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Rexigo 120mg Tablet
Last updated on 31 Mar 2026 | 09:30 AM (IST)
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Rexigo 120 mg Tablet is a prescription medicine used to treat advanced prostate cancer in adult men. It contains relugolix, which lowers testosterone levels to help slow cancer progression. Rexigo is used under oncologist supervision as part of hormone-based prostate cancer treatment.
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Introduction to Rexigo 120mg Tablet
Rexigo 120mg Tablet contains Relugolix, a medicine used to treat adult men with advanced hormone-sensitive prostate cancer. It belongs to a group of medications called gonadotropin-releasing hormone (GnRH) receptor antagonists, which work by reducing the levels of testosterone, a hormone that fuels the growth of prostate cancer cells.
By lowering testosterone production, Rexigo 120mg helps slow down or stop the spread of prostate cancer. This can also reduce symptoms such as difficulty in urination or pain associated with the disease. The treatment is taken orally and offers an alternative to injections or surgical options used for testosterone suppression.
Uses of Rexigo 120mg Tablet
Rexigo 120 mg Tablet Uses :
- Treatment of advanced hormone-sensitive prostate cancer.
How Rexigo 120mg Works
Rexigo 120mg Tablet works by blocking the GnRH receptors in the pituitary gland. This action reduces the release of two hormones: luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which leads to a significant drop in testosterone levels. Since testosterone promotes the growth of prostate cancer cells, lowering its levels helps slow the progression of the disease.
Interaction of Rexigo 120mg Tablet with other drugs
Inform your doctor about all medications you are currently taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements. Some drugs may reduce the effectiveness of Rexigo or increase the risk of side effects. Medications that affect P-glycoprotein (P-gp) or CYP enzymes may particularly interact with Relugolix. It’s important to avoid using this medicine along with drugs that prolong QT intervals unless advised by your doctor.
More Information about Rexigo 120mg Tablet
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Store in a cool, dry place below 25°C
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Keep the medicine in its original packaging, away from moisture and light
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Keep out of reach of children
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Do not share this medication with others
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Complete the full course as prescribed by your doctor.
How to take Rexigo Tablet
Take the Rexigo 120mg tablet as your physician advises. Usually, the tablets will be taken with or without food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Safety Advice for Rexigo 120mg Tablet
Breast Feeding
This medicine is not intended to be used in breastfeeding women. Consult your doctor for further information.
Alcohol
Individuals are cautious while consuming alcohol if they are under Rexigo 120mg tablet medication. Consult your doctor before using the medicine.
Liver
Individuals who have liver problems are recommended to discuss with their doctor in order to avoid the adverse effects caused by the drug.
Lungs
It is unknown whether Rexigo 120mg tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
It is unknown whether Rexigo 120mg tablet alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Pregnancy
This medicine is not intended to be used in pregnant women. It might cause harm to the unborn baby during the pregnancy.
Side Effects of Rexigo 120mg Tablet
Rexigo 120 mg tablet side effects are caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common side effects include:
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Hot flushes
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Fatigue or weakness
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Muscle, joint, or bone pain
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Increased blood sugar or fat levels
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Decreased hemoglobin (anemia)
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Constipation or diarrhea
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Headache, nausea
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Increased liver enzymes
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Low libido, erectile issues
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Weight gain
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Breast swelling or tenderness in men (gynecomastia)
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Sleep disturbances, mood changes
Let your doctor know if any of these symptoms persist or worsen. Serious allergic reactions or heart rhythm changes are rare but require immediate medical attention.
Expert Tips
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Take Rexigo at the same time each day for consistent results.
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Stay well hydrated and eat a fibre-rich diet to manage constipation.
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Avoid missing doses. If you do, take it as soon as you remember (within 12 hours); otherwise, skip the missed dose.
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Regularly monitor your PSA levels, blood sugar, blood pressure, and liver function during treatment as advised by your doctor.
FAQs about Rexigo 120mg Tablet
Q1.
Do we need to monitor any parameters during the Rexigo 120mg tablet medication?
Yes, your doctor might recommend that you monitor the treatment progress by PSA (prostate-specific antigen) test.
Q2.
Can I go for a lab test while under Rexigo 120mg tablet medication?
Inform your doctor if you're going to take a blood or liver test. The medicine can alter the blood and liver test report during the lab test.
Q3.
Is there any specific diet I need to follow under the Rexigo 120mg tablet medication?
No, there is no specific diet while under medication. However, avoiding junk foods and eating fiber-rich foods is recommended to manage the constipation caused by the Rexigo 120mg tablet.
Q4.
Is there Rexigo 120mg tablet medication that may cause infertility in males?
Inform your doctor if you are trying to become a father or use an effective contraceptive while under medication; it may cause fertility problems in males.
Q5.
Can I take Rexigo 120mg tablet if I am allergic to sodium?
Consult your doctor if you have an allergy to Rexigo 120mg tablet, sodium, or any of the ingredients present in them. Consult your doctor for further details.
Fact Box of Rexigo 120mg Tablet
Molecule name: Relugolix | Therapeutic class: Androgen suppressor |
Pharmacological class: Gonadotropin-releasing hormone antagonists | Indications: Advanced hormone-sensitive prostate cancer |
Dosage form: Tablet | Habit forming: No |
References
- Accord Healthcare Polska Sp.z o.o., European Medicines Agency (EMA), [Revised on April 2022], [Accessed 06 Mar 2024], https://www.ema.europa.eu/en/documents/product-information/orgovyx-epar-product-information_en.pdf
- Bushu Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [Revised on Dec 2020], [Accessed 06 Mar 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/214621s000lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that experts, accurate and trustworthy, review. The information and contents of this website are for informational purposes only. They are not intended to substitute for professional medical advice, diagnosis, or treatment. Please seek your doctor's advice and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Sakshi Anil More
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)

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