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Myo-Pyrolate Injection
Prescription Required
Salt Composition : Glycopyrrolate,neostigmine Methylsulphate
Manufacturer : NEON LABORATORIES LTD
Origin of Medicine : India
1 Ampoule(s) Of 5ml
Introduction to Myo-pyrolate Injection
Myo-pyrolate injection contains two active ingredients, glycopyrronium, and neostigmine, which belong to the anticholinergics and cholinesterase inhibitors groups, respectively. The drug has effectively reversed the action of certain muscle relaxants used in the surgery.Â
Inform your doctor if you have a heart or kidney problem before taking the medicine. Consult your doctor if you are allergic to sodium or glycopyrronium, and neostigmine or any of the ingredients in them. Discuss your prescribed and non-prescribed medicine and your previous health history with your doctor; it will be helpful for them to treat you based on your condition. Children and elderly patients should be cautious while taking this medicine. Consult your doctor if you are planning to get pregnant or think you may be pregnant while breastfeeding.
Uses of Myo-pyrolate Injection
- Reversal of muscle relaxation
Therapeutic Effects of Myo-pyrolate Injection
Neostigmine inhibits the enzyme acetylcholinesterase to increase the availability of acetylcholine at the motor endplate. This has an antagonizing effect on the non-depolarising nerve and muscular blockade. Glycopyrrolate counteracts the undesirable effects caused by neostigmine by blocking the action of acetylcholine present in nerves and smooth muscles. This combination reverses the muscle relaxation produced by medications that relax muscles.
Interaction of Myo-pyrolate Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with myo-pyrolate injection, reducing effectiveness by causing undesirable side effects.
More Information about Myo-pyrolate Injection
- Store at room temperature, between 25°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Myo-pyrolate Injection
Myo-pyrolate injection is administered intravenously, infusing it into a vein. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Safety Advices for Myo-pyrolate Injection
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Pregnancy
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There is not enough reliable information to know if myo-pyrolate injection is safe to take during pregnancy or breastfeeding. Therefore, you must talk to your doctor before taking this medication if you are pregnant.
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Breast Feeding
 ÂMyo-pyrolate injection should only be used during breastfeeding only if considered necessary by your doctor. Always consult a healthcare provider before taking this medication while breastfeeding.
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Lungs
  Myo-pyrolate injection have not been specifically studied in patients with lung disease. However, you must consult your healthcare provider before taking this medication if you have lung disease.
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Liver
  It is unknown whether myo-pyrolate injection is safe for patients with liver problems. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
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Alcohol
 ÂIt is unknown whether myo-pyrolate injection is safe to consume alcohol under medication. So, it is recommended to consult your doctor before taking medicine.
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Driving
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Myo-pyrolate injection can cause side effects such as weakening of eyesight. It is not safe to take this medication while driving or handling heavy machines.
Side Effects of Myo-pyrolate Injection
Myo-pyrolate injection cause some side effects like all medications, although not everyone will experience them.Â
Serious
- Allergic reactions (Swelling of the face, lips, or throat, difficulty in breathing, rash, itching, hives, and dizziness)
Common
- Dry mouth
- Constipation
- Slow heart rate (Bradycardia)
- Irregular heartbeat
- Difficulty urination
- Frequent urination
- Visual disturbances
- Sensitive light (Photophobia)
- Glaucoma (increased pressure in the eye)
- Absence of sweating
- Skin dryness
- Reddening of the skin
- Confusion
- Nausea (feeling sick)
- Vomiting (being sick), dizziness
- Increased secretions of the stomach
- Increased mucus secretion
- Too much saliva
- Stomach cramps
- Diarrhea
Word of Advice
Drink plenty of water and take electrolytes to tackle the water loss caused by the drug. It is recommended to avoid chunk food, which leads to constipation. Eat a healthy diet which are rich in fiber content. This medicine is usually given after surgery to reverse the effect of muscle relaxants. It is recommended to get enough rest to achieve a speedy recovery.
FAQs
Q 1. Can I take myo-pyrolate injection if I am allergic to sodium?
Consult your doctor if you are allergic to sodium before using the myo-pyrolate injection. Because it contains sodium as one of the ingredients in them.
Q 2. Can I experience constipation during the myo-pyrolate injection medication?
Yes, you may experience constipation as an adverse effect of the medication. It is recommended to avoid chunk food, which leads to constipation. Eat a healthy diet that is rich in fiber content.
Q 3. Can I drive while taking the myo-pyrolate injection?
Myo-pyrolate injection can cause side effects such as weakening of eyesight. It is not safe to take this medication while driving or handling heavy machines.
Q 4. Is there any information I need to tell my doctor before taking the myo-pyrolate injection?
Inform your doctor if you have high cholesterol levels, lung, liver, kidney, and heart problems, diabetes, and blood disorders before starting the medicine.
Fact Box of Myo-pyrolate Injection
Molecule name: Glycopyrronium + neostigmine | Therapeutic class: Nerve blocker |
Pharmacological class:Â 1. Glycopyrronium-Anticholinergics 2. Neostigmine-Cholinesterase inhibitors | Indications: Reversal of muscle relaxation |
References
- B. Braun Melsungen AG, Electronic Medicines Compendium (EMC), [Revised on April 2019] [Accessed on 29th Dec 2023], https://www.medicines.org.uk/emc/files/pil.6599.pdf
- Marieke Kruidering-Hall, Lundy Campbell, Skeletal Muscle Relaxants, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 474-491.
Disclaimer
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