Semawin 0.5mg Pen Injection is used to:

• Manage obesity in eligible adults as part of a weight-management plan.

• Manage overweight in adults who have a weight-related health condition.

• Support weight loss and long-term weight maintenance when combined with diet and physical activity.

• Support appetite control by reducing hunger and increasing feelings of fullness.

The 0.5 mg strength is generally used after the initial 0.25 mg dose when dose escalation is prescribed.

Semawin contains Semaglutide, which acts similarly to the natural hormone GLP-1. It activates GLP-1 receptors involved in appetite regulation and glucose control.

Semaglutide increases insulin release when blood glucose levels are high and reduces glucagon release. It also slows gastric emptying and increases feelings of fullness. These effects can reduce hunger and food intake and support weight management.

Tell your doctor about all medicines, supplements and herbal products you take.

• Insulin or sulfonylureas: May increase the risk of low blood sugar when used with Semaglutide.

• Other Semaglutide-containing medicines: Do not combine them unless specifically prescribed.

• Other GLP-1 receptor agonists: Do not use them together unless advised by your doctor.

• Oral medicines: Delayed gastric emptying may affect the absorption of some medicines taken by mouth.

• Store in a refrigerator at 2°C to 8°C.

• Do not freeze the pen.

• Do not use the pen if it has been frozen.

• Protect it from direct light.

• Keep it out of the reach of children.

• Follow the product-specific instructions supplied with the pen after first use.

Use Semawin exactly as prescribed.

The 0.5 mg dose is injected under the skin once a week. It can be given at any time of the day, with or without food.

• Inject into the abdomen, thigh or upper arm.

• Rotate injection sites.

• Do not inject into a vein or muscle.

• Use a new needle for every injection.

• Do not share the pen or needles.

• Do not increase the dose without medical advice.

The Semawin 0.5 mg pen contains 2 mg/1.5 mL, providing four 0.5 mg doses.

Common side effects include:

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Abdominal pain

• Bloating

• Indigestion

• Headache

• Dizziness

• Decreased appetite

These effects are often more noticeable when the dose is increased and may improve as the body adjusts.

Serious Side Effects

Seek medical attention for severe persistent abdominal pain, severe allergic reactions, persistent vomiting or diarrhoea, gallbladder problems, changes in vision, or symptoms of low blood sugar.

• Use Semawin on the same day each week.

• Follow the dose-escalation schedule prescribed by your doctor.

• Do not increase or decrease the dose yourself.

• Eat smaller meals if nausea occurs.

• Drink enough fluids.

• Rotate injection sites.

• Use a new needle for every injection.

• Tell your doctor before surgery or deep sedation.

• Seek medical attention for severe persistent abdominal pain.