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Valgan 450mg Tablet
Last updated on 21 Aug 2026 | 05:19 AM (IST)
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Valgan 450mg Tablet is a prescription medicine used to treat and prevent cytomegalovirus (CMV) infections, particularly in patients with weakened immune systems or those who have undergone organ transplantation. It contains valganciclovir, an antiviral agent that works by inhibiting the replication of the virus, helping to control the infection. Valgan 450mg Tablet should be taken under strict medical supervision as part of a comprehensive antiviral treatment plan.
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Introduction
Valgan 450mg tablet is an antiviral medication with an active ingredient called Valganciclovir. It belongs to the group of Antiviral (Non-HIV) drugs. Once inside the body, Valganciclovir is converted into Ganciclovir, which helps fight viral infections effectively.
This medicine is mainly prescribed to treat Cytomegalovirus (CMV) infections of the retina of the eye in adults with Acquired Immune Deficiency Syndrome (AIDS), a condition that can lead to vision problems and even blindness. It is also used to prevent CMV infections in adults and children who have received an organ transplant from a donor infected with CMV.
Patients often search for details like Valgan 450mg tablet price and availability. It is manufactured by Cipla, hence commonly referred to as Valgan 450mg tablet Cipla. Doctors carefully decide the Valgan tablet dosage 450mg based on the patientās health condition and medical history. If this tablet is not suitable, your physician may recommend Valgan tablet substitutes.
When discussing treatment options, comparisons such as Valgan vs Valganciclovir are also common, since both medicines are related. Your doctor will guide you on how to take Valgan 450mg tablet safely and effectively. Like any medication, it may cause some side effects, so itās important to be aware of possible Valgan tablet side effects and report any unusual symptoms to your healthcare provider.
Uses
valgan 450mg uses areĀ
- Treatment and prevention of Cytomegalovirus (CMV) infection
How Valgan 450mg Tablet works
Valgan 450mg tablet is an antiviral medication. After administration, liver enzymes rapidly convert the Valgan 450mg tablet into Ganciclovir. Ganciclovir prevents virus growth by inhibiting viral DNA synthesis.
Interaction of Valgan 450mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Valgan 450mg tabletĀ and can cause undesirable side effects.Ā
Storage conditions
- Keep out of sight and reach of pets and children
- Store at room temperature between 15°C to 30°C.
- Do not freeze.
How to take Valgan 450mg Tablet
Take the Valgan 450mg tablet as advised by your physician. Swallow the tablets whole and intact. This tablet should be taken with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.
Safety Advice for Valgan 450mg Tablet
Breast Feeding
Taking Valgan 450mg tablet while breastfeeding may be unsafe because it may affect the child. Talk to your physician to get more information.Ā
Alcohol
It is unknown whether consuming alcohol while taking a Valgan 450mg tablet is safe. Please speak with your physician.
Liver
It is unknown whether Valgan 450mg tablet is safe to administer in patients with liver problems. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
Lungs
It is unknown whether Valgan 450mg tabletĀ is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
While taking Valgan 450mg tablet , it is unsafe to drive or use machines because it may cause dizziness, shaky, changes in vision, etc. Talk to your doctor for more information.Ā
Pregnancy
Taking Valgan 450mg tablet while pregnant can harm the baby. You should not take this medicine during the pregnancy unless your doctor recommends taking it. Inform your doctor if you are pregnant or planning to get pregnant before taking this medicine. Use effective contraception to avoid pregnancy.
Side Effects
Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.Valgan 450mg side effects areĀ
Serious
- Anaphylactic shock (sudden swelling of the throat, face, lips, hand, ankles, difficulty swallowing, itchy skin rash)
- Low blood counts (shortness of breath, pale skin, mouth ulcers, sore throat)
- Blood infection
- Severe stomach pain which spreads into your back
- Seizures
Common
- Respiratory tract infections
- Loss of appetite
- Headache, Dizziness
- Cough, fever
- Diarrhea, constipation
- Tiredness, feeling sick
- Infections in the urinary tract, skin
- Weight loss
- Anxious, confused, depression
- Troubled sleeping
- Abnormal sensation of skin (tickling, pricking, burning, tingling)
- Changes in taste
- Eye, ear pain
- Night sweats
- Joint pain, muscle spasms
- Hair loss
- Low blood pressure
Expert Tips
-
Discuss effective contraception methods with your doctor, along with any fertility concerns.
-
Do not stop taking the medicine unless advised by your doctor.
-
Notify your doctor immediately if you experience any serious side effects.
-
Inform your physician if you have liver problems, as Valgan 450mg Tablet should be used cautiously in such cases.
-
Your doctor may adjust your dosage based on your kidney function.
FAQs about Valgan 450mg Tablet
Q1.
Should I use contraception during and after the treatment of the Valgan 450mg tablet?
Yes, it is advised to use contraception during and after the treatment to avoid unwanted pregnancy. Both women and men are advised to use contraception. After the treatment, it is suggested to use condoms for 30 days in women and 90 days in men
Q2.
What are the best ways to deal with side effects of Valgan 450mg Tablet?Ā
Contact the healthcare professional instantly if you experience any side effects while taking the Valgan 450mg tablet. They may prescribe some over-the-counter or prescription medications to manage the side effects or reduce the tablet dosage.Ā
Q3.
What is the treatment duration for Valgan 450mg Tablet?
The period of the treatment completely depends on the specific condition being treated and the individual patient. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the Valgan 450mg tablet if your doctor advises you to stop.
Q4.
Can patients with impaired kidney function use Valgan 450mg tablet?Ā
Valgan 450mg tablet should be used cautiously in individuals with impaired kidney function. Dose adjustments may be necessary, and close monitoring of kidney function is important.
Q5.
Is it safe to drink alcohol while taking Valgan 450mg tablet?
It is unknown whether consuming alcohol while taking Valgan 450mg tablet is safe. Drinking alcohol while consuming the medicine is generally not recommended as alcohol may increase the risk of certain side effects, such as dizziness or drowsiness, associated with the medicine. Talk with your doctor for more information.Ā
Fact Box of Valgan 450mg Tablet
| Molecule Name | ValganciclovirĀ |
| Therapeutic class | Anti-infectionĀ |
| Pharmacological class | Antiviral (Non-HIV) drugs |
| Indications | Treatment and prevention of Cytomegalovirus (CMV) infectionĀ |
References
- KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 801.
- Roche Products Limited, Electronic medicines compendium (EMC), [ Revised on April 2022] [ Accessed on 11th May 2023], pil.13566.pdf (medicines.org.uk)
- Genentech USA, US Food and Drug Administration, [ Revised on Aug 2010] [ Accessed on 11th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021304s008,022257s003lbl.pdf
Disclaimer
MrMedās primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Aswini Priya Velmurugan
PG in Biotechnology

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 21 Aug 2026 | 05:19 AM (IST)

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