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Tefowell AF Tablet
Last updated on 06 Aug 2026 | 06:08 AM (IST)
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30 TABLET(s) IN A BOTTLE
Tefowell AF Tablet is an antiviral medicine used to treat chronic hepatitis B infection by reducing the amount of hepatitis B virus in the body and protecting the liver from further damage. It helps improve long term liver health. Common side effects include headache, nausea, fatigue, abdominal pain, and diarrhea.
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Introduction
Tefowell AF Tablet is an antiviral medication containing the active constituent tenofovir alafenamide. Tefowell AF Tablet uses include the treatment of chronic hepatitis B virus (HBV) infection. Hepatitis B is a liver infection caused by the hepatitis B virus, and tefowell af helps reduce viral activity and protect the liver from further damage. The benefits of Tefowell AF Tablet include improved liver health, reduced viral replication, and long term management of chronic hepatitis B infection.
The composition of Tefowell AF Tablet includes tenofovir alafenamide, which is also considered the generic name of Tefowell AF Tablet. Patients searching for Tefowell AF Tablet price in India should note that prices may vary depending on the pharmacy, brand availability, and location. Individuals planning to buy Tefowell AF Tablet online should purchase only from trusted pharmacies with a valid prescription. Patients looking for a substitute for Tefowell AF Tablet should consult their healthcare provider for appropriate antiviral alternatives.
Discuss with your doctor about the necessary precautions to avoid spreading hepatitis B infection to others. Inform your doctor if you have kidney disease, liver disease, or HIV infection before starting treatment with tefowell af. Use of this medicine may sometimes lead to lactic acidosis (excess acid buildup in the blood) and hepatomegaly (enlarged liver).
This medicine is not recommended for patients weighing less than 35 kg. Tefowell AF Tablet contains lactose, so patients with sugar intolerance should consult their doctor before use. Tell your healthcare provider if you are pregnant or breastfeeding before taking this medicine. Do not stop taking Tefowell AF Tablet without medical advice, as sudden discontinuation may worsen hepatitis B infection.
The dosage of Tefowell AF Tablet depends on the patient’s medical condition, liver function, and physician recommendation. Dosage adjustments and careful monitoring may be required in children and elderly patients. Common side effects of Tefowell AF Tablet may include headache, nausea, fatigue, abdominal pain, diarrhea, and dizziness.
Uses
Tefowell AF Tablet is used in the treatment of:
Hepatitis B virus (HBV) infection.
HIV-1 Infection.
How Tefowell AF Tablet Works
Its therapeutic effect of Tefowell AF Tablet involves reducing viral replication, lowering a viral load, preserving the immune system, and delaying disease progression in individuals with HIV-1 or HBV.
Interaction of Tefowell AF Tablet with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Tefowell AF Tablet, reducing effectiveness by causing undesirable side effects.
Storage Conditions
Store Tefowell AF Tablet at a temperature between 20°C to 25°C (68°F to 77°F).
Keep away from moisture, heat, and light.
It should not be frozen.
Keep it in its original packaging.
Keep away from children and pets.
How to take Tefowell AF Tablet
To consume Tefowell AF Tablet properly, follow your healthcare provider's instructions regarding dosage, frequency, and duration. Take it with or without food, swallowing the tablets or capsules with water. Adhere to the prescribed dosing schedule; do not alter the dosage without consulting your healthcare provider.
Safety advice
Pregnancy
If you are pregnant or planning to become pregnant, it is crucial to consult with your healthcare provider before taking Tefowell AF Tablet.
Breast Feeding
Tefowell AF Tablet is excreted into human breast milk, but the potential risks to the infant are not well established. So it is better to consult a doctor before taking it.
Lungs
If you have a history of lung disease or are experiencing respiratory symptoms while taking, it is important to consult your healthcare provider for a thorough evaluation before taking Tefowell AF Tablet.
Liver
The safety of Tefowell AF Tablet in individuals with liver disease may depend on the specific type and severity of liver disease and other factors. It is important to consult with a healthcare provider
Alcohol
It is generally recommended to avoid excessive alcohol consumption while taking Tefowell AF Tablet or any medication. Alcohol can interact with this medication and affect liver function.
