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NP-Free Tablet
Salt Composition : Nortriptyline,pregabalin,methylcobalamin
Manufacturer : SYMBION LIFE SCIENCE
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Np-free Tablet
NP-Free Tablet contains an active component such as Nortriptyline, pregabalin, and methylcobalamin. Nortriptyline is an antidepressant medication that belongs to the class of drugs known as tricyclic antidepressants (TCAs). Pregabalin is an anticonvulsant and antiepileptic medication used to treat neuropathic pain, especially in conditions like diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. Methylcobalamin is a form of vitamin B12, an essential nutrient for the body. It is used as a dietary supplement to treat vitamin B12 deficiency, which can lead to anaemia and nervous system problems.
Individuals with known hypersensitivity or allergy to nortriptyline, pregabalin, methylcobalamin or other components of these medications should not take them. It is primarily eliminated through the kidneys. Therefore, individuals with severe renal impairment or end-stage renal disease should not use this medication. There is limited data on the safety of NP-Free tablets during pregnancy and breastfeeding. Pregnant or breastfeeding individuals should consult their healthcare provider before using this medication.
Uses of Np-free Tablet
NP-Free Tablet is used to treat the following:
- Neuropathic pain
Therapeutic Effects of Np-free Tablet
These medications prescribed by healthcare professionals in specific cases where the patient's medical condition requires multimodal treatment. For example, some individuals with neuropathic pain may benefit from a combination of nortriptyline and pregabalin as they work through different mechanisms to address pain and may have a synergistic effect. Nortriptyline works by affecting the levels of certain neurotransmitters in the brain, such as serotonin and norepinephrine, which play a role in regulating mood and pain perception. Pregabalin works by reducing the release of certain neurotransmitters in the brain, which helps to decrease pain signals and alleviate anxiety symptoms. Methylcobalamin can be added to support nerve health and potentially enhance the treatment outcomes.
Interaction of Np-free Tablet with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with NP-Free Tablet, reducing effectiveness by causing undesirable side effects.
More Information about Np-free Tablet
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Np-free Tablet
NP-Free Tablet can be administered orally in tablet form. The specific usage instructions may vary depending on the condition being treated, age, and the individual's weight. Oral tablets are typically taken with water, as directed by the healthcare provider.
Safety Advices for Np-free Tablet
Pregnancy
The safety of NP-Free Tablet during pregnancy has not been extensively studied, and limited information is available regarding its use in pregnant women. So it is advisable to consult a healthcare provider before using it.
Breast Feeding
The safety of NP-Free Tablet during breastfeeding has not been well studied, and limited information is available regarding its excretion into breast milk. As a result, it is recommended to exercise caution when using it while breastfeeding.
Lungs
Individuals with pre-existing lung conditions must inform their healthcare provider about their medical history before starting any new medication.
Liver
If you have a liver impairment or concerns about the safety of using NP-Free Tablets, discuss these with your healthcare provider. They can provide personalised guidance and ensure the most appropriate treatment plan for your medical condition.
Alcohol
NP-Free Tablet with alcohol can increase the risk of certain side effects and adverse reactions. It is generally recommended to avoid or limit alcohol consumption while taking these medications.
Driving
NP-Free Tablet can cause side effects that may impair driving abilities in some individuals. Therefore, caution is advised when operating a vehicle or performing any tasks that require alertness and concentration while taking these medications.
Side Effects of Np-free Tablet
NP-Free Tablet cause some side effects like all medications, although not everyone will experience them.
Serious side effects:
- Allergic reactions (e.g., rash, hives, difficulty breathing)
- Swelling of the hands, feet, or ankles
- Unusual bleeding or bruising
- Mood changes or depression
- Suicidal thoughts
- Irregular heartbeat
- Severe dizziness or fainting
Common side effects:
- Constipation
- Dry mouth
- Headache
- Feeling sleepy, tired or dizzy
- Diarrhoea
- Weight gain
- Blurred vision
Word of Advice
If you have prescribed NP-Free Tablet for neuropathic pain, follow your healthcare provider's instructions carefully. Monitor for unusual symptoms, such as mood changes and irregular heartbeat. If you experience any unusual or severe side effects while taking these medications, contact your doctor immediately. Pregnant or breastfeeding individuals should inform their obstetrician or healthcare provider before using this combination, as certain medications may not be safe during pregnancy or lactation. Regularly attend follow-up appointments and communicate openly with your healthcare provider about any concerns or questions for a successful and safe diabetes management journey.
FAQs
Q 1. What is the purpose of the combination of nortriptyline, pregabalin, and methylcobalamin?
This combination may be prescribed for individuals with certain medical conditions that require multimodal treatment. Nortriptyline is an antidepressant that may help with depression and neuropathic pain, while pregabalin is used to treat neuropathic pain and certain anxiety disorders. Methylcobalamin is a form of vitamin B12 that supports nerve health. The combination aims to address pain and neurological symptoms effectively.
Q 2. Are there any specific precautions or side effects associated with NP-Free Tablet
Yes, there may be specific precautions and side effects associated with NP-Free Tablet. Patients should consult their healthcare provider before starting this treatment to discuss individual health concerns, potential drug interactions, and any contraindications.
Q 3. Can I take this combination if I am pregnant or breastfeeding?
Pregnant or breastfeeding individuals should consult their healthcare provider before taking this medication. Some medications may be unsafe during pregnancy or breastfeeding, and alternative treatments may be considered.
Q 4. How should I take NP-Free Tablet?
Follow your doctor's instructions carefully regarding dosage, timing, and any specific recommendations for taking NP-Free Tablet. Never alter the prescribed dosages without consulting your healthcare provider.
Q 5. Is NP-Free Tablet addictive?
NP-Free Tablet has the potential for abuse and dependence, especially in individuals with a history of substance abuse.
Fact Box of Np-free Tablet
Molecule name: Nortriptyline, Pregabalin, Methylcobalamin
| Therapeutic class: Antidepressant and Anticonvulsive |
Pharmacological class: 1. Nortriptyline: Tricyclic antidepressants 2. Pregabalin: Anticonvulsant 3. Methylcobalamin: Vitamin B12 Supplement | Indications: Neuropathic pain |
References
- Ram Prabhoo et al., Efficacy and Tolerability of a Fixed Dose Combination of Methylcobalamin and Pregabalin in the Management of Painful Neuropathy, [Revised on 4/11/2012] [Accessed on 19/07/2023], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503385/
- Yasmin U Dongre et al., Sustained-release pregabalin with methylcobalamin in neuropathic pain: an Indian real-life experience [Revised on 19/5/2013] [Accessed on 19/07/2023], https://pubmed.ncbi.nlm.nih.gov/23761981/
Disclaimer
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