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Prolemax 11.25mg Injection

Prescription Required
Cold Chain Required
leuprolide acetate

4284

MRP: 9312.1

(You Save ₹5028.1)

1 VIAL(s)

54% OFF
Prolemax 11.25mg Injection
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4284

MRP: 9,312.10

Inclusive of all taxes

54% Off

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1 Vial(s)

1 Vial(s)

4284.0/Unit
Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
Info

Salt Composition

LEUPROLIDE ACETATE

Marketer

GLS PHARMA LTD

Prepaid Only. Non-Returnable.

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Introduction

Prolemax 11.25mg Injection consists of the active ingredient Leuprolide acetate. It belongs to the class of medicines called Gonadotropin-Releasing Hormone (GnRH) agonists. Prolemax 11.25mg Injection is prescribed for prostate cancer in men, hormone-responsive breast cancer, endometriosis (where tissue that normally lines the uterus grows outside of it), and uterine fibroids (noncancerous growths of the uterus) in women. This medicine is also used in treating premature puberty (central precocious puberty), a condition where a child’s body begins to develop adult features earlier than expected due to abnormal hormonal release.

Do not receive this injection if you are allergic to Leuprolide acetate or any other related ingredients, such as Goserelin and Triptorlin. Before receiving this medicine, inform your physician if you have liver or kidney impairment, or if you have undiagnosed abnormal uterine bleeding. This treatment should not be taken if you are pregnant or planning pregnancy. During therapy, existing symptoms may temporarily worsen because of increased sex steroid levels in the body. Speak to your physician about any concerns, and report immediately if your child has a progressive brain tumor.

Before starting the treatment, notify your doctor if you have any underlying medical conditions, including diabetes, seizures, heart problems (chest pain or irregular heartbeat), depression, or osteoporosis (bone thinning risk). This medicine is not recommended in pregnant and breastfeeding women or in patients with abnormal vaginal bleeding. Women of childbearing age should use non-hormonal contraceptives during treatment with Prolemax 11.25mg Injection. Male patients should inform their doctor if they have urinary obstruction, have undergone testicle removal surgery, or experience spinal cord pressure, urinary problems, or haematuria (blood in urine).

For patients searching treatment and pricing details of similar hormone-related therapies, Aggramed injection, also referred to as inj Aggramed or Aggramed inj, is another prescribed option for certain conditions. If considering this, it is advisable to check with your healthcare provider about its suitability and the Aggramed inj price before use

Uses

  • Prostate cancer

  • Hormone-responsive breast cancer in perimenopausal (around menopause) women

  • Endometriosis (a painful illness in which the tissue that normally lines the inside of the uterus grows outside of your uterus)

  • Central precocious puberty (a child’s body begins to change into an adult too soon caused by a release of certain hormones).

How Prolemax 11.25mg Injection works 

Prolemax 11.25mg Injection decreases testosterone or estrogen production, depending on the treated condition. This helps to slow the growth of cancer cells, reduce the size of uterine fibroids, and alleviate the symptoms of endometriosis and early onset of puberty.

Interaction of Prolemax 11.25mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications such as Quinidine, Procainamide, Amiodarone, Sotalol, Painkillers, and Antibiotics may interact with the effects of Prolemax 11.25mg Injection and reduce its effectiveness by causing undesirable side effects.

Storage conditions

  • Keep Prolemax 11.25mg Injection out of sight and reach of children.

  • Store in a cool, dry place, away from direct heat and light.

  • Store below 25oC

  • Do not refrigerate or freeze.

How to use Prolemax 11.25mg Injection

Prolemax 11.25mg Injection is usually administered in the arm, thigh or abdomen. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Safety Advices

Pregnancy-Consult Your Doctor

Pregnancy

Consult Your Doctor

It is unsafe to use Prolemax 11.25mg Injection because it is contraindicated in pregnant women. Tell your doctor if you are pregnant or planning to get pregnant before taking this treatment. 

Breast Feeding-Consult Your Doctor

Breast Feeding

Consult Your Doctor

Prolemax 11.25mg Injection is contraindicated in breastfeeding women. Inform your doctor if you are breastfeeding before taking this injection. 

