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Zeroklot NXT 300mg Injection

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enoxaparin

1435

MRP: 3588

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1 CARTRIDGE(s) OF 3ML

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Zeroklot NXT 300mg Injection
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1435

MRP: 3,588.00

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1 Cartridg...

1 Cartridge(s) Of 3ml

1435.0/Unit
Prescription Required
Prescription Required

Salt Composition

ENOXAPARIN

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SAMARTH LIFE SCIENCES PVT LTD

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Introduction

Zeroklot NXT 300mg Cartridge Injection is an anticoagulant belonging to the low-molecular-weight heparin (LMWH) class, containing Enoxaparin as its active ingredient. Zeroklot Injection uses include treatment of severe blood clots, and Zeroklot NXT for DVT treatment is one of its key applications, preventing deep vein thrombosis in patients undergoing abdominal surgery, hip replacement surgery, or knee replacement surgery, as well as those with severe movement restrictions. As a zeroklot NXT anticoagulant injection, it also prevents further heart complications in patients with unstable angina and non-Q-wave myocardial infarction. Zeroklot NXT Injection side effects and risks are higher in patients with active bleeding, hypersensitivity or allergies to the active compound, or a history of heparin-induced thrombocytopenia; hence, Zeroklot inj is not recommended in such cases.

Before taking zeroklot, tell your physician if you are allergic to Enoxaparin, heparin, benzyl alcohol, or pork products. Your healthcare provider will regularly monitor you for signs of bleeding, and patients with kidney problems should inform their healthcare practitioner before starting treatment. It is not recommended for use in children and adolescents below 18 years.

Zeroklot NXT 300mg Cartridge Injection is not recommended if you undergo procedures like neuraxial anaesthesia or spinal puncture, and older adults and patients with low weight should be monitored for increased risk of bleeding. Tell your physician if you suspect pregnancy, are breastfeeding, or are planning to have a baby, as it may increase the chance of bleeding in pregnant women with artificial heart valves. Inform your physician about all drugs you are taking, including herbal and vitamin supplements, and avoid hemostatic drugs unless absolutely necessary. The zeroklot injection price varies by retailer and location; check the current price and buy Zeroklot NXT 300mg Cartridge Injection online at MrMed with pan-India delivery.

Uses

Zeroklot NXT 300mg Injection 60mg is used for the treatment of the following:

  • Deep vein thrombosis

  • Prophylaxis of venous thromboembolism

  • Unstable angina 

  • ST-segment Elevation Myocardial Infarction (STEMI)

  • Prevention of blood clots during surgeries.

How Zeroklot NXT 300mg Injection Works

Zeroklot NXT 300mg Injection binds to the antithrombin to form a complex. Antithrombin is a protein that blocks the formation of abnormal blood clots. This drug primarily inhibits the activation of factor Xa, thereby preventing clot formation. It is commonly used for the prevention and treatment of conditions associated with increased risk of blood clots. 

Interaction of Zeroklot NXT 300mg Injection with other drugs:

  1. Anticoagulants (Severe)
    Using medicines like warfarin, dabigatran, or rivaroxaban with enoxaparin can strongly increase bleeding risk. This combination needs strict medical supervision and frequent clotting checks.

  2. Antiplatelet Agents (Severe)
    Drugs such as aspirin, clopidogrel, or ticagrelor may significantly raise the chance of bleeding when taken with enoxaparin. Doctors usually avoid or closely monitor this combination.

  3. NSAIDs (Severe)
    Pain relievers like ibuprofen and diclofenac can irritate the stomach and increase bleeding risk with enoxaparin. Use them only if your doctor approves.

  4. Thrombolytics (Severe)
    Medicines such as alteplase or streptokinase can significantly increase bleeding when co-administered with enoxaparin. They should be used together only in controlled clinical settings.

  5. SSRIs and SNRIs (Moderate)
    Antidepressants such as sertraline or venlafaxine may enhance bleeding tendency. Monitoring is recommended, especially in long term use.

  6. Herbal Supplements (Moderate)
    Ginkgo, garlic, ginger, or high dose vitamin E can increase bleeding risk when taken with enoxaparin. Inform your doctor about any herbal products you use.

Storage Conditions

  • Store Zeroklot NXT 300mg Injection below 25 °C.

  • Do not freeze

  • Keep it out of reach from children.

  • Protect them from light and moisture.

How to use Zeroklot NXT 300mg Injection

Zeroklot NXT 300mg Injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered as an intravenous injection into a vein. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Safety advice

Pregnancy-Consult Your Doctor

Pregnancy

Consult Your Doctor

Before beginning therapy with Zeroklot NXT 300mg Injection, tell your doctor if you are pregnant, suspect you are pregnant, or are planning to become pregnant. It is not known that Zeroklot NXT 300mg Injection interferes with pregnancy.

Breast Feeding-Consult Your Doctor

Breast Feeding

Consult Your Doctor

It is unknown if Zeroklot NXT 300mg Injection is excreted unaltered in breast milk. Please consult your doctor before breastfeeding. 

