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Alpostadil 500mcg Injection
Last updated on 04 Jun 2026 | 07:41 AM (IST)
₹5349
MRP: ₹6523.65
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Alpostadil 500mcg Injection
Salt Composition
ALPROSTADILMarketer
QUESTUS PHARMA PRIVATE LIMITED
Prepaid Only. Non-Returnable.
18% OFF
₹5349
MRP: ₹6,523.65
Inclusive of all taxes
18% Off
Salt Composition
ALPROSTADILMarketer
QUESTUS PHARMA PRIVATE LIMITED
Prepaid Only. Non-Returnable.
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Introduction
Alpostadil 500mcg Injection, also referred to as alpostadil injection or alprostadil medicine, contains the active component Alprostadil. It is commonly prescribed for erectile dysfunction (ED) in men who have difficulty achieving or maintaining an erection. If you are wondering what is alprostadil injection used for, it works by improving blood flow to specific areas of the body. The key alprostadil injection uses include treating ED, improving circulation in peripheral arterial disease (PAD), and managing certain congenital heart conditions like patent ductus arteriosus (PDA) in newborns.
This medication may also be used in diagnostic procedures, such as penile Doppler ultrasound, to assess blood flow and erectile function. The alprostadil use depends on the condition being treated and should always be guided by a healthcare professional.
Understanding how to use alprostadil injection is essential for safe and effective treatment. Typically, alprostadil injection how to use involves administration under medical supervision, either directly into the penile tissue, as a urethral application, or through other prescribed methods depending on the indication. Patients should never attempt to self-administer without proper training. Always follow your doctor’s instructions on how to use alprostadil correctly.
Individuals with a known allergy or hypersensitivity to alpostadil 500mcg injection or any of its components should not use this medication. It should be avoided in men with penile implants or conditions that make injections unsafe, such as penile fibrosis, curvature, or a history of priapism (prolonged erection). It is also not recommended for individuals with conditions that increase the risk of priapism, such as sickle cell anemia, multiple myeloma, or leukemia.
Patients with bleeding disorders or those taking anticoagulants should use alpostadil injection cautiously, as it may increase the risk of bleeding at the injection site. It should not be used along with alpha-blocker medications, as this may lead to severe low blood pressure. In infants with certain congenital heart defects, use should be carefully evaluated by a specialist. Elderly patients can use this medicine, but caution is advised.
Like all medications, there may be alpostadil injection side effects, including pain at the injection site, prolonged erection, or low blood pressure, which should be reported to a doctor immediately.
Patients often ask where can I get alprostadil. It is a prescription medicine and should be purchased only from licensed pharmacies or trusted medical platforms. Cost-related factors such as the alpostadil 500 mcg price may vary depending on availability, location, and supplier.
Uses
Alpostadil 500mcg Injection is used for the following:
Erectile dysfunction (ED)
Peripheral arterial disease (PAD)
Patent ductus arteriosus (PDA) in Infants
Diagnostic testing
How Alpostadil 500mcg Injection works
Alpostadil 500mcg Injection binds to specific receptors on smooth muscle cells in blood vessels and tissues. When it binds to these receptors, it triggers biochemical events that lead to vasodilation. It relaxes the smooth muscles in blood vessel walls, particularly in the penis, when used for erectile dysfunction. It involves promoting the relaxation of smooth muscle cells and improving blood flow to specific body areas, depending on its intended use.
Interaction of Alpostadil 500mcg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Alpostadil 500mcg Injection, reducing effectiveness by causing undesirable side effects.
Storage conditions
Store at room temperature below 20 to 25°C
Keep away from moisture, heat, and light.
It should not be frozen.
Keep away from children and pets.
How to use Alpostadil 500mcg Injection
Alpostadil 500mcg Injection can be administered via various routes, depending on the medical condition. For erectile dysfunction (ED), it can be injected directly into the penis (intracavernosal injection), applied topically to the penile tip (urethral application), or used as a urethral suppository.
