• Rheumatoid arthritis
• Polyarticular juvenile idiopathic arthritis
• Enthesitis-related arthritis
• Ankylosing spondylitis
• Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis
• Psoriatic arthritis
• Plaque psoriasis
• Hidradenitis suppurativa
• Crohn’s disease
• Ulcerative colitis
• Non-infectious uveitis

Mabvinra 40mg Injection restricts TNF-alpha's ability to connect with its receptors, which in turn prevents TNF-alpha from mediating downstream signaling pathways. The inflammatory response, which includes immune cell activation, inflammatory cytokine generation, and recruitment of inflammatory cells to inflammatory areas, is largely regulated by these signaling pathways.  By restricting the signaling pathway it decreases inflammation in various autoimmune diseases. 

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Mabvinra 40mg Injection and reduce effectiveness by causing undesirable side effects. Live vaccines must not be concurrently used along with Mabvinra 40mg Injection. 

• Store in a refrigerator (2°C – 8°C).
• Do not freeze.
• Protect the medicine from light and excessive moisture.
• Keep the medicine out of reach of children and pets
• It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.

Mabvinra 40mg Injection is administered by injection under the skin (subcutaneously). The dosage and frequency of Mabvinra 40mg Injection will depend on various factors, including the patient's age, weight, overall health, and the type and stage of disease being treated. It's important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first. This medicine is to be administered by injection under the skin (subcutaneously). Your doctor or other healthcare professional will train you on how to use this injection. Do not self-administer this injection until you get trained. 

If a dose is missed, it should be taken as soon as possible unless it's within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped and the regular dosing schedule resumed. It's important not to take a double dose of Mabvinra 40mg Injection to make up for a missed dose.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common: 

• Injection site reactions
• Rash
• Headache
• Sinusitis
• Upper respiratory infections
• Fever

Serious 

• Heart problems
• Abnormal heart beat
• Severe skin reactions
• GI bleeding
• Abnormal blood count values
• Liver injury
• Bone problems
• Infections
• Severe respiratory problems

If you have prescribed Mabvinra 40mg Injection or any other medication, it is important to follow the instructions provided by your healthcare provider and to report any side effects or concerns promptly. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Mabvinra 40mg Injection. It is recommended to monitor your blood counts at regular intervals. Include anti-inflammatory foods in your diet, such as olive oil, nuts, seeds, fruits, vegetables, and fatty fish.

Include foods like avocados, almonds, seeds, and olive oil in your diet as sources of healthful fats. These fats can improve general health by lowering inflammation. To stay hydrated, sip lots of water throughout the day.  

Consult your physician before getting any vaccinations because certain of them can make you sick and should not be administered while you are on this medication. If you currently have or have ever had hepatitis B, let your doctor know as this medication may make the illness more likely to recur. One may receive instruction on administering medication at home. Before administering an injection to yourself, be sure you understand all the instructions. Every time you give yourself a shot, use a new part of your body. Make sure you rotate body parts by keeping track of where you administer each shot. Injecting into areas of skin that are hard, tender, bruised, or red is not advised.

Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately. 

1. Amgen Limited, Electronics Medicines Compendium(emc), [ Revised on February 2023] [ Accessed on 27-03-2024], https://www.medicines.org.uk/emc/files/pil.9546.pdf

2. AbbVie Inc,  United States Food and Drug Administration (US FDA), [ Revised on November 2023] [Accessed on 27-03-2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/125057s423lbl.pdf

3. AbbVie Inc, [Revised on February 2024], [Accessed on 27-03-2024],  https://www.rxabbvie.com/pdf/humira.pdf