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

It is unknown whether Zeroklot NXT 300mg Injection is safe for patients with lung problems. Consult your doctor if you have lung disease before starting the treatment.

Liver-Consult Your Doctor

Liver

Consult Your Doctor

Inform your doctor if you have liver disease because of Zeroklot NXT 300mg Injection should be used cautiously with a liver condition.

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

It is unknown if consuming alcoholic beverages while taking Zeroklot NXT 300mg Injection is safe. Please consult with your physician.

Driving-Safe

Driving

Safe

It is safe to travel, drive a car, or operate heavy machinery after receiving Zeroklot NXT 300mg Injection. Zeroklot NXT 300mg Injection does not impair alertness or coordination.

Side Effects

Zeroklot NXT 300mg Injection 60mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Zeroklot NXT Injection side effects are

Serious side effects of Zeroklot NXT 300mg Injection are:

  • Severe allergic reactions (swelling of lips, tongue, or throat, difficulty breathing, or swallowing)

  • Too much bleeding (weakness, being pale, dizziness with headache, or unexplained swelling)

  • Blockage of blood vessels (pain, redness, or swelling in the legs, or coughing up blood)

  • Rash of dark red spots under the skin

Common side effects of Zeroklot NXT 300mg Injection are:

  • Bleeding

  • Bruising more easily

  • Low blood cell counts

  • Headache

  • Itchy red skin

  • Edema

  • Pain at the injection site

  • Pink patches on the skin

Expert Tips

  1. Zeroklot NXT 300mg Injection may cause bleeding, so get adequate rest, avoid sudden discontinuation, and apply a cool compress to ease injection-site discomfort.

  2. Avoid aspirin and NSAIDs unless approved by your doctor, as they can increase bleeding risk.

  3. Limit activities that increase the risk of injury or bleeding, such as contact sports.

  4. Consume Vitamin K rich foods in moderation and monitor your platelet count regularly to ensure safe treatment.

FAQs

Q1.

Who should not take Zeroklot NXT 300mg Injection?

Zeroklot NXT 300mg Injection is not recommended for people suffering from active major bleeding or a history of hypersensitivity to Zeroklot NXT 300mg Injection, heparin, Benzyl alcohol, or pork products. This drug is also not advised for people with a history of heparin-induced thrombocytopenia in the past hundred days.

Q2.

What should I not take with Zeroklot NXT 300mg Injection?

When taking Zeroklot NXT 300mg Injection, it's important to avoid certain medications, supplements, and activities that may increase the risk of bleeding or interact with the anticoagulant effects of Zeroklot NXT 300mg Injection includes other anticoagulants, non-steroidal anti-inflammatory drugs, and anti-platelets.

Q3.

What are the common side effects of Zeroklot NXT 300mg Injection?

Common side effects of Zeroklot NXT 300mg Injection may include bleeding or bruising at the injection site, nosebleeds, nausea, headache, and itching. Serious side effects such as severe bleeding or allergic reactions are rare but may occur.

Q4.

How long should Zeroklot NXT 300mg Injection treatment continue?

The duration of Zeroklot NXT 300mg Injection treatment depends on the underlying condition being treated, the risk of clotting, and individual patient factors. Treatment may be short-term (e.g., during hospitalisation or surgical procedures) or long-term for chronic conditions such as DVT or PE.

Q5.

When should you report to the doctor while using Zeroklot NXT 300mg Injection?

Contact your physician directly if you experience severe allergic reactions like the spelling of lips, tongue, throat, difficulty breathing or swallowing, unexplained swelling, painful Rash, chest pain, or blood in the cough during the treatment with Zeroklot NXT 300mg Injection.

Q6.

How should Zeroklot NXT 300mg Injection be stored?

Zeroklot NXT 300mg Injection should be stored at room temperature (between 68°F to 77°F or 20°C to 25°C) away from light and moisture. It should be kept out of the reach of children and not be frozen. Unused portions of Zeroklot NXT 300mg Injection solution should be discarded according to the manufacturer's instructions.

Fact Box

Molecule Name: 

Enoxaparin

Therapeutic class: 

Anticoagulant

Pharmacological class: 

Low molecular weight heparin (LMWH)

Indications: 

Treat and prevent blood clot

References

1. Rovi Pharma Industrial ServicesElectronic Medicines Compendium (EMC), [Revised on Apr 2022], [Accessed on March 2024],https://www.medicines.org.uk/emc/files/pil.9331.pdf 

2. Sanofi, [Revised on Apr 2022] [Accessed on March 2024], https://products.sanofi.us/lovenox/lovenox.pdf

3. Sanofi India Limited, Central Drugs Standard Control Organisation (CDSCO), [Revised on Dec 2018], [Accessed on March 2024], https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadPrescribingInfo/1CLEXANE-SANOFI.pdf 

4. KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Coagulation, Bleeding and Thrombosis, 8th Edition, 2019, 659-681.

5.https://www.ema.europa.eu/en/documents/product-information/inhixa-epar-product-information_en.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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Author Details
Dr. Vikas B S

Written By

Dr. Vikas B S

Pharm D

Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS

Last updated : 20 Jun 2026 | 06:03 AM (IST)

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