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Postoperative nausea and vomiting.
Chemotherapy-induced nausea and vomiting.

"}},{"id":"2c32f5bf-1f2d-4e53-85d4-380595e220ac","type":"PARA","position":3,"content_placement":1,"data":{"heading":"Therapeutic Effects of Palnox 0.25mg Injection","text":"

It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting. The chemotherapeutic trigger zone(CTZ) contains the receptor serotonin, when this CTZ is stimulated, vomiting occurs. It prevents the signals from serotonin and helps to reduce the symptoms of nausea and vomiting.

"}},{"id":"3cfb431a-c0b5-44fe-b9e3-88bdca56076f","type":"PARA","position":4,"content_placement":1,"data":{"heading":"Interaction of Palnox 0.25mg Injection with other drugs","text":"

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Palnox 0.25mg injection and reduce effectiveness by causing undesirable side effects.

"}},{"id":"a2e5a424-4e64-4ff0-af24-4e81b6b57702","type":"PARA","position":5,"content_placement":1,"data":{"heading":"More Information about Palnox 0.25mg Injection","text":"

Store Palnox 0.25mg injection in the original package at room temperature (25°C). Do not freeze.
Keep it out of reach from children and pets.
It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.

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The medicine will be administered to you by a healthcare professional in a hospital setting. Palnox 0.25mg injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery.

"}},{"id":"006afd74-9892-472d-8124-c5977285e90a","type":"SAFETY_ADVICE","position":7,"content_placement":2,"data":{"heading":"Safety Advice for Palnox 0.25mg Injection","safety_list":[{"id":"5168ca7d-72c7-439b-b7ff-1f4a44bf22c1","advice":"Breast Feeding","tag":"Consult your doctor","description":"

It is not known if Palnox 0.25mg injection passes into your breast milk or if it will affect your baby or your breast milk. Please consult your doctor before breastfeeding.

","imageUrl":"https://assets.mrmed.in/others/file-1674132409667-45039420-Breatfeeding.jpg"},{"id":"6828b726-d7dc-4767-af32-68733a967f29","advice":"Alcohol","tag":"Consult your doctor","description":"

It is unknown whether consuming alcohol interacts with Palnox 0.25mg injection. Please consult your doctor for more advice.

","imageUrl":"https://assets.mrmed.in/others/file-1674132415913-10337479-Alcohol.jpg"},{"id":"b816f49e-8791-435e-8947-bc084e5801d5","advice":"Liver","tag":"Consult your doctor","description":"

It is unknown whether Palnox 0.25mg injection can be administered to patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this drug.

","imageUrl":"https://assets.mrmed.in/others/file-1674132424807-417765861-Liver.jpg"},{"id":"9f350901-f521-4abd-9b8c-551b7161d035","advice":"Lungs","tag":"Consult your doctor","description":"

It is not known whether Palnox 0.25mg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

","imageUrl":"https://assets.mrmed.in/others/file-1674132427859-226731771-Lungs.jpg"},{"id":"8df342eb-6f0c-4332-93dd-a1b8b4a7d35e","advice":"Driving","tag":"unsafe","description":"

It is unsafe to drive vehicles or operate heavy machinery after taking Palnox 0.25mg injection because it contains a small amount of alcohol which may cause dizziness and impair your concentration.

","imageUrl":"https://assets.mrmed.in/others/file-1674132431331-421990512-Driving.jpg"},{"id":"20d085b6-81e7-4232-9535-96252c41879d","advice":"Pregnancy","tag":"Consult your doctor","description":"

It is unknown whether Palnox 0.25mg injection can be administered during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

","imageUrl":"https://assets.mrmed.in/others/file-1674132401469-949914510-Pregnancy.jpg"}]}},{"id":"32d919e1-605f-499f-b4ce-cf130b793dd8","type":"PARA","position":8,"content_placement":1,"data":{"heading":"Side Effects of Palnox 0.25mg Injection","text":"

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

Hives
Swollen face
Breathing trouble
Chest pain

Common

Headache
Fatigue
Dizziness
Abdominal pain

"}},{"id":"ec083a7c-8c4d-43e0-af7c-5ae76b89fd12","type":"PARA","position":9,"content_placement":1,"data":{"heading":"Word of Advice","text":"

Talk to your physician if you have a history of repeated constipation, blockage in the bowel, heart problems, or imbalance of certain minerals (such as potassium and magnesium) in your blood before taking Palnox 0.25mg injection. Inform your doctor or nurse if you are taking any medicines that affect your heartbeat because they could cause a heartbeat problem when taken with this injection.

"}},{"id":"38f727fb-091e-4b56-9bb8-97d9c779bdc9","type":"FAQ","position":10,"content_placement":2,"data":{"heading":"FAQs about Palnox 0.25mg Injection","faq_list":[{"id":"8599a7a1-e927-48e3-ab81-96cdf57fa539","question":"

What are the possible side effects of Palnox 0.25mg injection?

","answer":"

It can cause serious allergic reactions like hives, swollen face, breathing trouble, and chest pain. Some common side effects include headache and constipation.

"},{"id":"ebe6c769-e1fa-4a20-8ef2-28411a2b7a19","question":"

When should you take the Palnox 0.25mg injection?

","answer":"

The first dose of this drug is typically taken before the start of your surgery, chemotherapy, or radiation treatment.

"},{"id":"27ab9146-54f5-425a-87e9-718b209015c9","question":"

How does an Palnox 0.25mg injection work?

","answer":"

Palnox 0.25mg injection works by blocking the action of a chemical called serotonin, which is involved in causing nausea and vomiting.

"},{"id":"efb1b04d-ed7b-440c-95a0-183999f6fe28","question":"

Who should not take an Palnox 0.25mg injection?

","answer":"

Palnox 0.25mg injection should not be taken by individuals who are allergic to it or its ingredients.

"},{"id":"4d723379-31b6-40b3-a4cb-6096b9ece9c0","question":"

What forms does the Palnox 0.25mg injection come in?

","answer":"

Palnox 0.25mg injection is available in the injection form.

"}]}},{"id":"250da768-6944-47e7-94f6-39f43830df38","type":"PARA","position":11,"content_placement":3,"data":{"heading":"Fact Box of Palnox 0.25mg Injection","text":"

Molecule name: Palonosetron

Therapeutic class: Antiemetics

Pharmacological class: 5-HT3 receptor antagonists

Indications:

1.Postoperative nausea and vomiting.

2.Chemotherapy induced nausea and vomiting.

"}},{"id":"8368b5c5-8d16-4cbb-87b2-91681e908a54","type":"PARA","position":12,"content_placement":3,"data":{"heading":"References","text":"

Helsinn Birex Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [Revised on Dec 2021] [ Accessed on 01st March 2023], https://www.medicines.org.uk/emc/files/pil.513.pdf
Fresenius Kabi, US Food and Drug Administration, [Revised on Dec 2018] [Accessed on 01st March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208109s001lbl.pdf
Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1341.
KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, prokinetic and digestant drugs, 7th edition, 2013, 669.

"}},{"id":"49820e4d-a54f-497c-aaae-ffb2957afd06","type":"DISCLAIMER","position":13,"content_placement":5,"data":{"heading":"Disclaimer","text":"

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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