Quick Summary
Acotrust Tablet
Last updated on 15 Apr 2026 | 12:21 PM (IST)
₹239
MRP: ₹298.36
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₹239
MRP: ₹298.36
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Introduction
Acotrust Tablet is a gastroprokinetic medication that belongs to a class of drugs known as the prokinetic agents containing the active ingredient Acotiamide. This medication is used to treat gastrointestinal conditions, primarily functional dyspepsia. Functional dyspepsia is a common digestive disorder caused by chronic or recurrent upper abdominal discomfort or pain, often accompanied by symptoms such as bloating, early satiety (feeling full quickly after eating), and nausea. It's a condition in which no underlying structural or metabolic cause can be identified.
Do not use this drug if you have a known allergy or sensitivity to it or any components in the medication. No clinical study was performed on the safety of Acotrust Tablet in breastfeeding and pregnant women. Consult your doctor for more advice. Individuals with severe kidney impairment may require adjusted dosages or closer monitoring when taking this drug. The safety and effectiveness of this medicine in children and infants have not been established. This medication is prescribed for adults, so its use in pediatric populations may require careful consideration and monitoring. Acotrust Tablet price varies by retailer and location.
Uses
Acotrust Tablet uses are:
Treatment of functional dyspepsia (indigestion).
How Acotrust Tablet Works
Acotiamide works by increasing the release of acetylcholine, a neurotransmitter that plays a role in stimulating the muscles of the gastrointestinal tract. This enhanced release of acetylcholine can help improve gastric emptying and reduce symptoms associated with functional dyspepsia, such as bloating and discomfort.
Interaction of Acotrust Tablet with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Acotrust Tablet and reduce effectiveness by causing undesirable side effects.
Storage Conditions
Store the Acotrust Tablet at a temperature not exceeding (30°C).
Do not freeze.
How to take Acotrust Tablet
Take the Acotrust Tablet as your physician advises. Do not crush, chew, or open the medicine. Your physician will decide the correct Acotrust tablet dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Safety Advice for Acotrust Tablet
Breast Feeding
No clinical study was performed on the safety of Acotrust Tablet in breastfeeding women. Consult your doctor for more advice.
Alcohol
It is unknown whether consuming alcohol interacts with the Acotrust Tablet. Please consult your doctor for more advice.
Liver
It is unknown whether Acotrust Tablet can be used in patients with liver diseases. Consult your doctor for more advice.
Lungs
It is unknown whether Acotrust Tablet can be used in patients with lung diseases. Consult your doctor for more advice.
Driving
It is unknown whether the Acotrust Tablet alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Pregnancy
There is no limited information on the safety of Acotrust Tablet during pregnancy. It is advised to consult your doctor if you are pregnant, suspect to be pregnant, or planning for pregnancy before taking this medicine.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
Diarrhea
Headache
Dizziness
Expert tips
Stay Hydrated: Diarrhea can cause dehydration and fluid loss, so it is important to drink plenty of fluids like water, oral rehydration solutions, or clear broths.
Support Recovery with Acotrust Tablet: Proper hydration while using Acotrust Tablet helps replace lost fluids and electrolytes, aiding the body’s recovery.
FAQs about Acotrust Tablet
Q1.
How does Acotrust Tablet work to treat functional dyspepsia?
Acotrust Tablet is a prokinetic agent, which means it enhances the motility of the gastrointestinal tract. It does this by inhibiting the breakdown of acetylcholine, a neurotransmitter that stimulates the contraction of muscles in the digestive system. By increasing the levels of acetylcholine, this drug helps improve the movement of food through the stomach and small intestine, which can relieve symptoms of functional dyspepsia.
Q2.
Is Acotrust Tablet available over-the-counter (OTC)?
Acotrust Tablet is available by prescription and is not commonly found as an over-the-counter (OTC) medication. It is important to consult with a physician for an accurate diagnosis and prescription.
Q3.
Are there any side effects associated with Acotrust Tablet?
The common side effects of Acotrust Tablet may include headache, diarrhoea, and dizziness. Not everyone will experience these side effects, and they are usually mild. If you experience severe side effects, contact your physician.
Q4.
Is Acotrust Tablet safe during pregnancy and breastfeeding?
The safety of Acotrust Tablet during pregnancy and breastfeeding has not been well studied. If you are pregnant, planning to become pregnant, or breastfeeding, it is highly advised to discuss the benefits and risks of using this drug with your physician before taking the medication.
Q5.
Can I take other medications with an Acotrust Tablet?
Inform your physician about all the medications, supplements, and over-the-counter drugs you are taking, as there may be potential interactions with Acotrust Tablet. Your provider can assess the safety and efficacy of combining this drug with other medications and make appropriate recommendations.
Fact Box
Molecule name: | Acotiamide |
Therapeutic class: | Gastroprokinetics |
Pharmacological class: | Prokinetic agents |
Indications: | Treatment of functional dyspepsia (indigestion) |
References
Acofide Tablets 100 mg - Report on the deliberation results - PMDA. [Accessed date 02 Sep 2023]; https://www.pmda.go.jp/files/000153467.pdf
Masahiro Ueda et al; Profile of acotiamide in the treatment of functional dyspepsia; Clinical and Experimental Gastroenterology 2016; [Accessed date 02 Sep 2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4827886/
Jan Tack, Pieter Janssen; Acotiamide (Z-338, YM443), a new drug for the treatment of functional dyspepsia; Expert opinion on Investigational drugs 2011; [Accessed date 02 Sep 2023]; https://pubmed.ncbi.nlm.nih.gov/21417958/
Guoguang Xiao et al.; Efficacy and safety of acotiamide for the treatment of functional dyspepsia: systematic review and meta-analysis; The Scientific World Journal 2014; [Accessed date 02 Sep 2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4146483/
Kazuyoshi Yoshii et al.; Mechanism for distribution of acotiamide, a novel gastroprokinetic agent for the treatment of functional dyspepsia, in rat stomach; Journal of Pharmaceutical Sciences 2011;[Accessed date 02 Sep 2023]; https://pubmed.ncbi.nlm.nih.gov/21630282/
Disclaimer
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Author Details
Written By
Dr. Deva Prasath S.
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 15 Apr 2026 | 12:21 PM (IST)
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