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Quick Summary

Vonavir Tablet

efavirenz,emtricitabine,tenofovir disoproxil fumarate

Written By:Dr. Deva Prasath S.Pharm D Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 31 Mar 2026 | 09:31 AM (IST)

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EFAVIRENZ,EMTRICITABINE,TENOFOVIR DISOPROXIL FUMARATE

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30 Tablet(...

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EFAVIRENZ,EMTRICITABINE,TENOFOVIR DISOPROXIL FUMARATE

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Teevir Tablet

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Virashiv Tablet

SHIVNAAM TRADEL...

₹ 39.07/tablet

28% cheaper

Virarazer Tablet

APRAZER HEALTHC...

₹ 39.70/tablet

27% cheaper

Trustiva Tablet

HETERO HEALTHCA...

₹ 44.20/tablet

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Introduction to Vonavir Tablet

Vonavir Tablets contain two active substances, Emtricitabine and Tenofovir disoproxil fumarate. These medications are a part of the standard combination therapy for HIV, known as antiretroviral therapy (ART). It is a combination drug regimen that is commonly used for the effective treatment of HIV-1 infection. When used correctly and consistently, Vonavir tablets have demonstrated high efficacy in HIV treatment and prevention.

Antiviral medications help postpone the effects of AIDS and enhance the overall quality of life. For individuals with high viral loads, this combo therapy is ideal. Although this medication greatly lowers the risk of viral infection, it does not treat HIV, and there are still chances that HIV will spread to other individuals. It is given to adults and kids over the age of 12 with a body weight of more than 35 kg.

These should not be used in individuals with known hypersensitivity or severe allergic reactions to Emtricitabine, Tenofovir disoproxil fumarate, or any medication components. This medication is not recommended in individuals with severe renal impairment or end-stage renal disease who are not receiving hemodialysis.

Uses of Vonavir Tablet

Vonavir Tablet is used to treat HIV-1 infection.

Therapeutic Effects of Vonavir Tablet

Vonavir Tablet has therapeutic effects in treating HIV infection and pre-exposure prophylaxis (PrEP). They work by inhibiting HIV replication, reducing viral load, improving immune function, and slowing the progression of HIV disease. In individuals with HIV, these medications help control the virus, maintain a low viral load, and improve overall health outcomes.

Interaction of Vonavir Tablet with other drugs

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Vonavir Tablet, reducing effectiveness by causing undesirable side effects.

More Information about Vonavir Tablet

Store at a temperature between 20°C to 25°C (68°F to 77°F).
Keep away from moisture, heat, and light.
It should not be frozen.
Keep it in its original packaging.
Keep away from children and pets.

How to consume Vonavir Tablet

To properly consume Vonavir Tablet, follow your healthcare provider's instructions regarding dosage, frequency, and duration. Take it with or without food, swallowing the tablets or capsules with water. Adhere to the prescribed dosing schedule; do not alter the dosage without consulting your healthcare provider.

Safety Advice for Vonavir Tablet

Breast Feeding

Consult Your Doctor

Vonavir Tablet is excreted into human breast milk, but the potential risks to the infant are not well established. So patients should consult a doctor before taking it.

Alcohol

Unsafe

It is generally recommended to avoid excessive alcohol consumption while taking Vonavir Tablet or any medication. Alcohol can interact with this medication and affect liver function.

Liver

Consult Your Doctor

The safety of Vonavir Tablet in individuals with liver disease may depend on the specific type and severity of liver disease and other factors. It is important to consult with a healthcare provider.

Lungs

Consult Your Doctor

Suppose you have a history of lung disease or are experiencing respiratory symptoms while taking it. Then it is important to consult the healthcare provider for a thorough evaluation before taking Vonavir Tablet.

Driving

Unsafe

Some people experience side effects, including dizziness, drowsiness, or fatigue, while taking Vonavir Tablet. Suppose anyone experiences any of these side effects or any other symptoms that may interfere with your ability to drive safely. In that case, avoid driving or operating heavy machinery.

