Quick Summary
Semasize 0.5mg Injection PFS
Last updated on 30 Jun 2026 | 12:44 PM (IST)
₹338
MRP: ₹375
(You Save ₹37)
1 PREFILLED SYRINGE(s) OF 0.38ML
Semasize 0.5mg Injection PFS
Salt Composition
SEMAGLUTIDEMarketer
ALKEM LABORATORIES LTD
Prepaid Only. Non-Returnable.
10% OFF
₹338
MRP: ₹375.00
Inclusive of all taxes
10% Off
Salt Composition
SEMAGLUTIDEMarketer
ALKEM LABORATORIES LTD
Prepaid Only. Non-Returnable.
Dispatch: Today
Order In: 0h 0m 0s
0h 0m 0s
Order before timer ends to ensure your medicine is dispatched at...
Substitutes
Hepaglide 0.5mg Injection
ALKEM LABORATOR...
₹ 427.50/injection
27% costlier
Obesema 0.5mg Injection
ALKEM LABORATOR...
₹ 427.50/injection
27% costlier
Noveltreat 0.5mg Injection
SUN PHARMACEUTI...
₹ 437.75/injection
30% costlier
Semawin 0.5mg Pen injection
INTAS PHARMACEU...
₹ 450.00/injection
34% costlier


Introduction
Semasize 0.5mg Injection PFS composition contains Semaglutide, a GLP-1 receptor agonist that mimics a natural hormone involved in appetite regulation and food intake. Semasize 0.5mg Injection PFS is a once-weekly injectable treatment for adults to support effective and sustainable weight management. Semasize 0.5mg Injection PFS benefits include helping you feel full sooner and stay satisfied longer, supporting healthier eating habits and portion control. Semasize 0.5mg Injection PFS for obesity is one of its primary applications, and weight loss is often observed when semasize 0.5 mg injection pfs is combined with a balanced diet and regular physical activity.
This treatment is commonly recommended for individuals who are overweight or living with obesity, particularly those with associated conditions such as type 2 diabetes, high blood pressure, or high cholesterol. While Semasize 0.5mg Injection PFS is not a rapid solution, it plays an important role in long-term weight management when used consistently and under medical supervision. Your doctor will guide you on the correct Semasize 0.5mg Injection PFS dosage and instructions based on your health profile and treatment goals.
Before starting therapy, consult a healthcare professional who will evaluate your medical history, suitability, and expectations from treatment. Discuss practical aspects such as the Semasize 0.5mg Injection PFS price in India and availability as part of your overall treatment planning. Consult your doctor before switching to any Semasize 0.5mg Injection PFS substitute or Semasize 0.5mg Injection PFS alternative. Check the current price and buy Semasize 0.5mg Injection PFS online at MrMed with pan-India delivery.
Uses
Semasize 0.5mg Injection PFS uses for:
Long-term weight management in adults with obesity (BMI of 30 or more).
Weight management in adults with a BMI of 27 or more who also have weight-related health issues like type 2 diabetes, high blood pressure, or high cholesterol.
How Semasize 0.5mg Injection PFS Works
Semasize 0.5mg Injection PFS for weight loss by mimicking natural hormones that regulate hunger. As a GLP-1 medication, it sends signals to your brain that you are full, helping you feel satisfied after smaller meals. It also slows the movement of food through your stomach, prolonging fullness and reducing cravings.
Semasize 0.5mg Injection PFS influences GIP, another hormone involved in metabolism, which can help improve how your body handles nutrients and supports weight management.
Using a GLP-based approach, such as Semasize 0.5mg Injection PFS, provides consistent appetite control over time. Results appear gradually, allowing you to eat less without feeling deprived, which is essential for sustainable, long-term weight loss.
Interaction of Semasize 0.5mg Injection PFS with other drugs
Before starting Semasize 0.5mg Injection PFS, tell your doctor about all the medicines, supplements, or herbal products you're taking. Some combinations can cause serious side effects, especially affecting your blood sugar, blood pressure, or digestion.
Watch out for interactions with:
Insulin or diabetes pills (like glimepiride or glipizide): These can lower your blood sugar too much when combined with Semasize 0.5mg Injection PFS.
Blood thinners (like warfarin): You may need extra monitoring, as weight loss can change how this medicine works.
Thyroid medication (such as levothyroxine): Rapid weight loss may affect your thyroid levels.
Water pills (diuretics): Combined weight and water loss can lead to dehydration or low blood pressure.
Birth control pills: Semasize 0.5mg Injection PFS might change how well these work if you get nauseous or vomit often.
Also, avoid taking other weight-loss drugs or similar injections unless your doctor says it's okay.
Storage Conditions
Store your pen in the fridge (not the freezer), it should be kept between 2°C and 8°C.
If you forget a dose, take it within 5 days. If it’s been longer than 12 hours, skip that dose and stick to your regular schedule.
Never take two doses at once to make up for a missed one.
Signs of overdose (like severe nausea or vomiting) need medical attention right away.
Always keep the pen out of children’s reach and don’t share it, even if the needle is changed.
