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Moficept 500mg Tablet
Last updated on 31 Mar 2026 | 09:31 AM (IST)
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Moficept 500mg Tablet
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Introduction
Moficept 500mg Tablet, also known as Moficept 500, contains the active ingredient Mycophenolate mofetil. It is an immunosuppressant that belongs to the inosine monophosphate dehydrogenase (IMPDH) inhibitor class. How Moficept 500mg works is by suppressing the immune system to prevent organ rejection in patients who have undergone organ transplants, including kidney, heart, or liver transplantation. This medicine is often prescribed as part of combination therapy with other immunosuppressive drugs to maintain the transplanted organ’s health.
Moficept 500mg for kidney transplant, Moficept 500mg for heart transplant, and Moficept 500mg for liver transplant are commonly used to prevent the body from rejecting the new organ. Patients or caregivers often check the Moficept 500mg price before starting treatment.
This drug is contraindicated during pregnancy due to the risk of birth defects and miscarriage. Women of reproductive age must use effective contraception while taking Moficept 500mg Tablet. Live vaccines should not be administered during treatment because of reduced vaccine effectiveness and increased risk of infection. Individuals on this medication should avoid donating blood during treatment and for at least six weeks after stopping to ensure the drug is fully cleared from the body.
Uses
Moficept 500mg uses are
- Prevent organ transplant rejections.
How Moficept 500mg Tablet works
Moficept 500mg Tablet works by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides. MMF specifically affects the proliferation of activated T and B lymphocytes. These lymphocytes are key players in the immune response that can lead to the rejection of a transplanted organ
Interaction of Moficept 500mg Tablet with other drugs
Inform your doctor about all your medicines, such as over-the-counter medications, prescription medications, vaccinations, nutritional and vitamin supplements, and herbal products. Certain groups of medications may interact with the effects of Moficept 500mg Tablet and reduce its effectiveness by causing undesirable side effects.
Storage conditions
- Store Moficept 500mg Tablet at room temperature between (15°C to 30°C)
- Keep the medicine away from the reach of children and pets.
How to take Moficept 500mg Tablet
It is an orally available prescription drug. Your physician will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Always take Moficept 500mg Tablet as prescribed by your doctor. Do not open, crush, break, or chew the medicine.
Safety Advice for Moficept 500mg Tablet
Breast Feeding
Moficept 500mg Tablet is not recommended for breastfeeding mothers because small amounts of the drug can pass into the mother's milk and affect the nursing baby.
Alcohol
It is unsafe to consume alcohol when taking Moficept 500mg Tablet because it may cause excessive drowsiness or liver problems.
Liver
It is generally considered safe for individuals with liver disease, including those with liver transplants. The dosage and use of Moficept 500mg Tablet may need to be adjusted based on the severity of liver impairment.
Lungs
Moficept 500mg Tablet should be cautiously administered in patients with lung diseases. Dose adjustments are necessary. Inform your physician if you have lung problems before initiating the therapy.
Driving
Driving vehicles or operating machinery while taking Moficept 500mg Tablet is unsafe because it may cause drowsiness and vision problems.
Pregnancy
Moficept 500mg Tablet is known to have harmful effects on the developing fetus and is generally not prescribed for use during pregnancy unless the benefits outweigh the risks.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Moficept 500mg side effects are
Serious
- Infections, fever, or sore throat
- Unusual bleeding or bruising
- Low blood cell count
- Severe allergic reactions
Common
- Higher risk of developing lymphoma and other cancers
- Nausea, abdominal pain
- Diarrhea
- Constipation
- Loss of appetite
- Shortness of breath
- Weight loss
- Increased heartbeat
- Headache
- Blood pressure problem
- Anaemia
Expert Tips
-
Take Moficept 500mg Tablet exactly as prescribed by your doctor.
-
Inform your doctor about all medications you are taking, including prescription, over-the-counter, and herbal products, as they may interact with this medicine.
-
If you are planning to conceive or suspect pregnancy while taking Moficept 500mg Tablet, consult your doctor immediately.
-
Your doctor may recommend switching to safer alternatives or adjusting your treatment plan during pregnancy.
FAQs about Moficept 500mg Tablet
Q1.
Can I breastfeed while taking Moficept 500mg Tablet?
Breastfeeding is generally not recommended while taking Moficept 500mg Tablet. This drug can pass into the mother's breast milk and may hurt the nursing infant. Consult your doctor about breastfeeding if you are taking this tablet.
Q2.
What will happen if I stop taking Moficept 500mg Tablet suddenly?
Stopping your treatment all of a sudden may cause your condition to become worse. Do not stop taking Moficept 500mg Tablet without consulting your doctor.
Q3.
Can I drink alcohol while taking Moficept 500mg Tablet?
It is highly recommended to limit or avoid alcohol consumption while taking Moficept 500mg Tablet. Alcohol can interact with the medication, increasing the risk of side effects or interfering with its effectiveness.
Q4.
Whether Moficept 500mg Tablet can cause miscarriage?
Yes, Moficept 500mg Tablet can cause miscarriage. If you have childbearing potential, use effective contraception before or during treatment and at least six weeks after discontinuing the medication. Discuss contraceptive options with your doctor properly.
Q5.
Can I get vaccinated during the treatment with Moficept 500mg Tablet?
Live vaccines should be avoided while taking Moficept 500mg Tablet due to the risk of infection. Inform your healthcare provider about your immunization history and consult them regarding the appropriate timing of vaccinations.
Fact Box of Moficept 500mg Tablet
|
Molecule name |
Mycophenolate mofetil |
|
Therapeutic class |
Immunosuppressants |
|
Pharmacological class |
Inosine monophosphate dehydrogenase (IMPDH) inhibitor |
|
Indications |
Prevent organ transplant rejections |
References
- Roche Products Limited, European Medicine Consortium (EMC), [Revised on April 2022],[Accessed on 25/05/2023], https://www.medicines.org.uk/emc/files/pil.1103.pdf
- Genentech USA, Inc., [ Revised on Oct 2021] [ Accessed on 25/05/2023], https://www.gene.com/download/pdf/cellcept_prescribing.pdf
- S.E. Marshall, Immunological Factors in Disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 71-96.
- KD Tripathi, Immunosuppressant Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019,.937-945.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Inflammation, Immunomodulation, and Hematopoiesis, 12th Edition, 2011, 1014.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. B. Deiva
Pharm D

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)

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