Rybelsus 7mg Tablet is used for:

• Type 2 diabetes mellitus: It helps improve blood sugar control in adults with type 2 diabetes when used along with diet and exercise.

• Additional blood sugar control: It may be used alone when metformin is not considered appropriate or together with other diabetes medicines, depending on the treatment plan prescribed by your doctor.

Rybelsus is not indicated for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

Rybelsus 7mg Tablet contains Semaglutide, which acts like GLP-1, a natural hormone involved in blood sugar regulation.

It helps the pancreas release insulin when blood glucose levels are high and reduces the release of glucagon, a hormone that raises blood glucose. Semaglutide also slows stomach emptying and can reduce appetite, which may affect food intake.

These effects help lower blood glucose levels in people with type 2 diabetes.

Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, supplements and herbal products you take.

• Insulin and sulfonylureas: Using Rybelsus with insulin or a sulfonylurea can increase the risk of low blood sugar. Your doctor may adjust the dose of these medicines.

• Other oral medicines: Rybelsus can delay stomach emptying and may affect the absorption of medicines taken by mouth. Other oral medicines should generally be taken at least 30 minutes after Rybelsus.

• Levothyroxine: Semaglutide may increase exposure to levothyroxine. Your doctor may monitor thyroid-related parameters when these medicines are used together.

• Warfarin and other coumarin medicines: Closer monitoring of blood clotting may be needed when Semaglutide is started in people taking warfarin or similar medicines.

• Other Semaglutide-containing medicines or GLP-1 receptor agonists: Do not use Rybelsus together with another Semaglutide-containing medicine or GLP-1 receptor agonist unless specifically prescribed by your doctor.

• Store Rybelsus 7mg Tablet in its original blister packaging to protect it from light and moisture.

• Store below 30°C.

• Keep the tablets in a dry place.

• Keep Rybelsus 7mg Tablet out of the sight and reach of children.

• Do not use the tablets after the expiry date printed on the packaging.

Take Rybelsus 7mg Tablet exactly as prescribed by your doctor.

Rybelsus should be taken once daily on an empty stomach after an overnight fasting period of at least 8 hours. Swallow the tablet whole with a small amount of plain water, up to half a glass (120 mL). Do not split, crush or chew the tablet.

After taking Rybelsus, wait at least 30 minutes before eating, drinking or taking any other oral medicine. Taking food, other drinks or oral medicines sooner can reduce the absorption of Semaglutide.

Rybelsus 7mg Tablet is generally used after taking the 3mg strength once daily for one month. If additional blood sugar control is needed after at least one month on 7mg, your doctor may increase the dose to 14mg.

Do not change the dose or stop treatment without medical advice.

If you miss a dose, skip it and take your next dose on the following day as usual. Do not take two tablets to make up for a missed dose.

Common side effects of Rybelsus 7mg Tablet may include:

• Nausea

• Diarrhoea

• Vomiting

• Abdominal pain

• Constipation

• Decreased appetite

• Indigestion

• Headache

• Dizziness

Nausea, diarrhoea and vomiting are more common when treatment is started or the dose is increased. These effects are often mild to moderate and may become less troublesome as treatment continues.

Serious side effects

Seek medical attention if you develop:

• Severe or persistent abdominal pain, particularly if it spreads to the back, which may indicate pancreatitis.

• Severe allergic reactions such as swelling of the face, lips, tongue or throat or difficulty breathing.

• Persistent vomiting or diarrhoea that may cause dehydration and affect kidney function.

• Severe abdominal pain, fever or yellowing of the skin or eyes, which may indicate gallbladder disease.

• New or worsening vision changes, particularly if you have diabetic retinopathy.

• Symptoms of low blood sugar, especially when Rybelsus is used with insulin or a sulfonylurea.

• Take Rybelsus 7mg Tablet exactly as prescribed by your doctor.

• Take the tablet on an empty stomach with only a small amount of plain water.

• Wait at least 30 minutes before eating, drinking or taking other oral medicines.

• Swallow the tablet whole. Do not crush, chew or split it.

• Do not take two tablets in one day to make up for a missed dose.

• Do not increase from 7mg to 14mg unless your doctor advises you to do so.

• Tell your doctor if you have a history of pancreatitis, diabetic retinopathy or severe stomach problems.

• Drink enough fluids, particularly if you develop vomiting or diarrhoea.

• Tell your healthcare team that you take Rybelsus before surgery or a procedure involving general anaesthesia or deep sedation.

• If you use insulin or a sulfonylurea, follow your doctor's advice about blood glucose monitoring and dose adjustments.

• Do not change the dose or stop Rybelsus without speaking to your doctor.