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Acotibien 100mg Tablet
Last updated on 24 Apr 2026 | 08:32 AM (IST)
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Introduction
Acotibien 100mg Tablet is a gastroprokinetic medication that belongs to a class of drugs known as prokinetic agents, containing the active ingredient Acotiamide. This medication is used to treat gastrointestinal conditions, primarily functional dyspepsia. Acotibien for functional dyspepsia helps relieve chronic or recurrent upper abdominal discomfort or pain, often accompanied by symptoms such as bloating, early satiety (feeling full quickly after eating), and nausea. It is especially useful in cases where no underlying structural or metabolic cause can be identified.
The Acotibien 100mg composition is designed to improve stomach motility and digestion, thereby easing symptoms. Many people also use Acotibien Tablet for indigestion and Acotibien 100mg for bloating to support digestive comfort.
Patients should follow the recommended Acotibien 100mg dosage as prescribed by their doctor. The medicine is generally well-tolerated, but medical advice is important before starting it.
If required, you can also find Acotibien 100mg substitute options prescribed by your healthcare provider. When comparing Acotibien 100mg vs Acotiamide, it’s important to note that Acotibien is a brand formulation of Acotiamide.
For convenience, you can buy Acotibien 100mg online after consulting your doctor and checking the Acotibien 100mg price at a trusted pharmacy.
Uses
Acotibien 100mg uses:
- Treatment of functional dyspepsia (indigestion).
How Acotibien 100mg Tablet works
Acotibien 100mg Tablet works by increasing the release of acetylcholine, a neurotransmitter that plays a role in stimulating the muscles of the gastrointestinal tract. This enhanced release of acetylcholine can help improve gastric emptying and reduce symptoms associated with functional dyspepsia, such as bloating and discomfort.
Interaction of Acotibien 100mg Tablet with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Acotibien 100mg Tablet and reduce effectiveness by causing undesirable side effects.
Storage conditions
- Store Acotibien 100mg Tablet at a temperature not exceeding (30°C).
- Do not freeze.
How to take Acotibien 100mg Tablet
Take the Acotibien 100mg Tablet as your physician advises. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Safety Advice for Acotibien 100mg Tablet
Breast Feeding
No clinical study was performed on the safety of Acotibien 100mg Tablet in breastfeeding women. Consult your doctor for more advice.
Alcohol
It is unknown whether consuming alcohol interacts with the Acotibien 100mg Tablet. Please consult your doctor for more advice.
Liver
It is unknown whether Acotibien 100mg Tablet can be used in patients with liver diseases. Consult your doctor for more advice.
Lungs
It is unknown whether Acotibien 100mg Tablet can be used in patients with lung diseases. Consult your doctor for more advice.
Driving
It is unknown whether Acotibien 100mg Tablet alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Pregnancy
There is no limited information on the safety of Acotibien 100mg Tablet during pregnancy. It is advised to consult your doctor if you are pregnant, suspect to be pregnant, or planning for pregnancy before taking this medicine.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Acotibien 100mg side effects are
Common
- Diarrhea
- Headache
- Dizzines
Expert tips
-
Diarrhea can cause dehydration and fluid loss.
-
Drink plenty of fluids such as water, oral rehydration solutions, or clear broths while using Acotibien 100mg Tablet.
-
Proper hydration helps replace lost fluids and electrolytes.
-
Staying hydrated supports the body’s recovery from diarrhea.
FAQs about Acotibien 100mg Tablet
Q1.
What is the mechanism of action of Acotibien 100mg Tablet in functional dyspepsia?
Acotibien 100mg Tablet is a prokinetic agent, which means it enhances the motility of the gastrointestinal tract. It does this by inhibiting the breakdown of acetylcholine, a neurotransmitter that stimulates the contraction of muscles in the digestive system. By increasing the levels of acetylcholine, this drug helps improve the movement of food through the stomach and small intestine, which can relieve symptoms of functional dyspepsia.
Q2.
Is Acotibien 100mg Tablet available over-the-counter (OTC)?
Acotibien 100mg Tablet is available by prescription and is not commonly found as an over-the-counter (OTC) medication. It is important to consult with a physician for an accurate diagnosis and prescription.
Q3.
Are there any side effects associated with Acotibien 100mg Tablet?
The common side effects of Acotibien 100mg Tablet may include headache, diarrhea, and dizziness. Not everyone will experience these side effects, and they are usually mild. If you experience severe side effects, contact your physician.
Q4.
Is Acotibien 100mg Tablet safe during pregnancy and breastfeeding?
The safety of Acotibien 100mg Tablet during pregnancy and breastfeeding has not been well studied. If you are pregnant, planning to become pregnant, or breastfeeding, it is highly advised to discuss the benefits and risks of using this drug with your physician before taking the medication.
Q5.
Can I take other medications with Acotibien 100mg Tablet?
Inform your physician about all the medications, supplements, and over-the-counter drugs you are taking, as there may be potential interactions with Acotibien 100mg Tablet. Your provider can assess the safety and efficacy of combining this drug with other medications and make appropriate recommendations.
Fact Box of Acotibien 100mg Tablet
|
Molecule name |
Acotiamide |
|
Therapeutic class |
Gastroprokinetics |
|
Pharmacological class |
Prokinetic agents |
|
Indications |
Treatment of functional dyspepsia (indigestion) |
References
Acofide Tablets 100 mg - Report on the deliberation results - PMDA. [Accessed date 02 Sep 2023]; https://www.pmda.go.jp/files/000153467.pdf
Masahiro Ueda et al; Profile of acotiamide in the treatment of functional dyspepsia; Clinical and Experimental Gastroenterology 2016; [Accessed date 02 Sep 2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4827886/
Jan Tack, Pieter Janssen; Acotiamide (Z-338, YM443), a new drug for the treatment of functional dyspepsia; Expert opinion on Investigational drugs 2011; [Accessed date 02 Sep 2023]; https://pubmed.ncbi.nlm.nih.gov/21417958/
Guoguang Xiao et al.; Efficacy and safety of acotiamide for the treatment of functional dyspepsia: systematic review and meta-analysis; The Scientific World Journal 2014; [Accessed date 02 Sep 2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4146483/
Kazuyoshi Yoshii et al.; Mechanism for distribution of acotiamide, a novel gastroprokinetic agent for the treatment of functional dyspepsia, in rat stomach; Journal of Pharmaceutical Sciences 2011;[Accessed date 02 Sep 2023]; https://pubmed.ncbi.nlm.nih.gov/21630282/
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. B. Deiva
Pharm D

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 24 Apr 2026 | 08:32 AM (IST)

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