Mitomycin 40mg injection is used to treat

• Pancreatic cancer, breast cancer and stomach cancer
• As an adjunct to ab externo glaucoma surgery

It is an alkylating drug, which works by interfering with genetic material (DNA) synthesis and the induction of DNA damage, leading to the death of cancer cells.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Mitomycin 40mg Injection and reduce effectiveness by causing undesirable side effects

• Store Mitomycin 40mg injection in the original package at room temperature (25°C). Do not freeze.
• Keep it out of reach from children and pets.
• It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose

The medicine will be administered to you by a healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

Severe

• Severe allergic reactions (faintness, skin rash, swelling of lips, face and airway with difficulty in breathing, loss of consciousness)
• Severe lung disease
• Kidney problems

Common

• Nausea, vomiting
• Low blood cell count
• Cough, shortness of breath
• Inflammation
• Bruising, bleeding
• Numbness, swelling and painful redness on palms and soles

Mitomycin 40mg Injection can cause harm to a developing fetus and should not be given during pregnancy, effective contraception should be followed up. This drug can cause fatigue, so encourage the patient to take enough rest and self-care during treatment. Also, advise the patient to avoid contact with people who are sick, practice good hand hygiene, and take other steps to reduce their risk of infection. In stomach cancer, this injection may be used in combination with other chemotherapy drugs such as fluorouracil (5-FU) and cisplatin. This combination therapy is often used in patients with advanced or metastatic stomach cancer that has spread to other parts of the body. This drug can lower your body's ability to fight infections, so it's important to take steps to avoid exposure to germs and infections. Intake immune booster foods like broccoli, ginger, spinach in your daily life.

1. Mobius Therapeutics, US Food and Drug Administration, [Revised on Jan 2012] [ Accessed on 30th Nov 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022572s000lbl.pdf
2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
3. Hadeer Sinawe, Damian Casadesus; Mitomycin; NCBI Bookshelf; Updated on 29/07/2021; Accessed on 01/12/2021; https://www.ncbi.nlm.nih.gov/books/NBK562249/