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Tenvir AF 25mg Tablet
Last updated on 21 Apr 2026 | 06:50 AM (IST)
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30 TABLET(s) IN A BOTTLE
Tenvir AF 25 mg Tablet is a prescription antiviral medicine used in the treatment of HIV-1 infection and chronic hepatitis B. It contains tenofovir alafenamide, which works by inhibiting viral replication and reducing the amount of virus in the body. Tenvir AF is taken under strict medical supervision as part of a long-term antiviral treatment plan.
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Introduction
Tenvir AF 25mg Tablet is an antiviral medication containing the active constituent Tenofovir alafenamide. It is used to treat chronic hepatitis B virus (HBV) infection. Hepatitis B is an infection affecting the liver caused by the hepatitis B virus. Discuss with your doctor about the precautions needed to avoid infecting others. Tell your doctor if you have or have ever had kidney diseases, liver diseases, or HIV before taking Tenvir AF 25mg Tablet. Administration of this medicine may lead to lactic acidosis (accumulation of excessive acid) and hepatomegaly (enlarged liver).
It is not recommended for patients weighing less than 35 kg. This medicine contains lactose. Contact your doctor if you are intolerant to sugars before taking medicine. Tell your doctor if you are breastfeeding or pregnant before taking Tenvir AF 25mg Tablet. Do not stop taking this medicine without your doctor’s advice, as it may worsen the condition. The safety and efficacy of this medication in pediatric patients may differ from those in adults. Dosage adjustments and careful monitoring may be necessary for children and the elderly. Tenvir af 25 mg tablet price based on the location and vendor.
Uses
Tenvir af 25 mg tablet uses :
Hepatitis B virus (HBV) infection
How Tenvir AF 25mg Tablet Works
Its therapeutic effect of Tenvir AF 25mg Tablet involves reducing viral replication, lowering a viral load, preserving the immune system, and delaying disease progression in individuals with HIV-1 or HBV.
Interaction of Tenvir AF 25mg Tablet with other drugs
Taking Tenvir AF 25mg Tablet (tenofovir alafenamide) with any of the following medicines can change the effect of either of them and may increase the risk of side effects.
Rifampicin (Oral Route) Life-threatening
Do not use together.
Concomitant use may significantly reduce the levels of tenofovir alafenamide and make the treatment ineffective.
Carbamazepine, Phenytoin, or Phenobarbital (Oral Route) Life-threatening
Avoid using together.
These medicines may decrease drug levels and lead to treatment failure.
St John’s Wort (Herbal Route) Life-threatening
Do not take together.
This herbal product may reduce the effectiveness of antiviral therapy.
Other antivirals containing Tenofovir (Oral Route) Moderate
Do not use together unless prescribed.
Taking similar medicines together may increase the risk of side effects without added benefit.
Nephrotoxic medicines such as Aminoglycosides or high dose NSAIDs (Oral/Injection Route) Moderate
Use with caution.
Concomitant use may increase the risk of kidney damage.
Anticonvulsants such as Oxcarbazepine (Oral Route) Moderate
Use under medical supervision.
These medicines may reduce the blood levels of tenofovir alafenamide.
Storage Conditions
Store at temprature between 20°C to 25°C (68°F to 77°F).
Keep away from moisture, heat, and light.
It should not be frozen.
Keep it in its original packaging.
Keep away from children and pets.
How to consume Tenvir AF 25mg Tablet
To consume Tab Tenvir AF 25mg properly, follow your healthcare provider's instructions regarding dosage, frequency, and duration. Take it with or without food, swallowing the tablets or capsules with water. Adhere to the prescribed dosing schedule; do not alter the dosage without consulting your healthcare provider.
Safety Advice
Breast Feeding
Tenvir AF Tablet is excreted into human breast milk, but the potential risks to the infant are not well established. So it is better to consult a doctor before taking it.
Alcohol
It is generally recommended to avoid excessive alcohol consumption while taking Tenvir AF 25mg Tablet or any medication. Alcohol can interact with this medication and affect liver function.
Liver
The safety of Tenvir AF 25mg Tablet in individuals with liver disease may depend on the specific type and severity of liver disease and other factors. It is important to consult with a healthcare provider
Lungs
If you have a history of lung disease or are experiencing respiratory symptoms while taking, it is important to consult your healthcare provider for a thorough evaluation before taking Tenvir AF 25mg Tablet.
