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Neumab 440mg Injection

Prescription Required

cold-chain

Salt Composition : Trastuzumab

Manufacturer : LUPIN LTD

Origin of Medicine : India

MRP: 19800
Price : 16830
You Save : 2970 (15%)

1 Vial(s) Of 20ml

Prepaid Only. Non-Returnable

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Introduction to Neumab 440mg Injection

Neumab 440mg Injection consists of Trastuzumab as an active constituent, which is indicated for its use in HER 2 breast cancer. In HER 2 positive patients, the breast cancer cells are mostly composed of HER2 proteins that cause rapid development of cancer tumours by serving as a signal to the cancerous. This medication is also used to treat metastatic gastric cancer with increased levels of HER2 proteins.

Her 2 positive breast cancers are most aggressive in nature. The targeted therapy for her 2 positive breast cancer works by selectively targeting the proteins that are responsible for the growth, development, and spread of cancer. Use effective birth control during the treatment and for at least 7 months after the final dose.

Neumab 440mg Injection is not recommended for patients aged under 18, patients who have severe breathing problems or need oxygen treatment. It is necessary to let your physician know if you have any heart problems, breathlessness, or have ever had any other cancer treatment. Make sure you inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start treatment with this medication.


Uses of Neumab 440mg Injection

Neumab 440mg Injection is indicated for its use in the following conditions:

  • Advanced and metastatic breast cancer
  • Metastatic gastric cancer

Therapeutic Effects of Neumab 440mg Injection

The protein called HER2 (human epidermal growth factor receptor 2) is found in abundant amounts on the surface of certain cancer cells, where it stimulates cancer growth. Neumab 440mg Injection selectively binds to HER2 and stops the growth of cancer cells.


Interaction of Neumab 440mg Injection with other drugs

Inform your doctor about any medications you are taking or have taken before the treatment.


More Information about Neumab 440mg Injection

  • Keep Neumab 440mg Injection out of sight and reach of children.
  • Store between 2˚C and 8˚C.

How to consume Neumab 440mg Injection

  • Neumab 440mg Injection shall either be administered before or after surgery.
  • It will be given as an Intravenous infusion for 90 minutes, if well tolerated it shall be administered within 30 minutes for the next doses.

Safety Advices for Neumab 440mg Injection

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Pregnancy

  

Discuss with your physician before taking this Neumab 440mg Injection if you are pregnant or think you might be pregnant. Do not take this medicine during the pregnancy unless advised by the doctor to take it, as it may cause to the unborn baby.

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Breast Feeding

  

Avoid breastfeeding your baby while on the treatment with Neumab 440mg Injection at least for at least seven months after the final dose.

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Lungs

  

Consult your doctor before starting treatment with Neumab 440mg Injection if you have any lung problems.

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Liver

  

You need to tell your physician if you have any liver disorders before starting Neumab 440mg Injection, as it requires dosage adjustment for severe liver impairment.

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Alcohol

  

Consult your doctor if it is safe to consume alcohol while you are on treatment with Neumab 440mg Injection.

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Driving

  

Neumab 440mg Injection can cause unusual tiredness and dizziness. Hence, it is advised to avoid driving or handling machinery during the treatment.


Side Effects of Neumab 440mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.


 

The side effects of Neumab 440mg Injection are listed below:

Common:

  • Heart Problems (Serious)
  • Allergic reactions (Serious)
  • Kidney problems (Serious)
  • Breathing difficulties (Serious)
  • Fever
  • Visual disturbances
  • Nose bleeds or runny nose
  • Hair loss
  • Dizziness
  • Nail disorders
  • Weight loss
  • Loss of appetite
  • Bruising
  • Dry mouth
  • Liver  inflammation
  • Muscle pain
  • Asthma/ lung disorders

Word of Advice

It is suggested to inform your doctor if you have a history of allergic reactions to trastuzumab to avoid life-threatening complications. If you have a history of lung disorder or breathing problems inform your doctor beforehand before the treatment commencement. Avoid planning for pregnancy and breastfeeding for a minimum of 7 months after the last dose. Monitor your heart parameters regularly during the treatment with Neumab 440mg Injection as it may impact the functioning of the heart.


FAQs

Q 1. Is Neumab 440mg Injection injection used as a monotherapy in treating breast cancer?

Neumab 440mg Injection is generally given along with the chemotherapy medication such as paclitaxel or docetaxel or platinum compounds. Sometimes, it is also given with hormonal agents for those patients with elevated hormonal status.

Q 2. Can a Neumab 440mg Injection be consumed during pregnancy?

No, it is unsafe to consume Neumab 440mg Injection while you are pregnant, or this medicine can cause harm to the baby by reducing the amount of amniotic fluid, the fluid surrounding the womb. It can also cause organ developmental issues, such as poor lung development, when consumed during pregnancy. If you are planning for pregnancy, it is advised to discuss birth control methods as this medicine may impair your fertility.

Q 3. Can I breastfeed while on treatment with Neumab 440mg Injection?

No, since it tends to pass into breast milk, it is unsafe to breastfeed. Hence, It is advised not to breastfeed for a minimum of 7 months after the treatment with Neumab 440mg Injection.

Q 4. Does Neumab 440mg Injection cause heart problems?

Yes, Neumab 440mg Injection can damage the heart muscles. Hence to prevent the worsening of symptoms, it is advised to do heart check up every 3 months and continue till 2-5 years after the treatment completion.


Fact Box of Neumab 440mg Injection

Molecule name

trastuzumab

Therapeutic class

Anti-cancer

Pharmacological class

HER2 inhibitors

Indications

Breast Cancer

Manufacturer

Genentech


References

  1. Roche, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 12th July 2022],  https://www.medicines.org.uk/emc/files/pil.3856.pdf
  2. Genentech Inc, [Revised on Feb 2021] [Accessed on 12th July 2022], https://www.gene.com/download/pdf/herceptin_prescribing.pdf
  3. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.

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