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Nitrobest 100mg Tablet
Last updated on 31 Mar 2026 | 09:31 AM (IST)
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Introduction to Nitrobest 100mg Tablet
Nitrobest 100mg tablet contains the active ingredient nitrofurantoin. It is an antibiotic used to prevent and treat infections of the bladder, kidney, and other parts of the urinary tract. It works by killing the bacterial organism that cause infection. Do not take this medicine if you are allergic to nitrofurantoin, other medicines containing nitrofurantoin, or other ingredients. Inform your physician if you are pregnant or breastfeeding or have kidney disease, blood disorders, or G6PD (glucose-6-phosphate dehydrogenase) deficiency.
Inform your physician if you have diabetes, lung disease, liver problems, nervous disorder, or any other illness that cause severe weakness or tiredness, anemia, lack of vitamin B, or any other abnormal blood values. Nitrobest 100mg tablet is not recommended for children below 3 months of age. Report to your doctor if your urine is dark yellow or brown in color, fatigue, yellowing of the skin or eyes, itching, skin rashes, joint pain, abdominal discomfort, nausea, vomiting, loss of appetite, or pale or grey colored stools after taking this medicine because these may indicate liver problems.
Uses of Nitrobest 100mg Tablet
- Prevent and treat infections of the bladder, kidney, and other parts of the urinary tract.
Therapeutic Effects of Nitrobest 100mg Tablet
Nitrobest 100mg tablet exerts its antimicrobial action by inactivating or altering bacterial ribosomal proteins and other macromolecules. As a result of this inactivation, the important biochemical process of protein synthesis, energy metabolism, DNA, RNA synthesis, and cell wall synthesis are inhibited in the bacteria.
Interaction of Nitrobest 100mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Nitrobest 100mg tablet and reduce its effectiveness by causing undesirable side effects.
More Information about Nitrobest 100mg Tablet
- Do not store above 25˚C
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you forgot to take the tablet, take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
How to consume Nitrobest 100mg Tablet
Your doctor will decide the dose and duration of Nitrobest 100mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with food. This will help avoid stomach upset and make the medicine work more effectively. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.
Safety Advice for Nitrobest 100mg Tablet
Breast Feeding
Breastfeeding is not recommended in patients taking Nitrobest 100mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Alcohol
It is unsafe to consume alcohol with Nitrobest 100mg tablet because this may cause symptoms like flushing, increased heartbeat, nausea and vomiting.
Liver
Nitrobest 100mg tablet must be cautiously used in patients with liver problems. Dose adjustments may be necessary. Inform your physician if you have liver disease before starting the treatment.
Lungs
Nitrobest 100mg tablet must be cautiously used in patients with lung problems because this medicine may cause drug-induced pulmonary disease. Inform your physician if you have lung diseases before starting the treatment.
Driving
Nitrobest 100mg tablet may cause dizziness and drowsiness. Driving or operating heavy machinery is unsafe if you experience any symptoms that affect your ability to concentrate and react.
Pregnancy
Do not take Nitrobest 100mg tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment.
Side Effects of Nitrobest 100mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Loss of appetite
- Nausea
- Vomiting
Serious
- Anemia
- Diarrhea
- Hypersensitivity reaction
- Lung infections
- Nerve damage
Word of Advice
Do not take this medicine if you are unable to urinate. It should be cautiously given to the patient with kidney problems. Dose adjustments are needed in patients with kidney failure or severe kidney disease. Complete the whole course of therapy even if you feel better after the first few doses. This medicine may cause diarrhea; inform your physician if it persists longer or is bloody. Your doctor may do lab tests to check the therapy's effectiveness or monitor the unwanted side effects.
FAQs about Nitrobest 100mg Tablet
Q1.
What is the warning of Nitrobest 100mg tablet?
Stop using this medicine and report to your doctor immediately if you face any symptoms of stomach pain, grey-colored stools, dark-colored urine, decreased or loss of appetite, fever, headache, itching, nausea, vomiting, skin rash, or swelling of the feet or lower legs.
Q2.
Is Nitrobest 100mg tablet toxic to kidneys?
Nitrobest 100mg tablet is well known to cause renal impairment and kidney damage. Inform your physician if you have any kidney problems before initiating the therapy.
Q3.
Can Nitrobest 100mg tablet cause jaundice?
The drug may cause acute liver injury when used long-term. The liver impairment is characterized by fever, jaundice, abdominal pain, and nausea.
Q4.
Is Nitrobest 100mg tablet safe in pregnancy?
Nitrobest 100mg tablet is unsafe during the last trimester of pregnancy. Inform your physician if you are pregnant while taking the medicine. Consult your doctor for more advice on pregnancy and breastfeeding.
Q5.
Can I take Nitrobest 100mg tablet without food?
Take Nitrobest 100mg tablet as advised by your doctor. Generally, it should be taken with food to reduce stomach problems and increase its absorption.
Q6.
Can Nitrobest 100mg tablet make me sleepy?
Nitrobest 100mg tablet can make you feel dizzy, drowsy, or sleepy. Inform your physician if you feel dizzy for a longer period.
Fact Box of Nitrobest 100mg Tablet
Molecule name: Nitrofurantoin | Therapeutic class: Antibiotic |
Pharmacological class: Nitrofurons | Indications: Urinary tract infection |
References
- Nitrofurantoin 100 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). Medicines.org.uk. [revised on 2019] [cited 2023 Apr 10]. Available from: https://www.medicines.org.uk/emc/product/3602/smpc
- Macrobid ® (Nitrofurantoin Capsules, USP). [revised on 2021] [cited 2023 Apr 10]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/020064Orig1s029lbl.pdf
- J. Goddard, A.N. Turner, Kidney and Urinary Tract Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 461-523.
- Camille E. Beauduy, Lisa G. Winston, Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 895-903.
Disclaimer
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Author Details
Written By
Dr. Karpagam A.
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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