Pregnancy

Consult Your Doctor

If you are pregnant or plan to become pregnant, it is crucial to consult with your healthcare provider before taking Vonavir Tablet.

Side Effects of Vonavir Tablet

Vonavir Tablets cause side effects like all medications, although not everyone will experience them.

Serious:

Kidney problems or renal toxicity
Decreased bone mineral density or bone loss
Lactic acidosis (a huge accumulation of lactic acid in the blood)
Hepatic steatosis (fat accumulation in the liver)
Immune reconstitution syndrome (a paradoxical worsening of pre-existing infections or inflammatory conditions when the immune system strengthens)

Common:

Nausea
Diarrhea
Headache
Fatigue
Dizziness
Insomnia
Rash

Word of Advice

If you are considering taking Vonavir Tablet, knowing the potential risks and warnings associated with this medication is important. Pregnancy and breastfeeding require individual evaluation and consultation with a doctor to weigh the benefits against potential risks. It should be used cautiously in individuals with pre-existing conditions such as liver disease, kidney disease, or bone disorders, as it may exacerbate them. Close monitoring and appropriate management are necessary in these cases. Adherence to these precautions and regular monitoring and communication with the healthcare provider can help ensure safe and effective use.

FAQs about Vonavir Tablet

Q1.

Can Vonavir Tablet be taken with other antiretroviral medications?

Vonavir Tablet is often combined with other antiretroviral medications as part of a multidrug regimen for treating HIV infection. The specific combination of medications will depend on individual health status, treatment history, and potential drug interactions.

Q2.

Can Vonavir Tablet be safely used by older adults?

Vonavir Tablet can be used in older adults. Still, dosage adjustments or additional monitoring may be necessary, as age-related changes in kidney and liver function can affect medication clearance. It is important to discuss individual health status and any concerns with a healthcare provider.

Q3.

Can Vonavir Tablet be used in individuals with pre-existing bone conditions?

Individuals with pre-existing bone conditions, such as osteoporosis or osteopenia, may require careful monitoring and management when using Vonavir Tablet. It is important to discuss any underlying bone conditions with your healthcare provider to ensure appropriate bone health monitoring and potential supplementation.

Q4.

Can Vonavir Tablet prevent all forms of HIV transmission?

Vonavir Tablet, when used as PrEP, significantly reduces the risk of HIV transmission through sexual activity or injection drug use. However, they do not provide 100% protection against HIV, and it is important to continue practicing safe sex and taking other preventive measures.

Q5.

Can Vonavir Tablet cause lactic acidosis?

Although rare, Vonavir Tablet has been associated with the risk of lactic acidosis. Lactic acidosis is a serious condition characterized by the accumulation of lactic acid in the blood. It is important to promptly report any symptoms such as unusual weakness, rapid breathing, nausea, vomiting, abdominal pain, or unexplained muscle pain to your healthcare provider while taking it.

Q6.

Are any specific tests or monitoring required for bone health while taking Vonavir Tablet?

Monitoring of bone mineral density may be recommended for individuals on long-term treatment with Tenofovir disoproxil fumarate. Your healthcare provider may request bone density scans or blood tests to assess bone health and determine if any interventions or additional treatments are necessary.

Q7.

Can Vonavir Tablet be used in individuals with liver or kidney disease?

Vonavir Tablets should be used cautiously in individuals with liver or kidney impairment. Dose adjustments or alternative treatment options may be necessary.

Fact Box of Vonavir Tablet

Molecule name: Emtricitabine and Tenofovir disoproxil fumarate	Therapeutic class: Antiretroviral agents
Pharmacological class: Nucleoside reverse transcriptase inhibitors (NRTIs)	Indications: HIV- 1 Infection

References

KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
Gilead Sciences, Inc, US Food and Drug Administration, [ Revised on March 2016] [ Accessed on 19th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021752s047lbl.pdf

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