Semaneo 0.5mg Pen Injection is used to:

• Improve blood sugar control in adults with type 2 diabetes mellitus.

• Support diabetes management along with a suitable diet and regular physical activity.

• Be used alone when metformin is considered inappropriate because of intolerance or contraindications.

• Be used with other medicines for diabetes when additional blood sugar control is required.

Semaglutide works by mimicking the action of GLP-1, a naturally occurring hormone involved in blood glucose regulation. It increases insulin release when blood glucose levels are elevated and reduces glucagon secretion. It also slows gastric emptying, which can affect the rate at which glucose enters the bloodstream.

Tell your doctor about all the medicines you take before using Semaneo 0.5mg Pen Injection.

• Insulin and sulfonylureas: Using semaglutide with insulin or a sulfonylurea may increase the risk of hypoglycaemia. Your doctor may need to adjust the dose of the other medicine.

• Other semaglutide-containing medicines: Do not use Semaneo with another medicine containing semaglutide unless specifically advised by your doctor.

• Other GLP-1 receptor agonists: Combining semaglutide with another GLP-1 receptor agonist is not recommended.

• Oral medicines: Semaglutide delays gastric emptying and may affect the absorption of some medicines taken by mouth. Tell your doctor about all oral medicines you use.

• Store Semaneo 0.5mg Pen Injection in a refrigerator at 2°C to 8°C.

• Do not freeze the medicine.

• Keep it away from the cooling element of the refrigerator.

• Protect the pen from light by keeping the pen cap on when it is not in use.

• Keep it out of the reach of children.

For storage after first use, follow the instructions supplied with the specific Semaneo pen presentation.

Semaneo 0.5mg Pen Injection is administered under the skin once a week. It can be injected into the abdomen, thigh or upper arm. It may be administered at any time of day, with or without food. Try to use it on the same day each week.

Semaglutide treatment is generally started at a lower dose and increased gradually. The 0.5mg dose is typically reached after at least four weeks on the 0.25mg once-weekly dose. Your doctor will determine the appropriate dose and duration of treatment. 

Inspect the solution before use. It should be clear and colourless. Do not use the medicine if you notice particles or an unusual change in appearance.

Common side effects of semaglutide include:

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Abdominal pain

These effects may be more noticeable when treatment is started or the dose is increased and may improve as your body adjusts to the medicine.

Contact your doctor if you experience severe or persistent abdominal pain, repeated vomiting, symptoms of dehydration, changes in vision or symptoms of a serious allergic reaction. Semaglutide can also be associated with pancreatitis, gallbladder problems and diabetic retinopathy complications.

• Use Semaneo exactly as prescribed by your doctor.

• Take your weekly dose on the same day each week.

• Do not increase or decrease the dose without medical advice.

• Follow the diet and physical activity plan recommended for your diabetes.

• Eating smaller meals may help if you experience nausea or early fullness.

• Drink enough fluids, particularly if vomiting or diarrhoea occurs.

• Monitor your blood glucose as advised by your doctor.

• If you use insulin or a sulfonylurea, ask your doctor how often you should monitor your blood sugar.

• Tell your healthcare team that you use semaglutide before surgery or deep sedation.

• Do not share your injection pen with another person.