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Upadoz 30mg Tablet 10's
Last updated on 26 Sep 2026 | 08:41 AM (IST)
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Introduction
Upadoz 30mg Tablet 10's is a prescription medicine used to manage various autoimmune and inflammatory conditions in adults. It belongs to the class of Janus kinase (JAK) inhibitors and works by reducing the activity of certain enzymes involved in immune system signalling. By targeting abnormal immune activity, Upadacitinib helps relieve symptoms such as inflammation, swelling, stiffness, and pain.
Its oral tablet form makes it more convenient than injectable biologics, offering long-term disease control and improved quality of life. However, regular monitoring of blood counts, liver function, and cholesterol is necessary during treatment, as it may increase the risk of infections such as tuberculosis, herpes zoster, or pneumonia. It is not recommended for use during pregnancy or breastfeeding without medical advice, and patients with a history of heart disease, cancer, blood clots, or chronic infections should inform their doctor before starting therapy.
Uses
Treatment of moderate to severe Rheumatoid Arthritis in adults who did not respond well to other medicines.
Management of Psoriatic Arthritis in adults with an inadequate response to conventional therapies.
Treatment of moderate to severe Atopic Dermatitis in adults who are candidates for systemic therapy.
Treatment of active Ankylosing Spondylitis in adults who did not respond adequately to conventional therapies.
Treatment of moderately to severely active Ulcerative Colitis in adults who have had an inadequate response or intolerance to other medicines.
How Upadoz 30mg Tablet 10's Works
In autoimmune diseases, the body’s immune system becomes overactive and attacks its own tissues, causing inflammation and damage. Upadacitinib inhibits Janus kinase (JAK) enzymes, which transmit signals that activate inflammation. Blocking these signals reduces immune system overactivity, lowers inflammation, and helps control symptoms of chronic inflammatory conditions.
Interaction of Upadoz 30mg Tablet 10's with Other Drugs
Inform your doctor if you are taking any:
Prescription medicines (especially biologics, immunosuppressants, or corticosteroids).
Over-the-counter (OTC) drugs.
Herbal products or vitamin supplements.
Some medicines may increase the risk of infections, liver injury, or other side effects when taken with Upadacitinib. Always share your full medication history with your physician.
Storage Conditions
Store at room temperature (15–30°C).
Keep away from moisture and direct sunlight.
Do not use expired or damaged medication.
Keep out of reach of children
How to Use
Take this medicine exactly as your doctor prescribed.
Usually taken once daily, with or without food.
Swallow the Tablets whole; do not crush or chew.
Your doctor will decide the dose based on your condition and overall health.
Safety Advice
Pregnancy
Upadacitinib may harm the unborn baby. Do not use during pregnancy. Inform your doctor if you are pregnant or planning to conceive.
Breast Feeding
Avoid use while breastfeeding, as it may pass into breast milk and harm the infant.
Lungs
Inform your doctor if you have lung disease or issues before starting treatment.
Liver
Inform your doctor if you have liver disease before starting treatment.
Alcohol
Avoid excessive alcohol consumption, as it may worsen liver-related side effects.
Driving
Some patients may experience dizziness and fatigue. Avoid driving or operating heavy machinery if you experience these effects.
Side Effects
Serious:
Severe infections (tuberculosis, pneumonia, shingles)
Blood clots (in legs or lungs)
Chest pain, shortness of breath
Severe stomach pain or black stools
Allergic reactions (rash, swelling of face/lips, difficulty breathing)
Liver problems (yellowing of eyes/skin, dark urine)
Common:
Nausea
Cough
Fever
Headache
Stomach pain
Tiredness
Upper respiratory tract infections
Acne
Expert Tips
Do not start treatment if you have an active infection.
Your doctor may test for tuberculosis and hepatitis before starting therapy.
Routine blood tests (liver, kidney, cholesterol, blood counts) are required during treatment.
Inform your doctor if you are scheduled for vaccinations, as live vaccines are not recommended while on Upadacitinib.
Always take the medicine as directed; do not stop suddenly without consulting your physician.
FAQs
Q1.
What is Upadoz 30mg Tablet 10's used for?
It is used to treat autoimmune conditions like rheumatoid arthritis, psoriatic arthritis, atopic dermatitis, ankylosing spondylitis, and ulcerative colitis.
Q2.
What is the correct way to use Upadoz 30mg Tablet 10's?
Take once daily as prescribed by your doctor, with or without food. Swallow the Tablet 10's whole.
Q3.
Can I use Upadacitinib with other arthritis medicines?
Do not combine it with other biologic disease-modifying antirheumatic drugs (DMARDs). Inform your doctor about all medicines you are taking.
Q4.
Does Upadacitinib weaken the immune system?
Yes, since it suppresses immune activity, it may increase the risk of infections.
Q5.
Do I need regular check-ups while taking this medicine?
Yes. Regular blood tests are needed to monitor liver function, kidney function, and blood counts.
Fact Box
Molecule name | Upadacitinib |
Therapeutic class | Immunomodulators |
Pharmacological class | Janus kinase (JAK) inhibitors |
Indications | Rheumatoid Arthritis, Psoriatic Arthritis, Atopic Dermatitis, Ankylosing Spondylitis, Ulcerative Colitis |
References
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Naina Boruah
MSc Biomedical Science
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 26 Sep 2026 | 08:41 AM (IST)
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