatment to manage unexplained weight loss, cachexia or weakness, and anorexia or loss of appetite in patients with cancer or weakened immune systems.
Progestogens like Megebuzz Tablet are used in patients whose disease has progressed despite conventional anti estrogen therapy. Before starting treatment, your physician will assess the estrogen receptor status to confirm that the breast cancer is estrogen receptor positive. The Megebuzz Tablet price offered is affordable and makes treatment accessible, if Megebuzz Tablet alternatives are suitable based on your treatment needs and you doctro will decide the alternatives.
Uses
Megebuzz Tablet uses in cancer are
Treatment of hormone-dependent cancer (endometrial cancer, breast cancer)
Treatment of anorexia, cachexia or unexplained weight loss
How Megebuzz Tablet Works
Megebuzz Tablet exhibits anticancer properties by interacting with steroidal receptors. It suppresses steroid production by the adrenal glands and androgen secretion by the ovaries in postmenopausal women. It also prevents the breakdown of cytokines and stimulates appetite in chronic disease-induced anorexia and cachexia.
Interaction of Megebuzz Tablet with other drugs
Antidiabetic Medicines such as Insulin or Metformin (Moderate)
Megebuzz Tablet can increase blood sugar levels, which may reduce the effectiveness of diabetes medicines. Regular blood glucose monitoring and dose adjustment may be required.Blood Thinners such as Warfarin (Moderate)
Megebuzz Tablet may alter the effect of anticoagulants, increasing the risk of bleeding or clotting. Close monitoring of clotting parameters is advised.Corticosteroids like Prednisolone or Dexamethasone (Moderate)
Using Megebuzz Tablet with corticosteroids may increase the risk of adrenal suppression, especially with long term use or sudden withdrawal.Immunosuppressive Medicines (Moderate)
When taken together, Megebuzz Tablet may further weaken immune response, increasing the risk of infections.Hormonal Therapies or Estrogen Containing Medicines (Mild to Moderate)
Concurrent use may increase hormonal side effects such as fluid retention or blood clot risk.
Important Note
Always inform your doctor about all medicines you are taking before starting Megebuzz Tablet. Do not start or stop any medicine without medical advice.
Storage Information
Store below 25°C, protected from light and moisture.
Keep out of reach of children.
How to take Megebuzz Tablet
Swallow the tablet whole with water. Your physician will decide the ideal dose for you, depending on your condition.
Safety Advices
Pregnancy
This medicine is unsafe to consume during pregnancy. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.
Breast Feeding
Consult your physician before taking this tablet if you are a breastfeeding mother.
Lungs
Inform your physician if you have any lung diseases before taking Megebuzz Tablet.
Liver
Inform your physician before starting this treatment if you have liver problems. Your physician will monitor your liver functions regularly.
Alcohol
It is not known whether it is safe to consume alcohol with Megebuzz Tablet. Please consult your doctor.
Driving
Avoid driving or using machinery if you experience side effects.
Side Effects
Side effects of Megebuzz Tablet are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
Swelling of the face, lips, tongue
Skin rash
Breathing difficulty
Blood clot in the lungs
Heart problems
Common:
Weight gain and increased appetite
Hot flushes
High BP
High blood sugar levels
Rounded face
Constipation
Swelling of vein
Mood changes
Hair loss
Diarrhea
Tiredness and weakness
Impotence
Passing wind
Frequent urination
Nausea, vomiting
Fluid accumulation
Pain
Expert Tips
Inform your doctor if you have a history of kidney problems, liver issues, or allergies before starting this medication.
Your kidney function, liver function, blood pressure, and blood sugar levels should be regularly monitored during treatment.
Avoid using this medicine during pregnancy or while planning for pregnancy, as it may harm the developing baby.
Do not stop taking this medication without your doctor’s advice, as sudden discontinuation may worsen your condition.
Seek medical help immediately if you notice swelling or pain in the limbs, chest pain, shortness of breath, severe headache, or vision changes.
Frequently Asked Questions(FAQs)
Q1.
Does Megebuzz Tablet cause weight gain?
Yes, it is a common side effect which is caused due to an increase in appetite. It leads to an increase in fat and body mass. If there is excessive weight gain patients are advised to consult the doctor.
Q2.
Is Megebuzz Tablet safe to use during pregnancy?
No, it is unsafe to use this medication in pregnancy because it causes harmful effects in the developing baby. Patients are asked to avoid this medication if they are planning for pregnancy or during pregnancy.
Q3.
Does Megebuzz Tablet stop periods?
No, it doesn't stop periods and it can cause excessive bleeding. consult the doctor if there is any excessive bleeding.
Q4.
What are the side effects of the Megebuzz Tablet?
The common side effects of Megebuzz Tablet are weight gain, increase in appetite, high blood pressure, constipation, rounded face, mood changes, hair loss, tiredness and weakness, nausea, vomiting, swelling of the vein.
Q5.
Best way to take Megebuzz Tablet?
Megebuzz Tablet should be taken as prescribed by the doctor and it can be taken with or without food, preferably at the same time daily. It is important to take this medicine even when the patient is feeling well and don't stop this medication without the proper advice of the doctor as it will worsen the condition.
Q6.
Can I drive after taking the Megebuzz Tablet?
It is unsafe to use this medication while driving as it causes dizziness and patients may lack concentration and alertness.
Fact Box
Molecule name: | Megestrol |
Pharmacological class: | Anti-neoplastics |
Therapeutic class: | Progestins |
Indications: | 1. Treatment of hormone-dependent cancer (endometrial cancer, breast cancer) 2. Treatment of anorexia, cachexia or unexplained weight loss |
References
Bausch and Lomb UK Ltd., Electronic Medicines Compendium (EMC), [Revised on Sep 2020] [Accessed on 17th Jul 2021], https://www.medicines.org.uk/emc/files/pil.11135.pdf
alniche Life Sciences Pvt Ltd., [Revised on 2021] [Accessed on 19th Jul 2021], https://www.alniche.com/product/megahenz/
Bines et al., Activity of megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial, Annals of Oncology, 2014, 25(4), 831-836, https://www.annalsofoncology.org/action/showPdf?pii=S0923-7534%2819%2936501-9
G.G. Dark, A.R. Abdul Razak, Oncology, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 259-282.
Disclaimer
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Author Details
Written By
P. Thirumal Reddy
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 26 Sep 2026 | 08:41 AM (IST)
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