THALIX 50MG CAPSULE

Introduction:

Thalix 50mg Capsule consists of the active ingredient Thalidomide. It is currently used for treating multiple myeloma at initial diagnosis and preventing relapse. 

Multiple myeloma is a type of cancer occurring in the plasma cells of the white blood cells. These plasma cells get accumulated in the bone marrow and divide uncontrollably, leading to damage in bone and kidneys. 

Thalix 50mg Capsule is also prescribed for treating skin lesions in leprosy. Leprosy is a chronic disease that affects the skin and nerves and is caused by a bacteria named Mycobacterium leprae.

Uses of Thalix 50mg Capsule:

• Adjunct to Dexamethasone for the treatment of newly diagnosed multiple myeloma.
• Treatment of moderate to severe leprosy
• Prevention of recurrence of skin lesions in leprosy.

How Thalix 50mg Capsule Works:

Thalix 50mg Capsule reduces inflammation and regulates the immune system. It works by enabling the body’s immune system and attacking the cancer cells. It inhibits tumor necrosis factor-alpha, increases the production of interleukin-10 and interacts with the T-cells to generate an immune response. It halts the growth of blood vessels in cancer cells and arrests their development.

Interaction with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More Information:

Store in a cool, dry place. Protect from light.

References:

1. Celgene Europe B.V, Electronic Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 6th Dec 2021], https://www.medicines.org.uk/emc/files/pil.6317.pdf
2. Celgene Corporation, US Food and Drug Administration, [Revised on Jun 2019] [Accessed on 6th Dec 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020785s067lbl.pdf
3. Douglas F. Lake and Adrienne D. Briggs, Immunopharmacology, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 977-1002.
4. D.H. Dockrell, S. Sundar, B.J. Angus, R.P. Hobson, Infectious Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 293-386.

How to use Thalix 50mg Capsule:

Swallow the capsule whole with water. Wash your skin carefully with soap and water in case of contact with a broken capsule.     

Safety Advice:

Pregnancy:

Thalix 50mg Capsule causes birth defects and the death of the fetus. Inform your physician before taking Thalix 50mg Capsule if you are pregnant or think you might be pregnant.

Breastfeeding: 

Thalix 50mg Capsule passes through breast milk. Consult your physician for advice before breastfeeding.

Liver: 

Inform your physician before taking Thalix 50mg Capsule if you have liver problems.

Kidney:

Inform your physician before taking Thalix 50mg Capsule if you have kidney problems.

Driving:

Avoid driving or doing things that require concentration if you experience any side effects.

Allergies:

Inform your physician right away if you have allergic reactions to Thalix 50mg Capsule or its ingredients

Others:

• Consult your physician and use an effective contraceptive to avoid unwanted pregnancy during this treatment.
• Talk to your physician if you have had a heart attack, blood disorders, high BP or high cholesterol.
• Inform your physician before starting treatment if you have or ever had neuropathy, seizures, skin reactions or severe infections.
• Inform your physician if you smoke or drink alcohol.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

• Nerve damage
• Decreased blood pressure
• Low WBC count
• Slow heartbeat
• Serious allergic reactions
• Tumor lysis syndrome
• Sudden pain in the chest or difficulty breathing
• Pain and swelling of legs
• Bleeding or bruising without injury

Common:

• Sleepiness
• Rashes
• Headache
• Dizziness
• Impotence
• Decreased energy or strength
• Pain
• Tiredness
• Low calcium and blood count levels
• Swelling of hands and feet
• Constipation
• Numbness or tingling
• Nausea and reduced appetite
• Anxiety, depression, confusion and mood swings
• Fever
• Weight loss or weight gain
• Indigestion, vomiting and dry mouth
• Muscle cramps
• Blurred vision
• Chest infection, lung disease
• Ear problems
• Kidney damage