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Zemasin 25mg Tablet
Last updated on 09 May 2026 | 07:19 AM (IST)
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Introduction to Zemasin 25mg Tablet
Zemasin 25mg tablet is an anticancer drug with the active ingredient Exemestane. It belongs to the medication class known as aromatase inhibitors. In postmenopausal women, it is used to treat hormone-dependent early breast cancer after completing 2-3 years of treatment with Tamoxifen. In addition, it also treats hormone-dependent advanced breast cancer. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner. Do not take this medicine if you are allergic to Exemestane or any of the other ingredients of this medicine and if you have not been through the menopause stage, also if you think you are pregnant or breastfeeding.
Zemasin 25mg tablet is not recommended for adolescents and children under the age of 18. Inform your doctor before starting the treatment, if you have problems with your liver or kidney or if you have a history of the bone condition as this medicine can make you lose mineral content and decrease its strength. Inform your doctor if you take any other medicine while under this treatment. Regular checking will be conducted to monitor the vitamin D level, if your level is below normal you will be given vitamin D. You need to tell your doctor about all the medications you are taking recently before taking this medicine. Use effective birth control during the treatment with this medicine.
Uses of Zemasin 25mg Tablet
- Breast cancer
Therapeutic Effects of Zemasin 25mg Tablet
Zemasin 25mg inhibits the enzyme aromatase, which is responsible for the conversion of androgens (male hormones) to estrogen (female hormones). By inhibiting aromatase, Zemasin 25mg reduces the levels of estrogen in the body. This can stop or reduce the growth of different hormone-sensitive breast cancer cells, which depends on estrogen.
Interaction of Zemasin 25mg Tablet with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications may interact such as Rifampicin, Carbamazepine, or phenytoin, and St. John Wort interacts with Zemasin 25mg and reduces effectiveness by causing undesirable side effects.
More Information about Zemasin 25mg Tablet
- Keep the tablets away from light and moisture.
- Keep the tablets out of the reach of children and animals.
- This medicine does not require any special storage conditions.
How to consume Zemasin 25mg Tablet
Swallow the tablet whole with water. The usual recommended dose is one tablet daily. Avoid chewing, breaking, or crushing it. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advice for Zemasin 25mg Tablet
Breast Feeding
It is unsafe to breastfeed while taking Zemasin 25mg because it can cause toxicity to the baby. Please consult your physician for more advice.
Alcohol
It is unknown if drinking alcohol while taking a Zemasin 25mg tablet is safe. Please speak with your physician.
Liver
Inform your physician about any underlying liver disorders before taking Zemasin 25mg, as this medication should be used with caution in liver disease patients.
Lungs
It is unknown if patients with lung conditions can consume Zemasin 25mg. So, before beginning the treatment, consult your doctor if you have any lung conditions.
Driving
Zemasin 25mg may affect the ability to drive in some patients. Hence, it is advised to avoid driving if you feel tired or weak while taking this injection.
Pregnancy
Do not take this Zemasin 25mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment.
Side Effects of Zemasin 25mg Tablet
Side effects are unwanted symptoms produced by medication. Even though all medications cause side effects, not everyone gets them.
Serious
- Lowered white blood cell (leukopenia)
- Reduction of platelets in the blood
- Allergic reaction
- Difficulty in breathing
Common
- Numbness and hand pain (Carpal tunnel syndrome)
- Depression
- High levels of liver enzymes
- Diarrhea, Nausea
- Depression
- Joint and back pain
- Fatigue
- Abdomen pain
- Swelling in hands and feets
- Muscle pain
- Tingling, pain, coldness, weakness in parts of the hand.
Word of Advice
It is advised to inform your doctor if you have a history of liver or kidney diseases. Zemasin 25mg reduces levels of the estrogen hormone. You can have weaker bones that are more likely to break. Do not get pregnant or breastfeed. Use effective contraception throughout the treatment.
FAQs about Zemasin 25mg Tablet
Q1.
Can Zemasin 25mg cause bone disease?
Zemasin 25mg can weaken your bones and increase your risk of fractures (a condition called osteoporosis). Your provider might ask you to do a bone mineral density (BMD) test while taking this medicine to ensure that your bones are healthy and strong.
Q2.
Will it affect my contraception or fertility?
Zemasin 25mg is generally given to you only if you have gone through menopause. However, some people find that they start to have periods again after taking Exemestane. If this happens to you, it’s important to use reliable contraception. Talk to your doctor if your periods start again or if there is any chance that you maybe are pregnant it is not recommended during pregnancy.
Q3.
Can Zemasin 25mg be used in men?
Zemasin 25mg is not approved for use in men, as it is specifically designed to treat hormone receptor-positive breast cancer in postmenopausal women.
Q4.
Are there any drug interactions with Zemasin 25mg?
Yes, Zemasin 25mg may interact with certain medications, including tamoxifen, estrogen-containing products, and certain antibiotics. inform your healthcare provider of all medications you are taking, including over-the-counter medications and supplements, before starting treatment with this medicine.
Q5.
Can Zemasin 25mg cause any kidney-related problems?
Care has to be given if you have any kidney-based problems. Inform your doctor if you have any history of kidney problems
Fact Box of Zemasin 25mg Tablet
Molecule name: Exemestane | Therapeutic class: Anti-Cancer |
Pharmacological class: Aromatase Inhibitor | Indication: Hormone-dependent breast cancer. |
References
- Zentiva Pharma UK limited, Electronic medicines compendium (EMC), [Revised on July 2022] [Accessed on 21st April 2023], Exemestane 25mg film-coated tablets - Patient Information Leaflet (PIL) - (emc) (medicines.org.uk)
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
Disclaimer
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Author Details
Written By
Aswini Priya Velmurugan
PG in Biotechnology
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 09 May 2026 | 07:19 AM (IST)
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