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PROSTAL 500MCG INJECTION_1
PROSTAL 500MCG INJECTION_2
PROSTAL 500MCG INJECTION_1
60% Off

Prostal 500mcg Injection

Prescription Required

cold-chain

Salt Composition : Alprostadil

Manufacturer : CELON LABORATORIES LTD

Origin of Medicine : India

MRP: ₹6411
Price : ₹2564
You Save : ₹3847 (60%)

1 Vial(s)

Prepaid Only. Non-Returnable


Introduction to Prostal 500mcg Injection

Prostal 500mcg injection contains active components called Alprostadil. This medication is often used to treat ED in men with difficulty achieving or maintaining an erection. It may be used to improve blood flow in patients with peripheral arterial disease (PAD), a condition in which blood flow to the extremities (usually the legs) is reduced. In newborns with certain heart conditions, such as PDA, it can open a blood vessel called the ductus arteriosus. It can also be used in diagnostic tests to assess blood flow in specific body areas, such as during penile Doppler ultrasound studies to evaluate erectile function.

Individuals who have a known allergy or hypersensitivity to Alprostadil or any of its components should not use the medication. It should be avoided in men with penile implants or conditions that make penile injections unsafe, such as penile fibrosis, curvature, or priapism (prolonged erections). It should not be used in individuals with conditions predisposing them to priapism, such as sickle cell anemia, multiple myeloma, or leukemia. It should not be used in individuals who experience unexplained genital or pelvic pain, as it may indicate an underlying medical condition.

Individuals with bleeding disorders or those taking anticoagulant medications (blood thinners) should use Prostal 500mcg injection cautiously, as it may increase the risk of bleeding at the injection site. It should not be used concomitantly with alpha-blocker medications used to treat conditions like benign prostatic hyperplasia (BPH) and high blood pressure, as it can lead to severe low blood pressure. It should not be used in infants with congenital heart defects who have conditions that are worsened by increased blood flow to the lungs. It can be used in elderly patients, but caution may be required.


Uses of Prostal 500mcg Injection

  • Erectile dysfunction (ED)
  • Peripheral arterial disease (PAD)
  • Patent ductus arteriosus (PDA) in Infants
  • Diagnostic testing

Therapeutic Effects of Prostal 500mcg Injection

Prostal 500mcg injection binds to specific receptors on smooth muscle cells in blood vessels and various tissues. When it binds to these receptors, it triggers biochemical events that lead to vasodilation. It relaxes the smooth muscles in blood vessel walls, particularly in the penis, when used for erectile dysfunction. It involves promoting the relaxation of smooth muscle cells, improving blood flow to specific body areas, depending on its intended use.


Interaction of Prostal 500mcg Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Prostal 500mcg injection, reducing effectiveness by causing undesirable side effects.


More Information about Prostal 500mcg Injection

  • Store at room temperature below 20 to 25°C
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Prostal 500mcg Injection

Prostal 500mcg injection can be administered via various routes, depending on the medical condition. For erectile dysfunction (ED), it can be injected directly into the penis (intracavernosal injection), applied topically to the penile tip (urethral application), or used as a urethral suppository.


Safety Advices for Prostal 500mcg Injection

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Pregnancy

  

If you are pregnant or trying to become pregnant, it is important to talk to your doctor before taking Prostal 500mcg injection.

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Breast Feeding

  

There is limited research on the safety of  Prostal 500mcg injection in breastfeeding women. It is important to talk to your doctor before taking this medication.

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Lungs

  

If you have lung diseases, talking to your doctor before taking Prostal 500mcg injection is important.

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Liver

  

Prostal 500mcg injection is metabolized in the liver, so individuals with severe liver disease may require dose adjustments. Patients with liver problems should discuss their condition with their healthcare provider before using it.

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Alcohol

  

It is unsafe to drink alcohol while taking Prostal 500mcg injection. Excessive alcohol consumption can increase the risk of certain side effects.

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Driving

  

Prostal 500mcg injection can cause dizziness or fainting, especially if low blood pressure occurs. If you experience any side effects, consult your healthcare provider before taking it while driving.


Side Effects of Prostal 500mcg Injection

Prostal 500mcg injection causes some side effects like all medications, although not everyone will experience them. 

Serious:

  • Priapism
  • Penile fibrosis
  • Allergic reactions
  • Low blood pressure
  • Cardiovascular effects
  • Bleeding

Common:

  • Pain or discomfort
  • Penile burning or tingling
  • Urethral irritation
  • Headache
  • Flushing
  • Flu-like symptoms

Word of Advice

Use Prostal 500mcg injection under medical supervision to determine the right dose and method. Watch for priapism (prolonged erection) and seek immediate help if it occurs. Inform your healthcare provider of any underlying medical conditions, such as bleeding disorders, heart conditions, or liver disease, as dose adjustments or special precautions may be necessary. Be cautious with penile abnormalities or predisposition to priapism. Monitor the use of this medication in infants and consider benefits versus risks. Avoid it if you are allergic to it or its components. Use alcohol with caution, and be aware of medication interactions. Assess how this medication affects you before driving or operating machinery. Discuss its use during pregnancy and breastfeeding with your healthcare provider. Follow storage instructions for safe and effective use.


FAQs

Q 1. What is the risk of priapism with Prostal 500mcg injection?

Priapism, a prolonged and painful erection, is a potential side effect of Prostal 500mcg injection. It is a serious condition and requires immediate medical attention.

Q 2. Can women use Prostal 500mcg injection?

Prostal 500mcg injection is primarily used in men, but some applications exist for women, such as treating sexual arousal disorders or facilitating certain medical procedures. Its use in women should be discussed with a healthcare provider.

Q 3. Can I use Prostal 500mcg injection for recreational purposes or to enhance sexual performance?

Prostal 500mcg injection is a prescription medication and should only be used under medical supervision for legitimate medical reasons. Its recreational use is not recommended and can be dangerous.

Q 4. How long can I safely use Prostal 500mcg injection for ED?

Your healthcare provider should determine the duration of Prostal 500mcg injection use for ED. Long-term use should be monitored for potential side effects.

Q 5. Can I adjust the dosage of Prostal 500mcg injection on my own?

Do not adjust the dosage of Prostal 500mcg injection without consulting your healthcare provider. They will determine the appropriate dosage based on your condition.

Q 6. What are the common side effects of Prostal 500mcg injection?

Common side effects of Prostal 500mcg injection may include pain or discomfort at the injection site (for intracavernosal injections), penile burning or tingling (for topical or urethral forms), headache, flushing, and flu-like symptoms.


Fact Box of Prostal 500mcg Injection

Molecule name: Alprostadil

Therapeutic class: Vasodilator

Pharmacological class: Prostaglandin E1 (PGE1) Analogue

Indications: 

1. Erectile dysfunction (ED)

2. Peripheral arterial disease (PAD)

3. Patent ductus arteriosus (PDA) in Infants

4. Diagnostic testing


References

  1. Pfizer Limited, Electronic Medicines Compendium (EMC), [Revised on Apr 2021] [Accessed on 3rd Oct 2023], https://www.medicines.org.uk/emc/files/pil.1092.pdf
  2. John Hwa, Kathleen Martin, The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 321-338.

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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