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Prolia 60mg Injection

Prescription Required
Cold Chain Required
denosumab

15388

MRP: 19687.5

(You Save ₹4299.5)

1 PREFILLED SYRINGE(s) OF 1ML

Prolia 60mg Injection contains denosumab, a monoclonal antibody used to treat osteoporosis and bone loss associated with certain cancers. It works by inhibiting osteoclast activity, reducing bone resorption and fracture risk. The injection is given subcutaneously under physician guidance.

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Prolia 60mg Injection
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15388

MRP: 19,687.50

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1 Prefilled Syringe(s) Of 1ml

1 Prefilled Syringe(s) Of 1ml

15388.0/Unit
Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
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Salt Composition

DENOSUMAB

Marketer

DR REDDY'S LABORATORIES LTD

Prepaid Only. Non-Returnable.

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Introduction

Prolia 60mg Injection consists of the active ingredient Denosumab. It is mainly prescribed for treating osteoporosis, a condition characterized by weakened bones. Doctors also recommend Prolia injection for osteoporosis in postmenopausal women to reduce the risk of fractures. Additionally, it is used to prevent bone complications in patients with certain cancers, such as multiple myeloma and bone metastases.

Prolia 60mg Injection works by inhibiting a protein called RANK ligand, which is involved in the breakdown of bone tissue. By blocking this process, it helps increase bone density and strength. Clinical studies have shown that it can significantly improve bone health, reducing the chances of fractures in patients with osteoporosis and those with cancer-related bone loss.

Patients may need close monitoring of kidney function, especially if they have moderate renal impairment. The Prolia 60mg dosage should always be taken as directed by your doctor. If you are considering alternatives, your physician may suggest a suitable Prolia 60mg substitute depending on your condition.

When it comes to affordability and availability, patients often compare the Prolia 60mg injection price and the Prolia injection cost in India before starting treatment. Many reliable pharmacies allow you to buy Prolia 60mg online, making access more convenient. Reading Prolia injection reviews may also help patients understand the experiences of others undergoing this treatment. Prolia 60mg Injection Price in India varies by retailer and location.

Uses

Prolia Injection 60mg Uses are in the following condition:

  • Osteoporosis
  • Bone loss due to hormonal therapy in breast or prostate cancer
  • Multiple myeloma (cancer affects plasma cells in the bone marrow)
  • Bone metastases (cancer that spreads to bone)

How Prolia 60mg Injection works

Prolia 60 mg Injection has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.

Interaction of Prolia 60mg Injection with other drugs

Inform the doctor about all the medicines, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Prolia 60mg Injection and reduce effectiveness by causing undesirable side effects.

Storage conditions

  • Prolia 60mg Injection should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).
  • Do not freeze it.
  • Keep in the original package.
  • Keep away from light, moisture, and heat.
  • Keep away from children and pets.
  • Avoid taking double doses for missed doses.

How to use Prolia 60mg Injection

Prolia 60mg Injection is given as an injection by healthcare professionals. The Prolia 60mg Injection dosage and duration of treatment will be based on the individual's condition and response to the medication and should be determined by a healthcare provider.

Safety Advice for Prolia 60mg Injection

Breast Feeding-Consult your doctor

Breast Feeding

Consult Your Doctor

Whether Prolia 60mg Injection is excreted in milk is unknown. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.

Alcohol-unsafe

Alcohol

Unsafe

It is generally recommended to avoid or limit alcohol consumption while taking Prolia 60mg Injection. Alcohol can interact with this medication, potentially increasing the risk of side effects.

Liver-Consult your doctor

Liver

Consult Your Doctor

Prolia 60mg Injection is primarily metabolized in the liver, and its safety has not been extensively studied in individuals with severe liver impairment. It is crucial to communicate any pre-existing liver conditions or changes in liver function to your healthcare provider to ensure this medication's safe and effective use.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

If you have a lung or respiratory disorders history, it is important to consult your healthcare provider before taking Prolia 60mg Injection.

Driving-unsafe

Driving

Unsafe

Patients receiving Prolia 60mg Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely. 

Pregnancy-Consult your doctor

Pregnancy

Consult Your Doctor

The safety of using Prolia 60mg Injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.

Side Effects

Prolia 60mg Side Effects, like all medications, may occur in some people, although not everyone who takes it will experience them. Prolia 60mg side effects are 

Serious:

  • Osteonecrosis of the jaw (severe necrosis or death of jaw cells)
  • Atypical femoral fractures
  • Hypocalcemia (low blood calcium levels)

Common: 

  • Injection site reactions
  • Back pain
  • Musculoskeletal pain
  • Infections
  • Abdominal pain
  • Headache
  • Hypophosphatemia (low blood phosphate levels)

Expert Tips

  • Attend all scheduled appointments and follow-up visits to monitor your response to treatment and manage any concerns or side effects.

  • Inform your doctor about your medical history, including previous infections, liver disease, and kidney disease.

  • Tell your healthcare provider about any allergies or hypersensitivity reactions you may have.

  • Seek immediate medical help if you experience severe allergic reactions or other serious side effects.

  • Prolia 60mg Injection may affect calcium levels; regular monitoring and ensuring adequate calcium and vitamin D intake is important.

  • Pregnant and breastfeeding women should consult a doctor before using this medicine.

  • Avoid taking vaccines while on treatment.

  • Regular dental check-ups and maintaining good oral hygiene are recommended to lower the risk of jaw osteonecrosis.

FAQs about Prolia 60mg Injection

Q1.

Can Prolia 60mg Injection be used in patients with a history of cancer?

Prolia 60mg Injection is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.

Q2.

Can Prolia 60mg Injection be used in patients with kidney problems?

Prolia 60mg Injection is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.

Q3.

Can Prolia 60mg Injection be used as a treatment for osteoporosis in men?

Yes, Prolia 60mg Injection is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.

Q4.

Can Prolia 60mg Injection be used in children and adolescents with osteoporosis?

Prolia 60mg Injection is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.

Q5.

Can Prolia 60mg Injection be used in individuals with dental implants?

Prolia 60mg Injection use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Suppose you have dental implants or are considering getting them. In that case, it is important to discuss this with your dentist and healthcare provider to assess Prolia 60mg Injection's potential risks and benefits.

Q6.

What Are the Side Effects of Prolia 60mg Injection?

Prolia 60mg Injection can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.

Fact Box of Prolia 60mg Injection

Molecule name

Denosumab

Therapeutic class

Anti-resorptive agent

Pharmacological class

Monoclonal Antibodies

Indications: 

1. Osteoporosis

2. Bone loss due to hormonal therapy in breast or prostate cancer

3. Multiple myeloma 

4. Bone metastases 

References

  1. Amgen Ltd, Electronic medicines compendium (EMC), [ Revised on 13th May 2023], [ Accessed on 31st May 2023],https://www.medicines.org.uk/emc/files/pil.568.pdf
  2. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2010] [ Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/125320s007lbl.pdf 
  3. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2022] [ Accessed on 31st May 2023], https://www.fda.gov/media/163378/download

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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Author Details
Dr. Archana Gupta

Written By

Dr. Archana Gupta

BDS

Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS

Last updated : 31 Mar 2026 | 09:31 AM (IST)

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