Safety advice
Pregnancy
If you are pregnant or trying to become pregnant, it is important to talk to your doctor before taking Alpostadil 500mcg Injection.
Breast Feeding
There is limited research on the safety of Alpostadil 500mcg Injection in breastfeeding women. It is important to talk to your doctor before taking this medication.
Lungs
If you have lung disease, talking to your doctor before taking Alpostadil 500mcg Injection is important.
Liver
Alpostadil 500mcg Injection is metabolized in the liver, so individuals with severe liver disease may require dose adjustments. Patients with liver problems should discuss their condition with their healthcare provider before using it.
Alcohol
It is unsafe to drink alcohol while taking Alpostadil 500mcg Injection. Excessive alcohol consumption can increase the risk of certain side effects.
Driving
Alpostadil 500mcg Injection can cause dizziness or fainting, especially if low blood pressure occurs. If you experience any side effects, consult your healthcare provider before taking it while driving.
Side Effects
Alpostadil 500mcg Injection causes some side effects like all medications, although not everyone will experience them.
Serious:
Priapism
Penile fibrosis
Allergic reactions
Low blood pressure
Cardiovascular effects
Bleeding
Common:
Pain or discomfort
Penile burning or tingling
Urethral irritation
Headache
Flushing
Flu-like symptoms
Expert Tips
Use Alprostadil 500 mcg Injection only under medical supervision to determine the correct dose and method of administration.
Watch for priapism (prolonged erection) and seek immediate medical help if it occurs.
Inform your healthcare provider about any existing conditions, such as:
Bleeding disorders
Heart conditions
Liver disease
Dose adjustments or special precautions may be required based on your health condition.
Use with caution if you have penile abnormalities or a predisposition to priapism.
Monitor its use carefully in infants, weighing the benefits against potential risks.
FAQs
Q1.
What is the risk of priapism with Alpostadil 500mcg Injection?
Alpostadil, a prolonged and painful erection, is a potential side effect of Alpostadil 500mcg Injection. It is a serious condition and requires immediate medical attention.
Q2.
Can women use Alpostadil 500mcg Injection?
Alpostadil 500mcg Injection is primarily used in men, but some applications exist for women, such as treating sexual arousal disorders or facilitating certain medical procedures. Its use in women should be discussed with a healthcare provider.
Q3.
Can I use Alpostadil 500mcg Injection for recreational purposes or to enhance sexual performance?
Alpostadil 500mcg Injection is a prescription medication and should only be used under medical supervision for legitimate medical reasons. Its recreational use is not recommended and can be dangerous.
Q4.
How long can I safely use Alpostadil 500mcg Injection for ED?
Your healthcare provider should determine the duration of treatment with Alpostadil 500 mcg Injection for ED. Long-term use should be monitored for potential side effects.
Q5.
Can I adjust the dosage of Alpostadil 500mcg Injection on my own?
Do not adjust the dosage of Alpostadil 500mcg Injection without consulting your healthcare provider. They will determine the appropriate dosage based on your condition.
Q6.
What are the common side effects of Alpostadil 500mcg Injection?
Common side effects of Alpostadil 500mcg Injection may include pain or discomfort at the injection site (for intracavernosal injections), penile burning or tingling (for topical or urethral forms), headache, flushing, and flu-like symptoms.
Fact Box
Molecule name | Alprostadil |
Therapeutic class | Vasodilator |
Pharmacological class | Prostaglandin E1 (PGE1) Analog |
Indications | 1. Erectile dysfunction (ED) 2. Peripheral arterial disease (PAD) 3. Patent Ductus Arteriosus (PDA) in Infants 4. Diagnostic testing |
References
Pfizer Limited, Electronic Medicines Compendium (EMC), [Revised on Apr 2021] [Accessed on 3rd Oct 2023], https://www.medicines.org.uk/emc/files/pil.1092.pdf
John Hwa, Kathleen Martin, The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 321-338.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. Vikas B S
Pharm D

Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 04 Jun 2026 | 07:41 AM (IST)

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