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Trastuneal 150mg Injection

Prescription Required
Cold Chain Required
trastuzumab

3524

MRP: 4699

(You Save ₹1175)

1 VIAL(s)

25% OFF
Trastuneal 150mg Injection
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3524

MRP: 4,699.00

Inclusive of all taxes

25% Off

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1 Vial(s)

1 Vial(s)

3524.0/Unit
Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
Info

Salt Composition

TRASTUZUMAB

Marketer

AMNEAL PHARMACEUTICALS PVT LTD

Prepaid Only. Non-Returnable.

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Introduction

Trastuneal 150mg Injection consists of Trastuzumab as an active constituent, which is indicated for use in HER2 breast cancer. In HER2-positive patients, breast cancer cells are largely composed of HER2 proteins that drive rapid tumor growth by signaling to cancer cells. This medication is also used to treat metastatic gastric cancer with increased levels of HER2 proteins.


HER2-positive breast cancers are most aggressive in nature. The targeted therapy for HER2-positive breast cancer works by selectively targeting the proteins that are responsible for the growth, development, and spread of cancer. Use effective birth control during the treatment and for at least 7 months after the final dose.


Trastuzumab 150 mg injection is not recommended for patients aged under 18, patients who have severe breathing problems or patients who need oxygen treatment. It is necessary to let your physician know if you have any heart problems, breathlessness, or have ever had any other cancer treatment. Inform your physician of all medicines, including supplements and herbal medicines, you are taking before you start treatment with this medication.

Uses

The Trastuneal 150mg Injection is used in the treatment of the following:

  • Advanced and metastatic breast cancer

  • Metastatic gastric cancer

How the Trastuneal 150mg Injection Works

The protein called HER2 (human epidermal growth factor receptor 2) is found in abundant amounts on the surface of certain cancer cells, where it stimulates cancer growth. Trastuneal 150mg Injection selectively binds to HER2 and stops cancer cell growth.

Interaction of Trastuneal 150mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Trastuneal 150mg Injection and cause undesirable side effects.

Storage Conditions

  • Keep Trastuneal 150mg Injection out of sight and reach of children.

  • Store between 2˚C and 8˚C.

How to Use

Trastuneal 150 mg injection shall be administered either before or after surgery.

It will be given as an Intravenous infusion over 90 minutes; if well tolerated, it shall be administered over 30 minutes for subsequent doses.

Safety Advice

Pregnancy-Unsafe

Pregnancy

Unsafe

Discuss with your physician before taking this Trastuneal 150mg Injection if you are pregnant or think you might be pregnant. Do not take this medicine during pregnancy unless advised by the doctor, as it may cause harm to the unborn baby.

Breast Feeding-Unsafe

Breast Feeding

Unsafe

Avoid breastfeeding your baby while on treatment with Trastuneal 150mg Injection for at least seven months after the final dose.

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

Talk to your doctor if you have any lung conditions before starting treatment with Trastuneal 150mg Injection. 

Liver-Consult Your Doctor

Liver

Consult Your Doctor

You need to tell your physician if you have any liver disorders before starting Trastuneal 150mg Injection, as it requires dosage adjustment for severe liver impairment.

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

Consult your doctor to know if it is safe to consume alcohol while you are on treatment with Trastuneal 150mg Injection.

Driving-Unsafe

Driving

Unsafe

Trastuneal 150mg Injection can cause unusual tiredness and dizziness. Therefore, avoid driving or handling machinery during treatment.

Side Effects

Side effects are unwanted symptoms caused by medicines. Although all medicines can cause side effects, not everyone experiences them.


Serious side effects:

  • Heart Problems

  • Allergic reactions

  • Kidney problems

  • Breathing difficulties


Common side effects:

  • Fever

  • Visual disturbances

  • Nosebleeds or runny nose

  • Hair loss

  • Dizziness

  • Nail disorders

  • Weight loss

  • Loss of appetite

  • Bruising

  • Dry mouth

  • Liver  inflammation

  • Muscle pain

  • Asthma/ lung disorders

Expert Tips

It is suggested to inform your doctor if you have a history of allergic reactions to Trastuneal 150mg Injection to avoid life-threatening complications. If you have a history of lung disorders or breathing problems, inform your doctor before treatment begins. Avoid planning for pregnancy and breastfeeding for a minimum of 7 months after the last dose. Monitor your heart parameters regularly during treatment with Trastuneal 150mg Injection, as it may affect heart function.

FAQs

Q1.

Is Trastuneal 150mg Injection used as a monotherapy in treating breast cancer?

Trastuneal 150mg Injection is generally given along with chemotherapy medication such as paclitaxel or docetaxel, or platinum compounds. Sometimes, it is also given with hormonal agents for those patients with elevated hormonal status.

Q2.

Does Trastuneal 150mg Injection cause heart problems?

Yes, Trastuneal 150mg Injection can damage the heart muscle. To prevent worsening symptoms, it is advised to have a heart checkup every 3 months and continue until 2-5 years after treatment completion.

Q3.

Can I breastfeed while on treatment with Trastuneal 150mg Injection?

No, since it tends to pass into breast milk, it is unsafe to breastfeed. Hence, it is advised not to breastfeed for a minimum of 7 months after treatment with Trastuneal 150mg Injection.

Q4.

Can Trastuneal 150mg Injection be consumed during pregnancy?

No, it is unsafe to consume Trastuneal 150mg Injection while you are pregnant, as this medicine can cause harm to the baby by reducing the amount of amniotic fluid, the fluid surrounding the womb. It can also cause organ developmental issues, such as poor lung development, when consumed during pregnancy. If you are planning for pregnancy, it is advised to discuss birth control methods, as this medicine may impair your fertility.

Fact Box

Molecule name: Trastuzumab

Therapeutic class: Anti-cancer

Pharmacological class: HER2 inhibitor

Indications: 

1. Advanced and metastatic breast cancer

2. Metastatic gastric cancer

References

1. https://www.medicines.org.uk/emc/files/pil.3856.pdf

2. https://www.gene.com/download/pdf/herceptin_prescribing.pdf

3. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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