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Pentaglobin 5gm Injection 100ml

Prescription Required

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Salt Composition : Human Normal Immunoglobulin

Manufacturer : PAVIOUR PHARMACEUTICALS PVT LTD

Origin of Medicine : India

MRP: 40399
Price :34470
You Save :5929 (15%)

1 Vial(s) Of 100ml

Prepaid Only. Non-Returnable


Introduction to Pentaglobin 5gm Injection 100ml

Pentaglobin 5gm Injection 100ml is an immunostimulant drug in the category of immunoglobulin derivatives, containing the active ingredient Human Normal Immunoglobulin. It is used as a replacement therapy for individuals with primary immunodeficiency disorders (PIDs), where the body's immune system cannot produce sufficient antibodies to fight off infections. The medication is also used to modulate or regulate the immune system in certain autoimmune and inflammatory conditions. It can help reduce excessive inflammation and suppress abnormal immune responses.

This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Stop taking this tablet and contact your doctor immediately if you develop a rash or skin symptoms. If you have a selective IgA deficiency, there is a risk of developing antibodies against IgA. In such cases, normal human immunoglobulin should be used cautiously or avoided altogether. Inform your physician if you have a history of IgA deficiency. After receiving Pentaglobin 5gm Injection 100ml, it is possible to experience a temporary decrease in the concentration of white blood cells, a condition named as neutropenia (low neutrophil count) which resolves spontaneously within a week.

The administration of normal human immunoglobulin may interfere with the effectiveness of live attenuated vaccines. It is advisable to avoid live vaccines for a certain period after receiving this drug. The overdose of Pentaglobin 5gm Injection 100ml may lead to fluid overload, particularly in patients with pre-existing heart failure or compromised renal function. Patients with such conditions should be carefully monitored during infusion. Inform your doctor of any heart, thyroid, kidney, or liver disease. Your physician may prescribe you a low dose and perform regular blood tests. The use of this medicine during pregnancy or breastfeeding should be discussed with your physician. 


Uses of Pentaglobin 5gm Injection 100ml

  • Primary immunodeficiency disease (PID)
  • Chronic inflammatory demyelinating polyneuropathy (CIDP)
  • Multifocal motor neuropathy

Therapeutic Effects of Pentaglobin 5gm Injection 100ml

Pentaglobin 5gm Injection 100ml works by restoring the immunoglobulin G (IgG) antibodies. It directly binds to the Fc fragment-specific receptors and acts against inflammatory mediators. It induces cell death in B and T cells, eventually reducing inflammation and the severity of infections. It functions by replenishing the antibodies that are lacking in order to combat infections and inflammation. 


Interaction of Pentaglobin 5gm Injection 100ml with other drugs

Inform your physician about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Pentaglobin 5gm Injection 100ml and cause undesirable side effects.The use of human immunoglobulins reduces the effectiveness of some vaccines like mumps, measles,rubella and chickenpox.


More Information about Pentaglobin 5gm Injection 100ml

  • Store Pentaglobin 5gm Injection 100ml in a refrigerator (2°C- 8°C).
  • Do not freeze.

How to consume Pentaglobin 5gm Injection 100ml

Pentaglobin 5gm Injection 100ml is usually administered through a vein (intravenously) by your physician in a hospital setting. It will be infused into your body gradually at first. After then, your doctor might progressively raise the infusion rate.Your physician will decide the correct dosage and duration based on age, body weight, blood viscosity and other disease conditions. 


Safety Advices for Pentaglobin 5gm Injection 100ml

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Pregnancy

  

Pentaglobin 5gm Injection 100mls will be given by your physician during pregnancy only if the benefits outweigh the risks. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment. 

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Breast Feeding

  

Pentaglobin 5gm Injection 100mls should be taken if it is necessary during breastfeeding. Consult your doctor for more advice.

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Lungs

  

It is unknown whether Pentaglobin 5gm Injection 100ml is safe for patients with lung problems. Contact your doctor if you experience any lung-related symptoms.

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Liver

  

Inform your doctor if you have liver disease because Pentaglobin 5gm Injection 100ml should be used cautiously with a liver condition.

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Alcohol

  

It is unknown whether consuming alcohol while taking a Pentaglobin 5gm Injection 100ml is safe. Please speak with your physician.

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Driving

  

Driving vehicles or operating machinery while taking Pentaglobin 5gm Injection 100ml is unsafe because it may cause a lack of coordination and concentration. 


