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LUPRODEX DEPOT 11.25MG INJECTION
Salt Composition : Leuprolide Acetate
Manufacturer : BHARAT SERUMS & VACCINES LTD
Origin of Medicine : India
1 Vial(s) Of 2ml
Introduction to Luprodex Depot 11.25mg Injection
Luprodex Depot 11.25mg injection consists of the active ingredient Leuprolide. It belongs to the class of medicines called Gonadotropin Releasing Hormone (GnRH) agonists. This injection treats prostate cancer in men, hormone-responsive breast cancer, and endometriosis (tissue that usually lines the interior of the uterus grows outside of it), and uterine fibroids (noncancerous growths of the uterus) in women. This medicine is also used in treating premature puberty (central precocious puberty); due to certain hormonal releases, a child’s body begins to change into an adult at an early age.
Do not receive this injection if you are allergic to Luprodex Depot 11.25mg or any other ingredients, including Goserelin and Triptorlin of the medicine. Before receiving this medicine, inform your physician if you have a liver or kidney impairment. , Inform your doctor if you have undiagnosed abnormal uterine bleeding. Do not take this treatment if you are pregnant or planning to get pregnant. During the treatment, the existing symptoms may worsen due to the sex steroid increase in the body. Talk to your physician for more concerns. Report to your doctor if your child has a progressive brain tumor.
Before starting the treatment, notify your doctor about your underlying medical conditions, such as diabetes, seizures, heart problems with chest pain, irregular heartbeats, depression, or are at increased risk of thinning of bones (osteoporosis). This medicine is not recommended in pregnant and breastfeeding women and patients with abnormal vaginal bleeding. If you are a woman of childbearing age, use non-hormonal contraceptives while taking Luprodex Depot 11.25mg injection. Report to your doctor if you are a man with urinary obstruction or had an operation to remove your testicles. Tell your doctor if you feel pressure on the spinal cord and experience urinary disorders and haematuria (blood in the urine).
Uses of Luprodex Depot 11.25mg Injection
- Prostate cancer
- Hormone-responsive breast cancer in perimenopausal (around menopause) women
- Endometriosis (a painful illness in which the tissue that normally lines the inside of the uterus grows outside of your uterus)
- Central precocious puberty (a child’s body begins to change into an adult too soon caused by a release of certain hormones)
Therapeutic Effects of Luprodex Depot 11.25mg Injection
Luprodex Depot 11.25mg decreases testosterone or estrogen production, depending on the treated condition. This helps to slow the growth of cancer cells, reduce the size of uterine fibroids, and alleviate the symptoms of endometriosis and early onset of puberty.
Interaction of Luprodex Depot 11.25mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications such as Quinidine, Procainamide, Amiodarone, Sotalol, Pain killers, and Antibiotics may interact with the effects of Luprodex Depot 11.25mg and reduce its effectiveness by causing undesirable side effects.
More Information about Luprodex Depot 11.25mg Injection
- Keep Luprodex Depot 11.25mg out of sight and reach of children.
- Store in a cool, dry place, away from direct heat and light.
- Store below 25oC
- Do not refrigerate or freeze.
How to consume Luprodex Depot 11.25mg Injection
Luprodex Depot 11.25mg injection is usually administered in the arm, thigh or abdomen. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advices for Luprodex Depot 11.25mg Injection
It is unsafe to use Luprodex Depot 11.25mg injection because it is contraindicated in pregnant women. Tell your doctor if you are pregnant or planning to get pregnant before taking this treatment.
Luprodex Depot 11.25mg injection is contraindicated in breastfeeding women. Inform your doctor if you are breastfeeding before taking this injection.
Inform your doctor if you experience any pulmonary embolism, shortness or difficulty of breath, or other underlying lung conditions; consult your doctor for more information.
Luprodex Depot 11.25mg should be used cautiously in patients with liver impairment. Consult your doctor before receiving it. Notify your doctor about underlying liver conditions.
Consuming alcohol during the Luprodex Depot 11.25mg injection treatment may increase the risk of thinning bones (osteoporosis). Hence caution should be taken. Consult your doctor for more information
Luprodex Depot 11.25mg Injection can cause drowsiness, visual disturbances, or dizziness. It is unsafe; hence avoid driving if you are unwell.
Side Effects of Luprodex Depot 11.25mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Severe rash, itching
- Shortness or difficulty of breath
- Cough with blood
- Pulmonary embolism
- Severe headache
- Altered blood sugar and cholesterol levels
- Injection site reactions
- Loss of appetite
- Abnormal liver function
- Swelling in the ankle or hand
- Difficulty sleeping, headache
- Mood swings, depression
- Weight changes
- Nausea, vomiting
- Vaginal dryness, bleeding
- Loss of interest in sexual intercourse
- Hot flushes
- Bone pain, muscle weakness
- Breast tenderness
Word of Advice
During the treatment of breast cancer, regular checkup of every three months during the treatment with the combinations of an aromatase inhibitor. Do not receive this injection if you experience any abnormal vaginal bleeding. Consult your doctor immediately if you or your child is suffering from a headache even after treating it with pain killer, vision problems, buzzing, or ringing in the ear. If you have diabetes, ask your doctor to monitor your glucose and blood sugar levels regularly. Before starting, inform your doctor if you are still mensurating.
Q 1. How does Luprodex Depot 11.25mg work? Luprodex Depot 11.25mg decreases testosterone or estrogen production, depending on the treated condition. This helps to slow the growth of cancer cells, reduce the size of uterine fibroids, and alleviate the symptoms of endometriosis and early onset of puberty.Who should not use Luprodex Depot 11.25mg?Luprodex Depot 11.25mg should not be used by pregnant and breastfeeding women, people who are allergic to the medication, or people with a history of osteoporosis or bone fractures. It should also be used cautiously in people with a past of depression or mental illness.What should I do if I miss a dose of Luprodex Depot 11.25mg? If you miss a dose of Luprodex Depot 11.25mg, contact your healthcare provider as soon as possible to schedule the missed dose. Do not double up on doses to make up for a missed one.Can Luprodex Depot 11.25 mg cause weight gain? Weight gain is not a common side effect of Luprodex Depot 11.25mg, but it may occur in some people.How does Luprodex Depot 11.25mg help with endometriosis? Endometriosis is a condition where the tissue that lines the uterus grows outside of it, which can cause pain and other symptoms. Luprodex Depot 11.25mg decreases estrogen production, contributing to endometriosis tissue growth. By reducing estrogen levels, Leuprolide can help alleviate the symptoms of endometriosis.
Fact Box of Luprodex Depot 11.25mg Injection
Molecule name: Leuprolide
Therapeutic class: Antineoplastics
Pharmacological class: Gonadotropin-Releasing Hormone (GnRH) agonists
1. Prostate cancer
2. Hormone-responsive breast cancer in perimenopausal (around menopause) women
3. Endometriosis (a painful illness in which the tissue that normally lines the inside of the uterus grows outside of your uterus)
4. Central precocious puberty (a child’s body begins to change into an adult too soon caused by a release of certain hormones)
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Introduction to Endocrinology: The hypothalamic-pituitary axis, 12th edition, 2011, 1122.
- KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormones, 7th edition, 2013, 243.
- Takeda UK Limited, Electronic medicines compendium (emc), [ Revised on June 2022] [ Accessed on 12th April 2023], https://www.medicines.org.uk/emc/product/4651/smpc
- Abbott Laboratories, US Food and Drug Administration, [Issued on Feb 2016] [ Accessed on 12th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020517s036_019732s041lbl.pdf
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