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Mitomycin 40mg Injection
Salt Composition : Mitomycin
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
Introduction to Mitomycin 40mg Injection
Mitomycin 40mg injection is an antimetabolite drug belonging to the class of alkaloids cytotoxic agents, containing the active ingredient Mitomycin. It is used to treat certain types of cancer of the breast, pancreas, lungs, and stomach. This injection is used alone or in combination with other anti-cancer medicines in combination with chemotherapy.
The common side effects that are likely to occur with this medicine are nausea, vomiting, tiredness, bruising, shortness of breath, and numbness. Other serious side effects include swelling of lips, severe lung disease, and kidney problems. Inform your physician if you face any of the symptoms. It is given right away or later with anticancer medicines.
Before taking this injection, please inform your doctor if you have been recently vaccinated or if you have any medical conditions especially kidney, blood or liver diseases or breathing disorders. This drug can lead to blood disorders thus it is necessary to have regular blood tests while undergoing treatment. This medicine should not be used if you are allergic to any of its ingredients. Tell your physician about all the medications you are taking recently, including herbal medicines and supplements, before taking this drug.
Uses of Mitomycin 40mg Injection
Mitomycin 40mg injection is used to treat
- Pancreatic cancer, breast cancer and stomach cancer
- As an adjunct to ab externo glaucoma surgery
Therapeutic Effects of Mitomycin 40mg Injection
It is an alkylating drug, which works by interfering with genetic material (DNA) synthesis and the induction of DNA damage, leading to the death of cancer cells.
Interaction of Mitomycin 40mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Mitomycin 40mg Injection and reduce effectiveness by causing undesirable side effects
More Information about Mitomycin 40mg Injection
- Store Mitomycin 40mg injection in the original package at room temperature (25°C). Do not freeze.
- Keep it out of reach from children and pets.
- It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose
How to consume Mitomycin 40mg Injection
The medicine will be administered to you by a healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. It is intended for topical application to the surgical site of glaucoma filtration surgery. It is not intended for intraocular administration. During the infusion, the patient will be closely monitored for any adverse reactions, such as allergic reactions or changes in blood pressure or heart rate. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors.
Safety Advices for Mitomycin 40mg Injection
It is unknown whether Mitomycin 40mg injection can be administered during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
It is not known if Mitomycin 40mg injection passes into your breast milk or if it will affect your baby or your breast milk. Please consult your doctor before breastfeeding.
It is not known whether Mitomycin 40mg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
It is unknown whether Mitomycin 40mg injection can be administered to patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this drug.
It is unknown whether consuming alcohol interacts with Mitomycin 40mg injection. Please consult your doctor for more advice.
It is unsafe to drive vehicles or operate heavy machinery after taking Mitomycin 40mg injection because this drug contains a small amount of alcohol which may cause dizziness and impair your concentration.
Side Effects of Mitomycin 40mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Severe allergic reactions (faintness, skin rash, swelling of lips, face and airway with difficulty in breathing, loss of consciousness)
- Severe lung disease
- Kidney problems
- Nausea, vomiting
- Low blood cell count
- Cough, shortness of breath
- Bruising, bleeding
- Numbness, swelling and painful redness on palms and soles
Word of Advice
Mitomycin 40mg Injection can cause harm to a developing fetus and should not be given during pregnancy, effective contraception should be followed up. This drug can cause fatigue, so encourage the patient to take enough rest and self-care during treatment. Also, advise the patient to avoid contact with people who are sick, practice good hand hygiene, and take other steps to reduce their risk of infection. In stomach cancer, this injection may be used in combination with other chemotherapy drugs such as fluorouracil (5-FU) and cisplatin. This combination therapy is often used in patients with advanced or metastatic stomach cancer that has spread to other parts of the body. This drug can lower your body's ability to fight infections, so it's important to take steps to avoid exposure to germs and infections. Intake immune booster foods like broccoli, ginger, spinach in your daily life.
Q 1. What is Mitomycin 40mg injection used for?
Mitomycin 40mg Injection is used to treat various types of cancer, including pancreas, breast, and stomach cancers.
Q 2. How is Mitomycin 40mg injection administered?
Mitomycin 40mg Injection can be administered intravenously, intravesically, or topically, depending on the type of cancer being treated.
Q 3. What are the common side effects of Mitomycin 40mg injection?
The most common side effects of Mitomycin 40mg Injection include nausea, vomiting, diarrhea, fatigue, hair loss, mouth sores, and increased risk of infection.
Q 4. Can Mitomycin 40mg injection be given during pregnancy?
No, Mitomycin 40mg Injection can cause harm to a developing fetus and should not be given during pregnancy.
Q 5. What precautions should I take while receiving Mitomycin 40mg injection?
It is important to practice good hand hygiene, avoid contact with people who are sick, and take other steps to reduce your risk of infection while receiving Mitomycin 40mg Injection.
Fact Box of Mitomycin 40mg Injection
Molecule name: Mitomycin
Therapeutic class: Anti-metabolite
Pharmacological class: Alkaloids cytotoxic agents
1.Pancreatic cancer, breast cancer and stomach cancer
2.As an adjunct to ab externo glaucoma surgery
- Accord Healthcare Limited, Electronic Medicines Compendium (emc), [Revised on Feb 2019] [ Accessed on 30th Nov 2021], https://www.medicines.org.uk/emc/files/pil.1956.pdf
- Mobius Therapeutics, US Food and Drug Administration, [Revised on Jan 2012] [ Accessed on 30th Nov 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022572s000lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
- Hadeer Sinawe, Damian Casadesus; Mitomycin; NCBI Bookshelf; Updated on 29/07/2021; Accessed on 01/12/2021; https://www.ncbi.nlm.nih.gov/books/NBK562249/
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