Side Effects of Pentaglobin 5gm Injection 100ml

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.

Serious

  • Severe allergic reaction (rash, itching, swelling of lips, tongue, wheezing, difficulty breathing, low blood pressure with confusion, dizziness, fainting)
  • Meningitis (inflammation of the brain)
  • Respiratory failure
  • Migraine
  • High blood pressure
  • Blood clot in lungs
  • Rupturing of red blood cells

Common

  • Rash
  • Itching
  • Wheezing
  • Difficulty in breathing
  • Swelling of the eyelids
  • Fever
  • Confusion
  • Dizziness
  • Low BP

Word of Advice

If you have a current or past history of a kidney disorder, it is important to inform your physician. They will exercise caution and closely monitor your kidney function during treatment with Pentaglobin 5gm Injection 100ml. Eat a well-balanced diet. You should avoid driving or handling machines if you feel dizzy or tired. The rate of infusion may be connected to some side effects, such as headache, flushing, chills, myalgia, wheezing, tachycardia, lower back pain, nausea, and hypotension. Adherence to the prescribed infusion rate is crucial. Pentaglobin 5gm Injection 100ml may alter some laboratory tests hence it is essential to inform your doctor before screening for any tests. Regular monitoring of urine output and renal function must be followed. 


FAQs

Q 1. How long does it take for Pentaglobin 5gm Injection 100ml to work?

It usually takes 30 to 60 minutes of administration for Pentaglobin 5gm Injection 100ml to start working.

Q 2. How is Pentaglobin 5gm Injection 100ml administered?

Pentaglobin 5gm Injection 100ml is available as a solution for injection, intended for intravenous administration. Your healthcare provider will calculate the accurate dose and duration of this treatment based on your condition and administer this medication as an intravenous infusion.

Q 3. What should you not take with Pentaglobin 5gm Injection 100ml?

Avoid receiving live vaccines for measles, mumps, rotavirus, varicella, influenza, and rubella while on treatment with Pentaglobin 5gm Injection 100ml.

Q 4. How do you know if Pentaglobin 5gm Injection 100ml therapy works for you?

It may take up to 4 weeks of regular Pentaglobin 5gm Injection 100ml therapy to notice a steady improvement in your symptoms. Your healthcare provider will suggest a suitable alternative if you do not notice any changes.

Q 5. What are the common side effects of Pentaglobin 5gm Injection 100ml?

The common side effects of Pentaglobin 5gm Injection 100ml are rash, itching, wheezing, difficulty in breathing, swelling of the eyelids, face, lips, throat, or tongue, extremely low blood pressure with symptoms like dizziness, confusion, fainting, and a fast pulse.

Q 6. Who is not eligible for Pentaglobin 5gm Injection 100ml treatment?

Those who have experienced severe allergic responses to immunoglobulin products or any of the components in the past may not be good candidates for this treatment. Additionally, people with specific medical disorders including congestive heart failure, thrombosis, or renal impairment should utilize it with caution. Before taking Pentaglobin 5gm Injection 100ml, expectant moms and nursing mothers should speak with their healthcare professionals.


Fact Box of Pentaglobin 5gm Injection 100ml

Molecule Name: Human normal immunoglobulin

Therapeutic class:  Immunostimulants

Pharmacological class: Immunoglobulin derivatives

Indications: 

  1. Primary immunodeficiency disease (PID)
  2. Chronic inflammatory demyelinating polyneuropathy (CIDP)
  3. Multifocal motor neuropathy

Dosage form: Intravenous injections

Habit forming: No


References

  1. Biotest Pharma GmbH, Electronic medicines compendium (EMC), [ Revised on March 2020] [ Accessed on 12/02/2024], https://www.medicines.org.uk/emc/files/pil.576.pdf
  2. Takeda pharmaceuticals USA Inc., US Food & Drug Administration, [Revised on Jan 2024], [Accessed on 12th Feb 2024], https://www.fda.gov/media/70812/download
  3. Octapharma USA Inc., US Food & Drug Administration, [Revised on Mar 2022] [Accessed on 12/02/2024], https://www.fda.gov/media/70911/download
  4. Novaretti MC, Dinardo CL, Immunoglobulin: production, mechanisms of action and formulations, Rev Bras Hematol Hemoter, 2011, 33(5), 377-82, [Accessed on 12th Feb 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415776/pdf/rbhh-33-377.pdf 

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