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Upxiga 100000IU Injection
Prescription Required
Salt Composition : Ulinastatin
Manufacturer : LUPIN LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Upxiga 100000iu Injection
Upxiga 100000IU Injection contains an active component as Ulinastatin. It is also known as a urinary trypsin inhibitor (UTI). It is a medication used in some countries for its anti-inflammatory and immunomodulatory effects. It was initially isolated from human urine and has been studied for potential therapeutic benefits. The primary use is the treatment of acute pancreatitis, a condition characterized by pancreas inflammation. It is believed to work by inhibiting certain enzymes and factors involved in the inflammatory response, thus helping to reduce the severity of the condition. Additionally, Upxiga 100000IU Injection has been investigated for its potential benefits in other conditions, including sepsis (severe bacterial infection), multiple organ failure, and acute respiratory distress syndrome (ARDS). Its ability to modulate the immune response and reduce inflammation makes it a candidate for these conditions where excessive immune reactions can damage tissue.
Upxiga 100000IU Injection may not be suitable for everyone. It is contraindicated in patients with a known hypersensitivity to the drug or its components. Limited research may be available regarding the safety and efficacy of this medication in certain populations, such as pediatric patients or the elderly. Extra caution and expert guidance are needed when using this medication in these groups. Upxiga 100000IU Injection may interfere with certain laboratory tests, potentially affecting the accuracy of results. Inform your healthcare provider about using this medication if you undergo diagnostic tests. Abruptly stopping treatment, especially in critically ill patients, may have adverse effects.
Uses of Upxiga 100000iu Injection
Upxiga 100000IU Injection is used to treat the following:
- Acute pancreatitis
- Sepsis
- Acute respiratory distress syndrome
Therapeutic Effects of Upxiga 100000iu Injection
Upxiga 100000IU Injection's mechanism of action involves inhibiting various proteolytic enzymes, such as trypsin and elastase, which are crucial in promoting inflammation and tissue damage. By suppressing these enzymes, this medication reduces the activation of inflammatory pathways and modulates the immune response, ultimately leading to decreased inflammation and potential mitigation of tissue injury.
Interaction of Upxiga 100000iu Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Upxiga 100000IU Injection, reducing effectiveness by causing undesirable side effects.
More Information about Upxiga 100000iu Injection
- Store at temperature 2°C - 8°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Upxiga 100000iu Injection
Upxiga 100000IU Injection is administered intravenously (vein injection) under medical supervision. Your healthcare professional will determine the specific dosage and administration guidelines based on your condition and needs.
Safety Advices for Upxiga 100000iu Injection
Pregnancy
If you are pregnant or planning to become pregnant and require treatment with Upxiga 100000IU Injection, it is crucial to consult your healthcare provider.
Breast Feeding
If you are breastfeeding or planning to breastfeed and require treatment with Upxiga 100000IU Injection, it is crucial to discuss the matter thoroughly with your healthcare provider.
Lungs
If you have a lung condition or are considering Upxiga 100000IU Injection treatment for any respiratory issue, it is vital to consult with a qualified healthcare professional. They can assess your medical history, perform a thorough evaluation, and determine the most appropriate treatment plan.
Liver
If you have a liver condition or concerns about Upxiga 100000IU Injection's safety in your liver health, it is crucial to discuss this with your healthcare provider.
Alcohol
Both alcohol and Upxiga 100000IU Injection can impact the central nervous system, and combining the two may cause increased drowsiness or impair cognitive function.
Driving
Upxiga 100000IU Injection can cause certain side effects that may impair your ability to drive safely. These side effects can include dizziness, lightheadedness, blurred vision, and transient changes in heart rhythm. These effects can interfere with your concentration, alertness, and coordination, making driving potentially unsafe.
Side Effects of Upxiga 100000iu Injection
Upxiga 100000IU Injection causes some side effects like all medications, although not everyone will experience them.
