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Palbotor 100mg Capsule
Last updated on 16 Sep 2026 | 06:18 AM (IST)
₹5425
MRP: ₹8345
(You Save ₹2920)
21 CAPSULE(s) IN A BOTTLE
Sourced from:Manufacturer Authorized Distributor
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₹5425
MRP: ₹8,345.00
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Introduction
Palbotor 100 mg is a targeted therapy containing the active constituent palbociclib. It belongs to the group of anticancer medications known as cyclin-dependent kinase inhibitors. It is used in treating hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic (has spread to other parts of the body) breast cancer. Cancer is a condition in which cells multiply in an uncontrolled and abnormal manner. It is given in combination with certain other anticancer medications.
The common side effects that are likely to associate with Palbotor 100 mg are nausea, vomiting, diarrhea, tiredness, hair loss, dry skin, rash, infections, nose bleed, decreased appetite, low blood cell counts, swelling of lips and mouth, changes in taste, dry eye, blurred vision, and increased tearing. Inform your doctor if any of these side effects disturb or persist in you.
Inform your healthcare provider if you are allergic to Palbotor 100mg and its ingredients. Before taking this Palbotor capsule, it is vital to inform your doctor if you have any signs of infections (fever, chills, or sore throat), liver disorders, kidney disorders, or intolerance to some sugars. Consult your physician immediately if you experience symptoms such as dry cough, chest pain, or difficulty breathing, as it could indicate lung inflammation. Make sure you inform your physician of all the medicines, including supplements and herbal medicines; you are taking before you start treatment with this medication. Use effective birth control during the treatment and at least three weeks after the Palbotor dose. It is not recommended for adolescents and children under 18 years of age. Palbotor price varies by retailer and location.
Uses
Palbotor 100mg Capsule uses:
- Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How Palbotor 100mg Capsule Works
Palbotor 100 mg works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
Interaction of Palbotor 100mg Capsule with other drugs
Inform your doctor about all medications, including prescribed, over-the-counter, nutritional or vitamin supplements and herbal products that you are taking or have taken before the treatment. Concurrent use of Palbotor 100 mg with CYP3A4 inhibitors such as fentanyl has reported increased fentanyl toxicity. certain medications may interact with the effectiveness of this drug.
Storage Conditions
- Keep Palbotor 100 mg out of sight and reach of children.
- Store at 20°C to 25°C.
How to take Palbotor 100mg Capsule
Take Palbotor 100 mg exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.
Safety Advice for Palbotor 100mg Capsule
Breast Feeding
It is not recommended to take Palbotor 100 mg while breastfeeding as it is not known whether it passes into the breast milk.
Alcohol
It is unknown whether it is safe to drink alcohol while taking Palbotor 100 mg capsule. Check with your doctor for advice.
Liver
Inform your physician if you have any liver disorders before taking Palbotor 100 mg, as it should be used with caution in liver disorder patients.
Lungs
It is not unknown whether Palbotor 100 mg can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Palbotor 100 mg can cause tiredness. Avoid driving if you are unwell.
Pregnancy
It is not recommended to take Palbotor 100 mg during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
- Lung inflammation (chest pain, dry cough, or difficulty breathing)
Common
- Tiredness
- Hair loss
- Dry skin, rash
- Infections
- Low blood cell counts
- Decreased of appetite
- Nausea, vomiting
- Diarrhea
- Swelling of lips and mouth
- Changes in taste
- Nose bleed
- Dry eye, blurred vision, increased tearing
Expert tips
-
Avoid grapefruit, its juices, and products containing St. John’s wort during Palbotor 100 mg treatment.
-
Use effective birth control during treatment and for at least three weeks after the final dose for females, and fourteen weeks for males.
-
This medicine may reduce fertility, so consult your physician if you have concerns.
-
Regular blood tests may be required to monitor the effect of Palbotor 100 mg on your blood cells.
FAQs about Palbotor 100mg Capsule
Q1.
Is Palbotor 100 mg targeted therapy?
Yes, Palbotor 100 mg is a targeted therapy. This medication belongs to the class of cyclin-dependent kinase inhibitors.
Q2.
Do you lose hair on Palbotor 100 mg?
Yes, Taking Palbotor 100 mg can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.
Q3.
Can children use Palbotor 100 mg?
No, Palbotor 100 mg is not recommended for adolescents and children under 18.
Q4.
Does Palbotor 100 mg affect fertility?
Yes, Palbotor 100 mg may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.
Q5.
Does Palbotor 100 mg affect blood cell count?
Palbotor 100 mg might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking Palbotor 100 mg are advised.
Fact Box
|
Molecule name: | Palbociclib |
|
Therapeutic class: | Cyclin-dependent kinase inhibitor |
|
Pharmacological class: | Anti-Neoplastics |
|
Indications: | HR-positive, HER2-negative advanced or metastatic breast cancer |
References
- Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
- Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
- Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
- Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
Disclaimer
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Author Details

Written By
Guruvigneshwari M.
M. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 16 Sep 2026 | 06:18 AM (IST)

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