Semalix 14 Tablet is used for:

• Type 2 diabetes mellitus: It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

• Additional glycaemic control: The 14 mg strength may be prescribed when additional blood sugar control is needed after treatment with 7 mg.

Semalix 14 Tablet contains Semaglutide, which acts like the natural hormone GLP-1. It helps increase insulin release when blood glucose is high and reduces glucagon release.

Semaglutide also slows stomach emptying and increases feelings of fullness. Together, these effects help improve blood sugar control and can reduce food intake.

Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, supplements and herbal products you take.

• Insulin and sulfonylureas: Can increase the risk of low blood sugar when used with Semalix.

• Other oral medicines: Delayed stomach emptying may affect the absorption of some medicines taken by mouth.

• Other Semaglutide-containing medicines: Do not use another Semaglutide medicine with Semalix unless specifically prescribed.

• Other GLP-1 receptor agonists: Do not combine these with Semalix unless advised by your doctor.

• Store Semalix 14 Tablet below 30°C.

• Keep it in its original packaging and protect it from moisture.

• Keep it out of the sight and reach of children.

Take Semalix 14 Tablet exactly as prescribed by your doctor.

• Take it once daily, first thing in the morning on an empty stomach.

• Swallow the tablet whole with a small amount of plain water. Do not split, crush or chew it.

• Take it at least 30 minutes before eating, drinking or taking any other oral medicine.

• The 14 mg strength is generally considered when additional blood sugar control is needed after at least 30 days on 7 mg.

• Do not take two 7 mg tablets to make a 14 mg dose.

• Do not change the dose or stop treatment without medical advice.

• If you miss a dose, skip it and take the next dose on the following day. Do not take two doses together.

Common side effects:

• Nausea

• Abdominal pain

• Diarrhoea

• Decreased appetite

• Vomiting

• Constipation

Gastrointestinal side effects may be more noticeable at higher doses and often occur during dose escalation.

Serious side effects:

• Pancreatitis: Severe or persistent abdominal pain, sometimes spreading to the back.

• Severe gastrointestinal reactions: Persistent vomiting, diarrhoea or severe stomach-related symptoms.

• Hypoglycaemia: Particularly when Semalix is used with insulin or sulfonylureas.

• Acute kidney injury: May occur after significant dehydration caused by vomiting or diarrhoea.

• Diabetic retinopathy complications: New or worsening vision changes.

• Gallbladder problems: Severe abdominal pain, fever or yellowing of the skin or eyes.

• Serious allergic reactions: Swelling of the face, lips, tongue or throat or difficulty breathing.

Seek prompt medical attention if you develop symptoms suggesting a serious reaction.

• Take Semalix 14 Tablet exactly as prescribed.

• Take the tablet with only plain water and wait at least 30 minutes before food or other oral medicines.

• Do not take two 7 mg tablets in place of one 14 mg tablet.

• Monitor your blood sugar as advised by your doctor.

• Tell your doctor if you take insulin or a sulfonylurea.

• Report severe abdominal pain, persistent vomiting or diarrhoea, or changes in vision promptly.

• Tell your doctor before surgery or deep sedation.

• Do not combine Semalix with another Semaglutide-containing medicine or GLP-1 receptor agonist unless specifically prescribed.

• Do not use Semalix if you have a personal or family history of MTC or MEN2.