Driving
People may experience side effects such as dizziness, drowsiness, or fatigue while taking Tefowell AF Tablet. Suppose you experience any of these side effects or any other symptoms that may interfere with your ability to drive safely. In that case, avoid driving or operating heavy machinery.
Side Effects
Tefowell AF Tablet causes some side effects like all medications, although not everyone will experience them.
Serious side effects of Tefowell AF Tablet are:
Too much lactic acid in the blood (unusual weakness, muscle pain, cold hands and feet)
Severe liver problems (yellow skin and eyes, tea-coloured urine, light-coloured stools, loss of appetite)
Severe kidney problems
Common side effects of Tefowell AF Tablet are:
Nausea, vomiting
Diarrhea
Stomach pain, joint pain
Rash, itching
Feeling tired
Headache, dizziness
Expert Tips
If you are considering of taking Tefowell AF Tablet, it is important to be aware of the potential risks and warnings associated with this medication. Pregnancy and breastfeeding require individual evaluation and consultation with a healthcare provider to weigh the benefits against potential risks. It should be used cautiously in individuals with pre-existing conditions such as liver disease, kidney disease, or bone disorders, as it may exacerbate them. Close monitoring and appropriate management are necessary in these cases. Adherence to these precautions and regular monitoring and communication with the healthcare provider can help ensure safe and effective use.
FAQs
Q1.
Can Tefowell AF Tablet be taken with other antiretroviral medications?
Yes, Tefowell AF Tablet is often combined with other antiretroviral medications as part of a multidrug regimen for treating HIV infection. The specific combination of medications will depend on individual health status, treatment history, and potential drug interactions.
Q2.
Can Tefowell AF Tablet cause lactic acidosis?
Although rare, Tefowell AF Tablet has been associated with the risk of lactic acidosis. Lactic acidosis is a serious condition characterised by the buildup of lactic acid in the blood. It is important to promptly report any symptoms such as unusual weakness, rapid breathing, nausea, vomiting, abdominal pain, or unexplained muscle pain to your healthcare provider while taking it.
Q3.
Can Tefowell AF Tablet be taken while undergoing surgery or dental procedures?
If you are scheduled for surgery or dental procedures, informing your healthcare provider or dentist about your Tenofovir alafenamide treatment is important. They can guide whether any adjustments need to be made, such as temporary discontinuation or use of other medications during the procedure.
Q4.
Can Tefowell AF Tablet be used during chemotherapy or radiation therapy?
The use of Tefowell AF Tablet in individuals undergoing chemotherapy or radiation therapy should be evaluated on a case-by-case basis, considering potential drug interactions and individual health factors. It is crucial to consult the HIV specialist and oncologist to determine the most appropriate treatment approach.
Q5.
Can Tefowell AF Tablet cause weight gain?
Weight gain is not a commonly reported side effect of Tefowell AF Tablet. However, individual responses to medications can vary, and some people may experience changes in weight while taking this medication. It is important to discuss any concerns about weight changes with your healthcare provider.
Q6.
Can Tefowell AF Tablet be safely used in older adults?
Tefowell AF Tablet can be used in older adults, but dosage adjustments or additional monitoring may be necessary, as age-related changes in kidney and liver function can affect medication clearance. It is important to discuss individual health status and any concerns with a healthcare provider.
Fact Box
Molecule name | Tenofovir alafenamide |
Therapeutic class | Antiviral agents |
Pharmacological class | Nucleoside reverse transcriptase inhibitors (NRTIs) |
Indications | 1. HIV- 1 Infection 2. Hepatitis B infection |
References
KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 808.
Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Antiviral agents (Non-retroviral), 12th edition, 2011, 1615.
Gilead Sciences Ltd, Electronic medicines compendium (EMC), [ Revised on Jan 2021] [ Accessed on 18th May 2023], https://www.medicines.org.uk/emc/files/pil.2314.pdf
Gilead Sciences, US Food, and Drug Administration, [ Revised on Feb 2020] [ Accessed on 18th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208464s008lbl.pdf
Disclaimer
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Author Details

Written By
Dr. Vikas B S
Pharm D

Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 06 Aug 2026 | 06:08 AM (IST)

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