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Zybiraa 500mg Tablet
Last updated on 06 Jul 2026 | 10:57 AM (IST)
₹7589
MRP: ₹28106.2
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60 TABLET(s) IN A BOTTLE
Zybiraa 500 mg Tablet is a prescription anticancer medicine used in the treatment of prostate cancer in adult men. It contains abiraterone acetate, which works by reducing the production of androgens (male hormones) that promote the growth of prostate cancer cells. Zybiraa is taken under strict oncologist supervision, usually in combination with other medicines as part of a comprehensive treatment plan.
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Introduction to Zybiraa 500mg Tablet
Zybiraa 500mg Tablet contains the active constituent abiraterone acetate. It is used in adult men to treat prostate cancer, which has spread to other parts of the body. It is usually given with steroid medication to lower the chances of side effects. When Zybiraa 500mg Tablet is prescribed for an early stage of this disorder, it is used with testosterone lowering treatment.This medicine is not for use in women or children. Effective contraception must be taken throughout the treatment. This medicine contains lactose and sodium, inform your physician if you are lactose intolerant or on a salt control diet.
Inform to the physician if the patients have liver problems, high blood pressure, heart disorders, low blood potassium, diabetes, allergic conditions, or other diseases. Make sure to inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start the treatment with this medication. The most common side effects of this medication are fluid in feet or legs, high blood pressure, and diarrhea. A decrease in red blood cells and reduced sex drive may also occur with the intake of Zybiraa 500mg Tablet. This medicine should not be taken with Ra-223, which is used to treat prostate cancer.
Uses of Zybiraa 500mg Tablet
- Treatment of prostate cancer
Therapeutic Effects of Zybiraa 500mg Tablet
The drug works by inhibiting the production of hormone testosterone in the body. This can slow the growth of prostate cancer.
Interaction of Zybiraa 500mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Zybiraa 500mg Tablet and cause undesirable side effects.
More Information about Zybiraa 500mg Tablet
- This medicine does not require any particular storage condition.
- Keep out of sight and reach of children.
How to consume Zybiraa 500mg Tablet
The medicine should always be consumed as per the direction of your physician or pharmacist. The drug should be taken by mouth. It should not be taken with food. Swallow the tablets whole with water without breaking them. Food must be eaten at least 2 hours before taking the medication and must not be eaten for at least 1 hour after taking the medicine. Women who are pregnant or who may become pregnant should not touch this medication without gloves.
Safety Advice for Zybiraa 500mg Tablet
Breast Feeding
Zybiraa 500mg Tablet is not indicated to be used in breastfeeding women. Inform your doctor if you are breastfeeding before starting treatment with this medication.
Alcohol
It is not known whether it is safe to use this medication while consumption of alcohol. Consult the doctor before taking this medication.
Liver
Talk to your doctor if you have any liver diseases before taking Zybiraa 500mg Tablet, as this medication is contraindicated in patients with severe liver disorders.
Lungs
Talk to your doctor if you have any lung diseases before taking Zybiraa 500mg Tablet, as this medication is contraindicated in patients with severe lung disorders.
Driving
This medicine is not likely to affect driving and the use of any tools or machines.
Pregnancy
Zybiraa 500mg Tablet is not indicated to be used during pregnancy. Women who are pregnant or who may become pregnant should not touch this medication without gloves.
Side Effects of Zybiraa 500mg Tablet
Side effects are unwanted symptoms caused by medical treatment. Although all medicines can cause side effects, everyone will not get them.
Serious:
- Low blood potassium levels (muscle weakness, muscle twitches, or pounding heartbeat)
Common
- Fluid in legs or feet
- Low blood potassium
- High blood pressure
- Urinary tract infection
- Diarrhea
- High-fat levels in the blood
- Chest pain
- Irregular heartbeat
- Rapid heart rate
- Bone fracture
- Indigestion
- Blood in urine
- Rash
Word of Advice
Inform the doctor if the patient has any liver, blood pressure, heart disorders, diabetes and medication taken for different medical conditions before taking this medication. The medicine should be taken as prescribed by the doctor. This medication should be taken orally and it should be taken in an empty stomach. It should not be taken with food and swallow the tablet as a whole with water without breaking them. Food must be eaten at least 2 hours before taking the medication and the patient is advised to eat after 1hr after consuming the medication. Blood pressure, potassium levels, liver function tests should be monitored regularly while taking this medication.
FAQs about Zybiraa 500mg Tablet
Q1.
How to take an Zybiraa 500mg Tablet?
This medication should be taken as prescribed by the doctor and it should be taken in an empty stomach. Food must be eaten at least 2 hours before taking the medication and the patient is advised to eat after 1hr after consuming the medication.
Q2.
Can Zybiraa 500mg Tablet cure prostate cancer?
Abiraterone does not cure prostate cancer and it is used to treat prostate cancer which has spread to other parts of the body. It is usually given with steroid medication to lower the chances of side effects. This medication is prescribed at an early stage of the disorder and it is used along with testosterone lowering treatment.
Q3.
Can Zybiraa 500mg Tablet worsen liver diseases?
It is not recommended in the patients with severe liver conditions as it can worsen the situation. Inform the doctor if the patient has liver disorders before taking this medication.
Q4.
How do Zybiraa 500mg Tablet work?
Abiraterone Acetate is an anticancer medication. It works by preventing production of androgen and thereby inhibiting an enzyme responsible for the production of androgen.
Q5.
Is Zybiraa 500mg Tablet a chemotherapy drug?
No, it is not the chemotherapy drug and it is the hormonal treatment used to treat prostate cancer. It prevents the production of testosterone thereby reducing the growth of prostate cancer.
Fact Box of Zybiraa 500mg Tablet
Molecule name: Abiraternone actetate
| Therapeutic class: Antineoplastics |
Pharmacological class: Androstene derivatives
| Indications: Prostate cancer |
References
Centocor Ortho Biotech Inc, US Food and Drug Administration, [ Revised date: APR 2011] [ Accessed date: 26 MAY 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/202379lbl.pdf
Janssen- Cilag International NV, Electronics Medicine Compendium (emc), [Revised date: SEP 2021] [ Accessed date: 26 MAY 2022], https://www.medicines.org.uk/emc/files/pil.2381.pdf
Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Natural products in cancer chemotherapy: hormones and related agents, 12th edition, 2011, 1707 - 1709.
Disclaimer
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Author Details
Written By
Sakshi Anil More
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 06 Jul 2026 | 10:57 AM (IST)
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