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  ÂUnigrilin 75mg Injection
Prescription Required
Salt Composition : Eptifibatide
Manufacturer : UNITED BIOTECH PVT LTD
Origin of Medicine : India
1 Vial(s) Of 100ml
Introduction to Unigrilin 75mg Injection
Unigrilin 75mg injection contains active components such as Eptifibatide. This medication is a medication used in the treatment of cardiovascular conditions. It belongs to a class of drugs known as glycoprotein IIb/IIIa inhibitors. It is primarily used in the management of acute coronary syndromes, including unstable angina and non-ST-segment elevation myocardial infarction (NSTEMI). It helps prevent platelet aggregation and blood clot formation within coronary arteries, thereby reducing the risk of further heart-related complications. This medication maintains blood flow within coronary arteries, reducing the chances of new clot formation or worsening of existing clots.
If you have a known hypersensitivity or allergic reaction to this medication, inform your healthcare provider before starting it. Patients with severe kidney disease should not take Unigrilin 75mg injection, as this medication is primarily cleared from the body through the kidneys. People with a history of intracranial bleeding, aortic dissection, or other conditions that could be worsened by anticoagulant therapy may need alternative treatment options. Individuals with a history of bleeding disorders, recent surgery, trauma, or other conditions that increase the risk of bleeding may require careful consideration before using this medication.Â
Uses of Unigrilin 75mg Injection
Unigrilin 75mg injection is used in the following:
- Coronary angioplasty and stent placement
- Acute coronary syndrome (ACS)
Therapeutic Effects of Unigrilin 75mg Injection
Unigrilin 75mg injection acts by binding to platelet glycoprotein IIb/IIIa receptors, obstructing the attachment of fibrinogen and von Willebrand factor. This interference prevents platelet cross-linking, slowing the formation of stable blood clots. This mechanism is essential in situations such as acute coronary syndrome and coronary procedures where controlling clot formation is critical.
Interaction of Unigrilin 75mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Unigrilin 75mg injection, reducing effectiveness by causing undesirable side effects.Â
More Information about Unigrilin 75mg Injection
- Stored at the room temperature from 20°C to 25°C.
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Unigrilin 75mg Injection
Unigrilin 75mg injection is administered through intravenous (IV) infusion, by healthcare provider. During the infusion, the patient's vital signs and overall response to the medication require close monitoring by the health care professional.
Safety Advices for Unigrilin 75mg Injection
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Pregnancy
 ÂUnigrilin 75mg injection's safety during pregnancy has not been well studied. If you are pregnant or planning to become pregnant, consult your doctor before using this medication.
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Breast Feeding
 ÂUnigrilin 75mg injection's compatibility with breastfeeding is not well established. Consult a doctor if you are a breast feeding women before taking this medication.
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Lungs
 ÂUnigrilin 75mg injection should be used cautiously in individuals with severe lung disease. If you have any lung conditions, consult a doctor before starting treatment.
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Liver
 ÂIf you have a history of liver conditions, it's important to consult your doctor before receiving Unigrilin 75mg injection.Â
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Alcohol
 ÂExcessive alcohol consumption can increase the risk of bleeding. It is advisable to avoid excessive alcohol intake while receiving Unigrilin 75mg injection, as alcohol can interact with the medication's effects on blood clotting.
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Driving
 ÂUnigrilin 75mg injection itself is not likely to directly affect your ability to drive. However, if you experience side effects like dizziness, weakness, or other symptoms, use caution and consult your doctor.
Side Effects of Unigrilin 75mg Injection
Unigrilin 75mg injection causes some side effects like all medications, although not everyone will experience them.Â
Serious
- Bleeding
- Thrombocytopenia
- Allergic Reactions
- Thrombosis
Common
- Bleeding at injection site
- Nausea
- Fever
- Headache
- Low blood pressure
Word of Advice
You should tell your healthcare provider if you have had bleeding problems, kidney or liver issues, or allergic reactions to medications before. If you are planning surgery, tell your provider about this medication. Be cautious about medications you take, and don't drink too much alcohol while on this medication. Watch for signs of bleeding, like unusual bruising or blood in urine. Inform emergency responders that you are on this medication. Follow the prescribed dosage closely, and keep emergency contact details handy. If you are pregnant, breastfeeding, or taking other medicines, ask your provider for advice.
FAQs
Q 1. What happens if I miss a dose of Unigrilin 75mg injection?
Unigrilin 75mg injection is administered by healthcare professionals during specific medical procedures. If you're concerned about missing a dose, discuss it with your healthcare provider.
Q 2. Can I eat normally while on Unigrilin 75mg injection?
There are generally no specific dietary restrictions while on Unigrilin 75mg injection. However, it's always a good idea to follow a balanced diet and discuss any dietary changes with your healthcare provider.
Q 3. Is Unigrilin 75mg injection reversible?
Unigrilin 75mg injection's effects on platelets are reversible once the medication is stopped. However, the time it takes for platelet function to return to normal can vary.
Q 4. How often will I be monitored while on Unigrilin 75mg injection?
Healthcare providers will closely monitor you while on Unigrilin 75mg injection, especially during procedures and after administration. Regular blood tests and vital sign checks are common.
Q 5. Can I receive dental procedures while on Unigrilin 75mg injection?
Dental procedures can increase bleeding risk. Inform your dentist about Unigrilin 75mg injection use to determine the best approach and timing for dental work.
Q 6. What should I do if I experience side effects during Unigrilin 75mg injection treatment?
If you experience side effects, especially severe ones like significant bleeding or allergic reactions, seek immediate medical attention and inform your healthcare provider.
Fact Box of Unigrilin 75mg Injection
Molecule name:Â Â Eptifibatide | Therapeutic class: Antiplatelet Agents |
Pharmacological class: Glycoprotein IIb/IIIa inhibitors. | Indications:  1. Coronary angioplasty and stent placement 2. Acute coronary syndrome (ACS) |
References
- GlaxoSmithKline UK Limited, Electronic medicines compendium (EMC) [Revised on 21 May 2021] [Accessed on 18th Dec 2023], https://www.medicines.org.uk/emc/product/3889/smpc
- Kerstin Hogg and Jeffrey I. Weitz, Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs, Goodman and Gilman’s Pharmacological Basis of Therapeutics, 585-603
- Merck & Co.Inc.US Food and Drug Administration, [Revised on 2nd 2021] [Accessed on 18th August 2023], /https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/020718s039lbl.pdf
Disclaimer
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