Orgonist 120 mg Uses :

• Advanced hormone-sensitive prostate cancer

Orgonist 120mg tablet can competitively bind to pituitary GnRH receptors, thereby reducing the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which results in a reduction of testosterone levels in men with prostate cancer.

Taking Orgonist 120mg Tablet with any of the following medicines can change the effect of either of them and may increase the risk of side effects.

Cyclosporine (Oral Route) Life-threatening
Do not take together.
Concomitant use may reduce the absorption of cyclosporine and decrease its effectiveness, increasing the risk of organ rejection.

Warfarin or other oral anticoagulants (Oral Route) Life-threatening
Use only under strict medical supervision.
Orlistat may reduce vitamin K absorption and increase the risk of bleeding.

Levothyroxine (Oral Route) Moderate
Do not take at the same time.
Orlistat may reduce the absorption of levothyroxine and affect thyroid hormone control. A time gap of at least 4 hours is usually recommended.

Amiodarone (Oral Route) Moderate
Use with caution.
Orlistat may reduce the absorption of amiodarone and decrease its effectiveness.

Antiepileptic medicines such as Valproate, Lamotrigine, or Carbamazepine (Oral Route) Moderate
Use under medical supervision.
Orlistat may reduce the absorption of these medicines and increase the risk of seizures.

• Store below 25°C.

• Protect from light.

• Keep children away from the sight and reach of this medication.

Take the Orgonist 120mg tablet as your physician advises. Usually, the tablets will be taken with or without food. Do not crush, chew, or open the medicine. Your physician will decide the correct orgonist 120 mg dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop. If any side effects are seen it will be orgonist 120 mg substitute provided by a physician.

Organist 120 mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common

• Hot flushes

• Increased blood sugar levels

• Increased blood fat (triglyceride) levels

• Muscle and joint pain

• Decreased blood hemoglobin levels

• Increased liver enzymes

• Tiredness

• Constipation

• Diarrhea

• Dizziness

• Headache

• Nausea

• Rash

• Fatigue

• low red cell count (anemia)

• Breast enlargement in men (gynecomastia)

• Sleeplessness

• Depression

• High blood pressure

• Increased sweating

• Decreased interest in sex

• Increased weight

• Inform your doctor if you have any liver problems or are planning a liver function test, as the medicine may affect the results.

• Drink plenty of water and take electrolytes to replace fluid loss during diarrhoea.

• Avoid junk food and eat fibre-rich foods to help manage constipation.

• Get adequate rest to reduce muscle pain, joint pain, and tiredness.

• Your doctor may monitor treatment progress with a PSA test.

• Regularly check your blood pressure and blood glucose levels while on the medication.

1. Accord Healthcare Polska Sp.z o.o., European Medicines Agency (EMA), [Revised on April 2022], [Accessed 06 Mar 2024], https://www.ema.europa.eu/en/documents/product-information/orgovyx-epar-product-information_en.pdf
2. Bushu Pharmaceuticals Ltd, Electronic medicines compendium (emc), [Revised on Dec 2020], [ Accessed 06 Mar 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/214621s000lbl.pdf