How to use Semasize 0.5mg Injection PFS
Semaglutide 0.25mg Injection PFS, a GLP-1–based medication, is given once weekly as a subcutaneous injection. You can inject it into your stomach, thigh, or upper arm; just rotate injection sites to avoid irritation. It can be taken with or without food.
For consistent results, use it on the same day each week. Your doctor or nurse will guide you on how to use this injection pen safely, ensuring proper technique and effectiveness.
Safety advice
Pregnancy
Semasize 0.5mg Injection PFS is not safe during pregnancy. If you're planning to get pregnant, you'll need to stop this medication at least 2 months before trying.
Breast Feeding
If you are breastfeeding, consult your healthcare provider before using Semasize 0.5mg Injection PFS, as its efficacy and safety in breastfeeding are unknown.
Lungs
Semasize 0.5mg Injection PFS doesn’t directly affect your lungs. If you have asthma or another lung issue, it’s still safe, but your doctor should be in the loop.
Liver
People with liver issues may still be able to take Semasize 0.5mg Injection PFS, but some extra care and monitoring might be needed.
Alcohol
Drinking alcohol while using Semasize 0.5mg Injection PFS can increase your risk of stomach issues or low blood sugar, especially if you’re diabetic.
Driving
Semasize 0.5mg Injection PFS doesn’t usually affect your ability to drive. But if you feel dizzy, tired, or unwell after the shot, skip driving that day.
Side Effects
Semasize 0.5mg Injection PFS side effects, like all medications, although not everyone will experience them. Semasize 0.5mg Injection PFS side effects are
Common side effects:
Nausea
Vomiting
Constipation or diarrhoea
Tiredness
Headache
Indigestion
Bloating or gas
Serious side effects (get medical help if you notice these):
Severe stomach pain or signs of pancreatitis
Gallbladder issues (like pain in your upper belly or yellowing of the skin)
Signs of kidney problems (such as less urination or swelling)
Fast heart rate
Allergic reactions (rash, itching, swelling, trouble breathing)
Expert Tips
Stick to a Weekly Routine: Take Semasize 0.5mg Injection PFS on the same day each week. Use phone reminders or calendar alerts to avoid missing a dose.
Rotate Injection Sites: To prevent skin irritation or lumps, inject into different spots on your abdomen, thigh, or upper arm each time.
Manage Nausea Smartly: Eat small, balanced meals and avoid greasy or high-fat foods. This can help reduce nausea and improve digestion.
Stay Hydrated: Drink plenty of water throughout the day to prevent dehydration, especially if you experience nausea, vomiting, or diarrhoea.
Watch for Warning Signs: If you notice severe stomach pain, vomiting, or signs of an allergic reaction, seek medical help immediately. These could be signs of serious side effects, such as pancreatitis.
FAQs
Q1.
What is Semasize 0.5mg Injection PFS used for?
Semasize 0.5mg Injection PFS is used to help adults lose weight and keep it off. It’s meant for people who are overweight or obese and may have health issues like high blood pressure or type 2 diabetes. This dose is the starting point in the treatment plan to help your body get used to the medication.
Q2.
When will I start seeing results with Semasize 0.5mg Injection PFS?
Some people feel less hungry within the first week or two. Real weight loss usually becomes noticeable after a month or more, especially as your dose increases and you stick to healthy eating and exercise habits.
Q3.
Can I take Semasize 0.5mg Injection PFS with other weight-loss medicines?
Generally, you should not combine Semasize 0.5mg Injection PFS with other weight-loss drugs or injections unless your doctor approves. Mixing treatments could lead to unwanted side effects or interactions.
Q4.
What should I do if I miss a Semasize 0.5mg Injection PFS?
If you miss a dose, take it within 5 days of the missed day. If it’s been more than 5 days, skip that dose and wait until your next scheduled one. Don’t double up. Set reminders so you don’t forget next time!
Q5.
Is Semasize 0.5mg Injection PFS a GLP-1 medication, and how does it work?
Yes, Semasize 0.5mg Injection PFS is a GLP-1 receptor agonist. It works by mimicking a natural hormone in your body that helps regulate appetite and blood sugar levels. This helps you feel full sooner, eat less, and reduce cravings, which supports gradual and sustainable weight loss.
Fact Box
Molecule name | Semaglutide |
Therapeutic class | Weight management medicine |
Pharmacological class | GLP-1 receptor agonist |
Indications | Long-term weight loss in adults with obesity or overweight with related health problems |
References
Novo Nordisk Inc, FDA Food and Drug Safety Administration [September 20, 2019] [Accessed date 18th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/209637s032lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
Did you find this information helpful?
Author Details

Written By
Dr. Vikas B S
Pharm D

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 30 Jun 2026 | 12:44 PM (IST)

Want to know more?
Read Our Editorial Policy