Serious:
- Severe allergic reactions (difficulty breathing, swelling of the face or throat, hives, itching)
- Anaphylaxis (a life-threatening allergic reaction)
- Signs of an infection (fever, persistent sore throat)
- Changes in kidney function (changes in urine output, swelling of the legs or ankles)
- Abnormal bleeding or bruising
- Liver problems (yellowing of the skin or eyes, dark urine, abdominal pain)
- Neurological symptoms (confusion, seizures, difficulty speaking or moving)
Common:
- Nausea
- Vomiting
- Diarrhea
- Skin rashes or itching
- Headache
- Dizziness
- Fever or chills
- Injection site reactions (pain, redness, or swelling)
Word of Advice
Patients with known hypersensitivity to Upxiga 100000IU Injection or any of its components should not use the medication. Regular monitoring of kidney and liver function is essential, and dose adjustments may be necessary for patients with impaired organ function. Caution is advised in pregnant and breastfeeding individuals, and the medication should only be used if needed and under medical supervision. Close monitoring for signs of allergic reactions, infections, and changes in blood counts is recommended. Patients with a history of gastrointestinal or bleeding disorders should be closely monitored during treatment. It's important to discuss all medical conditions and medications with the healthcare provider to ensure the safe and effective use of these medications.
FAQs
Q 1. What are the common side effects of Upxiga 100000IU Injection?
Common side effects of Upxiga 100000IU Injection may include nausea, vomiting, diarrhea, skin rashes, headache, and injection site reactions. These side effects are usually mild and may subside with continued treatment.
Q 2. Can Upxiga 100000IU Injection be used in children?
The safety and efficacy of Upxiga 100000IU Injection in pediatric populations, especially infants, are not fully established. Special care should be taken when using in children.
Q 3. How long is the duration of Upxiga 100000IU Injection treatment?
The duration of Upxiga 100000IU Injection treatment varies depending on the specific medical condition being treated, the patient's response to therapy, and the healthcare provider's assessment. In some cases, this medication may be given for a short course, while in others, it may be required for a more extended period.
Q 4. Can I stop taking Upxiga 100000IU Injection if my symptoms improve?
It is essential to complete the full course of Upxiga 100000IU Injection treatment as prescribed by your healthcare provider, even if your symptoms improve. Stopping the medication prematurely may lead to a recurrence of the condition or incomplete recovery.
Q 5. How quickly does Upxiga 100000IU Injection start working?
The onset of Upxiga 100000IU Injection's action may vary depending on the individual and the specific medical condition being treated. It is best to consult your healthcare provider about the expected time frame for the medication's effects in your particular case.
Q 6. Does Upxiga 100000IU Injection require any special monitoring?
Patients receiving Upxiga 100000IU Injection may require regular monitoring of kidney and liver function, blood cell counts, and overall clinical status. This helps ensure the medication's safety and efficacy and allows for timely adjustments.
Q 7. What should I do if I miss a dose of Upxiga 100000IU Injection?
If you miss a scheduled dose of Upxiga 100000IU Injection, contact your healthcare provider for guidance. They will advise you on the appropriate course of action.
Fact Box of Upxiga 100000iu Injection
Molecule name: Ulinastatin | Therapeutic class: Urinary Trypsin Inhibitor |
Pharmacological class: Protease Inhibitors
| Indications: 1. Acute pancreatitis 2. Sepsis 3. Acute respiratory distress syndrome |
References
- Bharat Serums and Vaccines Limited, [Accessed on 27th July 2023], https://www.bharatserums.com/assets/pdf/products/Upxiga(Liquid).pdf
- Qiancheng Xu et al; Ulinastatin is effective in reducing mortality for critically ill patients with sepsis: a causal mediation analysis; Scientific Reports; [Published on 25/09/2018]; [Accessed on 27/07/2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc6156583/
- Ling-Zhang wang et al; Effect of Ulinastatin on serum inflammatory factors in Asian patients with acute pancreatitis before and after treatment: a meta-analysis; International Journal of Clinical Pharmacology and Therapeutics; [Published on Nov 2016]; [Accessed on 27/07/2023]; https://pubmed.ncbi.nlm.nih.gov/27569736/
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