Driving
People may experience side effects such as dizziness, drowsiness, or fatigue while taking Tenvir AF 25mg Tablet. Suppose you experience any of these side effects or any other symptoms that may interfere with your ability to drive safely. In that case, avoid driving or operating heavy machinery.
Pregnancy
If you are pregnant or planning to become pregnant, it is crucial to consult with your healthcare provider before taking Tenvir AF 25mg Tablet.
Side Effects
Tenvir AF 25mg Tablet causes some side effects like all medications, although not everyone will experience them.
Serious:
Too much lactic acid in the blood (unusual weakness, muscle pain, cold hands and feet)
Severe liver problems (yellow skin and eyes, tea-colored urine, light-colored stools, loss of appetite)
Severe kidney problems
Common:
Nausea, vomiting
Diarrhea
Stomach pain, joint pain
Rash, itching
Feeling tired
Headache, dizziness
Expert Tips
Understand the potential risks and warnings before starting this medicine and discuss them with your doctor.
Pregnancy and breastfeeding require careful evaluation to balance the benefits and possible risks.
Use this medicine with caution if you have liver disease, kidney disease, or bone disorders, as it may worsen these conditions.
Regular monitoring and proper medical management are important during treatment.
Stay in close communication with your healthcare provider to ensure safe and effective use.
FAQs
Q1.
Can Tenvir AF 25mg Tablet be taken with other antiretroviral medications?
Yes, Tenvir AF 25mg Tablet is often combined with other antiretroviral medications as part of a multidrug regimen for treating HIV infection. The specific combination of medications will depend on individual health status, treatment history, and potential drug interactions.
Q2.
Can Tenvir AF 25mg Tablet be safely used in older adults?
Tenvir AF 25mg Tablet can be used in older adults, but dosage adjustments or additional monitoring may be necessary, as age-related changes in kidney and liver function can affect medication clearance. It is important to discuss individual health status and any concerns with a healthcare provider.
Q3.
Can Tenvir AF 25mg Tablet cause weight gain?
Weight gain is not a commonly reported side effect of Tenvir AF 25mg Tablet. However, individual responses to medications can vary, and some people may experience changes in weight while taking this medication. It is important to discuss any concerns about weight changes with your healthcare provider.
Q4.
Can Tenvir AF 25mg Tablet be used during chemotherapy or radiation therapy?
The use of Tab Tenvir AF 25mg in individuals undergoing chemotherapy or radiation therapy should be evaluated on a case-by-case basis, considering potential drug interactions and individual health factors. It is crucial to consult the HIV specialist and oncologist to determine the most appropriate treatment approach.
Q5.
Can Tenvir AF 25mg Tablet be taken during surgery or dental procedures?
If you are scheduled for surgery or dental procedures, informing your healthcare provider or dentist about your Tenvir AF 25mg Tablet treatment is important. They can guide whether any adjustments need to be made, such as temporary discontinuation or use of other medications during the procedure.
Q6.
Can Tenvir AF 25mg Tablet cause lactic acidosis?
Although rare, Tenvir AF 25mg Tablet has been associated with the risk of lactic acidosis. Lactic acidosis is a serious condition characterized by the buildup of lactic acid in the blood. It is important to promptly report any symptoms such as unusual weakness, rapid breathing, nausea, vomiting, abdominal pain, or unexplained muscle pain to your healthcare provider while taking it.
Fact Box of Tenvir AF 25mg Tablet
Molecule name: Tenofovir alafenamide | Therapeutic class: Antiviral agents |
Pharmacological class: Nucleoside reverse transcriptase inhibitors (NRTIs) | Indications: Hepatitis B infection |
References
- KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 808.
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Antiviral agents (Non-retroviral), 12th edition, 2011, 1615.
- Gilead Sciences Ltd, Electronic medicines compendium (EMC), [ Revised on Jan 2021] [ Accessed on 18th May 2023], https://www.medicines.org.uk/emc/files/pil.2314.pdf
- Gilead Sciences, US Food, and Drug Administration, [ Revised on Feb 2020] [ Accessed on 18th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208464s008lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. Archana Gupta
BDS

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 21 Apr 2026 | 06:50 AM (IST)

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