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

Inform your doctor if you experience any pulmonary embolism, shortness or difficulty of breath, or other underlying lung conditions; consult your doctor for more information.

Liver-Consult Your Doctor

Liver

Consult Your Doctor

Prolemax 11.25mg Injections should be used cautiously in patients with liver impairment. Consult your doctor before receiving it. Notify your doctor about underlying liver conditions. 

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

Consuming alcohol during the Prolemax 11.25mg Injection treatment may increase the risk of thinning bones (osteoporosis). Hence, caution should be taken. Consult your doctor for more information.  

Driving-Unsafe

Driving

Unsafe

Prolemax 11.25mg Injection can cause drowsiness, visual disturbances, or dizziness. It is unsafe; hence, avoid driving if you are unwell.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

  • Severe rash, itching

  • Shortness or difficulty of breath

  • Cough with blood

  • Pulmonary embolism

  • Severe headache

Common

  • Altered blood sugar and cholesterol levels

  • Injection site reactions

  • Loss of appetite

  • Abnormal liver function

  • Swelling in ankle or hand

  • Difficulty sleeping, headache

  • Mood swings, depression

  • Weight changes

  • Nausea, vomiting

  • Vaginal dryness, bleeding

  • Loss of interest in sexual intercourse

  • Hot flushes

  • Bone pain, muscle weakness

  • Breast tenderness.

Expert Tips

  • Regular checkups every three months are recommended during breast cancer treatment with an aromatase inhibitor.

  • Do not receive this injection if you experience abnormal vaginal bleeding.

  • Consult your doctor immediately if you or your child has persistent headaches (even after using painkillers), vision problems, buzzing, or ringing in the ear.

  • If you have diabetes, ask your doctor to monitor your glucose and blood sugar levels regularly.

  • Inform your doctor if you are still menstruating before starting the treatment.

FAQs

Q1.

What is the mechanism of action of Prolemax 11.25mg Injection?

Prolemax 11.25mg Injection decreases testosterone or estrogen production, depending on the treated condition. This helps to slow the growth of cancer cells, reduce the size of uterine fibroids, and alleviate the symptoms of endometriosis and early onset of puberty.

Q2.

Who should not use Prolemax 11.25mg Injection?

Prolemax 11.25mg Injections should not be used by pregnant and breastfeeding women, people who are allergic to the medication, or people with a history of osteoporosis or bone fractures. It should also be used cautiously in people with a past of depression or mental illness.

Q3.

What should I do if I miss a dose of Prolemax 11.25mg Injection?

If you miss a dose of Prolemax 11.25mg Injection, contact your healthcare provider as soon as possible to schedule the missed dose. Do not double up on doses to make up for a missed one.

Q4.

Can Prolemax 11.25mg Injection cause weight gain?

Weight gain is not a common side effect of Prolemax 11.25mg Injection, but it may occur in some people.

Q5.

What is the role of Prolemax 11.25mg Injection in endometriosis treatment?

Endometriosis is a condition where the tissue that lines the uterus grows outside of it, which can cause pain and other symptoms. Prolemax 11.25mg Injection decreases estrogen production, contributing to endometriosis tissue growth. By reducing estrogen levels, Prolemax 11.25mg Injection can help alleviate the symptoms of endometriosis.

Fact Box

Molecule name

Leuprolide acetate 

Therapeutic class

Antineoplastics

Pharmacological class

Gonadotropin-Releasing Hormone (GnRH) agonists 

Indication: 

1. Prostate cancer

2. Hormone-responsive breast cancer in perimenopausal (around menopause) women

3. Endometriosis

4. Central precocious puberty 

 

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Introduction to Endocrinology: The hypothalamic-pituitary axis, 12th edition, 2011, 1122.

  2. KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormones, 7th edition, 2013, 243.

  3. Takeda UK Limited, Electronic medicines compendium (emc), [ Revised on June 2022] [ Accessed on 12th April 2023], https://www.medicines.org.uk/emc/product/4651/smpc  

  4. Abbott Laboratories, US Food and Drug Administration, [Issued on  Feb 2016] [ Accessed on 12th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020517s036_019732s041lbl.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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