-
Avoid grapefruit and its juice as well as any preparations containing St. John’s wort during Palbace 75mg treatment.
-
Use effective birth control:
-
Females: During treatment and for at least 3 weeks after the final dose
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Males: During treatment and for at least 14 weeks after the final dose
-
-
Palbace 75mg may reduce fertility; discuss potential risks with your doctor if you're planning to have children.
-
Your doctor may recommend regular blood tests to monitor if the medication affects your blood cell counts.
Sourced from:Manufacturer Authorized Distributor
Quick Summary
Palbace 75mg Tablet
Written By:Sakshi Anil MoreB. Pharm Reviewed By:Dr. Tejashwin AdigaMBBS
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹16875
MRP: ₹21093.75
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21 TABLET(s) IN A BOX
Sourced from:Manufacturer Authorized Distributor
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Introduction
Palbace 75mg Tablet contains the active ingredient palbociclib, a cyclin-dependent kinase (CDK) inhibitor used in targeted cancer therapy. It is prescribed to treat hormone receptor-positive, HER2-negative advanced or metastatic breast cancer, often in combination with other anticancer medications like letrozole or fulvestrant. Palbace (Palbociclib) works by slowing down the growth of cancer cells and preventing them from multiplying uncontrollably.
The Palbace Palbociclib dosage is determined by your oncologist based on your individual treatment plan. It is usually taken once daily for 21 days followed by a 7-day break, completing a 28-day cycle. Always follow your doctor’s instructions carefully when taking Palbace. During treatment, regular monitoring of your blood cell counts is recommended to avoid complications.
Common Palbace 75 mg side effects include nausea, vomiting, tiredness, diarrhea, loss of appetite, hair thinning, dry skin, mouth sores, taste changes, blurred vision, and low white or red blood cell counts. If any of these effects persist or worsen, inform your healthcare provider.
The Palbace 75 mg price may vary by brand and location. For patients in India, the Palbace Palbociclib cost can be high due to import and specialty pharmacy sourcing. Prices may differ between generic and branded versions, so it’s best to consult a verified oncology pharmacy for accurate and up-to-date pricing.
Uses
Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How Palbace 75mg Tablet works
Palbace 75mg Tablet works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
Interaction of Palbace 75mg Tablet with other drugs
Inform your doctor about all medications including prescribed, over-the-counter, nutritional or vitamin supplements and herbal products that you are taking or have taken before the treatment. Concurrent use of palbociclib with CYP3A4 inhibitors such as fentanyl has reported increased fentanyl toxicity. certain medications may interact with the effectiveness of this drug.
Storage conditions
- Keep Palbace 75mg Tablet out of sight and reach of children.
- Store at 20°C to 25°C
How to take Palbace 75mg Tablet
Take Palbace 75mg Tablet exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.
Safety Advice for Palbace 75mg Tablet
Breast Feeding
Unsafe
It is not recommended to take Palbace 75mg tablet while breastfeeding as it is not known whether it passes into the breast milk.
Alcohol
Consult Your Doctor
It is unknown whether it is safe to drink alcohol while taking Palbace 75 mg. Check with your doctor for advice.
Liver
Consult Your Doctor
Inform your physician if you have any liver disorders before taking Palbace 75 mg, as it should be used with caution in liver disorder patients.
Lungs
Driving
Consult Your Doctor
Palbace 75mg tablet can cause tiredness. Avoid driving if you are unwell.
Pregnancy
Unsafe
It is not recommended to take Palbace 75mg tablet during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Side Effects
Palbace side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
- Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
- Lung inflammation (chest pain, dry cough, or difficulty breathing)
Common:
- Tiredness
- Hair loss
- Dry skin, rash
- Infections
- Low blood cell counts
- Decreased of appetite
- Nausea, vomiting
- Diarrhea
- Swelling of lips and mouth
- Changes in taste
- Nose bleed
- Dry eye, blurred vision, increased tearing
Expert Tips
FAQs about Palbace 75mg Tablet
Q1.
Is Palbace 75mg Tablet targeted therapy?
Yes, Palbace 75mg Tablet is a targeted therapy. This medication belongs to the class of cyclin-dependent kinase inhibitors.
Q2.
Can children use Palbace 75 mg?
No, Palbace 75mg tablet is not recommended for adolescents and children under 18.
Q3.
Does Palbace 75mg Tablet affect fertility?
Yes, Palbace 75mg Tablet may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.
Fact Box of Palbace 75mg Tablet
|
Molecule name |
Palbociclib |
|
Therapeutic class |
Cyclin-dependent kinase inhibitor |
|
Pharmacological class |
Anticancer agents |
|
Indications |
HR-positive, HER2-negative advanced or metastatic breast cancer |
References
- Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
- Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
- Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
Disclaimer
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Author Details
Written By
Sakshi Anil More
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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