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Samvec 10mg Injection
Salt Composition : Vecuronium Bromide
Manufacturer : SAMARTH LIFE SCIENCES PVT LTD
Origin of Medicine : India
Introduction to Samvec 10mg Injection
Samvec 10mg injection contains the active substance vecuronium bromide, which belongs to a class of medicines called skeletal muscle relaxants. It is administered as an adjuvant to general anesthesia to prepare you for surgery. This medication assists in maintaining your body still by relaxing your skeletal muscles during the surgical procedure. It also facilitates the relaxation of the throat, making it easier to insert a breathing tube (endotracheal intubation) before surgery. This medication is used as a muscle relaxant in almost all age groups, including adults, adolescents (2-17 years), newborns, and infants (0 days – 23 months). It is also employed to aid in emergency airway management (mechanical ventilation) for patients in intensive care.
Before receiving samvec 10mg injection, it is crucial to discuss the following with your healthcare team: any prior allergies to vecuronium bromide or other muscle relaxants, reduced renal function or renal disease, heart or circulatory conditions, fluid accumulation, liver or gallbladder issues, edema (swelling of ankles), diseases affecting nerves and muscles such as polio, myasthenia gravis or Eaton-Lambert syndrome. Transparent communication about your medical history is essential for a safe and effective treatment plan.
Uses of Samvec 10mg Injection
An adjuvant to general anesthesia during surgery for
- Skeletal muscle relaxation
- Facilitate endotracheal intubation
- Mechanical ventilation
Therapeutic Effects of Samvec 10mg Injection
When your nerves want your muscles to move, they release a messenger called acetylcholine. This acetylcholine fits into special receptors on your muscle cells, triggering the muscles to contract. When samvec 10mg is present, it blocks this messenger, preventing the muscles from receiving the signal to contract and keeps them relaxed.
Interaction of Samvec 10mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with samvec 10mg injection and cause undesirable side effects.
More Information about Samvec 10mg Injection
- Store samvec 10mg injection below 25°C.
- Protect from light.
- Keep out of reach of children.
- Do not use it after the expiry date.
How to consume Samvec 10mg Injection
This medicine is given only in a hospital setup by a healthcare provider. samvec 10mg will be given to you by your doctor. It is given intravenously (into a vein), either as single injections or as a continuous infusion (a drip). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.
Safety Advices for Samvec 10mg Injection
It is unknown whether samvec 10mg injection can cause fetal harm during pregnancy. Tell your physician if you are pregnant, planning to get pregnant, or think you may get pregnant. However, this medication may be given to you if you have a Caesarean section.
It is unknown whether this injection is excreted in human breast milk. Hence, tell your doctor if you are breastfeeding before taking samvec 10mg injection.
It is unknown whether samvec 10mg injection is safe for persons suffering from lung disease. Inform your doctor if you have any lung disease before starting the treatment.
Prolonged recovery time has been reported when anesthetized along with samvec 10mg injection in patients with liver problems. Inform your doctor if you have any liver disease before starting the treatment.
Generally, it is not recommended to consume alcohol post-surgery with samvec 10mg injection since alcohol can enhance the effect of the injection and delay recovery. We suggest consulting your healthcare provider for further guidance.
Drive or operate machines only when you are told okay. Samvec 10mg injection is used during anesthesia; after it, you might feel tired, weak, or dizzy. Your anesthesia doctor will tell you when it is safe to resume these activities and how long these feelings might last.
Side Effects of Samvec 10mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. If any side effects occur while you are under anesthetic, your doctor will see and treat them.
- Prolonged paralysis (seen in long-term use)
- Bronchospasm/respiratory depression (difficulty breathing)
- Apnea (when you stop breathing)
- Anaphylaxis (sudden allergic reactions)
- Injection site reactions (pain, swelling, and redness)
- Muscle weakness
Word of Advice
This medication is intended for use exclusively within the hospital. Your doctor will administer it during your surgical procedure. While receiving samvec 10mg injection, your doctor will continuously monitor you to assess its impact. It is important to note that this injection induces muscle relaxation, including your breathing muscles. This means you will require assistance with breathing (artificial ventilation) during and after your surgery until you can resume breathing independently. If you have any concerns or questions, always communicate them with your doctor before taking this medication.
Q 1. Is samvec 10mg injection indicated for children?
Yes, samvec 10mg injection is used in adolescents (2-17 years), newborn babies, and infants (0 days – 23 months). However, the dosage may vary from that of adults.
Q 2. Why is samvec 10mg injection used with anesthesia?
Samvec 10mg injection is used with anesthesia to easily place flexible plastic tubes into the trachea (tracheal intubation) and provide skeletal muscle relaxation during surgery.
Q 3. Does samvec 10mg injection cause hypotension/bradycardia?
Samvec 10mg injection can rarely cause hypotension or bradycardia. Inform your doctor right away if you experience one or more such symptoms.
Q 4. Is samvec 10mg injection a sedative?
Samvec 10mg injection is a muscle relaxant and not a sedative. However, it can be used as an additional agent to anesthesia or sedation.
Q 5. Does samvec 10mg injection paralyze the lungs?
Very rarely, prolonged paralysis or respiratory depression is seen with the long-term use of samvec 10mg injection.
Fact Box of Samvec 10mg Injection
Molecule Name: Vecuronium bromide
Therapeutic class: Skeletal muscle relaxants
Pharmacological class: Neuromuscular Blocking Agents
Indications: As an adjuvant to general anesthesia during surgery for
1. Skeletal muscle relaxation
2. Facilitate endotracheal intubation
3. Mechanical ventilation
- Sun Pharma, Electronic medicines compendium (EMC), [Revised on Jun 2019], [Accessed on 25th Sept 2023], https://www.medicines.org.uk/emc/product/2619/smpc
- Ben Venue Laboratories, US Food and Drug Administration (FDA), [Revised on Jul 2018], [Accessed on 25th Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/075549s013lbl.pdf
- Mark Ramzy et al.; Vecuronium, Published on Dec 2022; Accessed on 25/09/2023; https://www.ncbi.nlm.nih.gov/books/NBK493143/
- KD Tripathi, Essentials of Medical Pharmacology, Skeletal muscle relaxants, 8th edition, 2019, 379
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Agents acting at the neuromuscular junction and autonomic ganglia, 13th edition, 2018, 188
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