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Prevents rejection of kidney transplant
Sporadic lymphangioleiomyomatosis (lung disease)

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Siromus 1mg Tablet is an immunosuppressant that decreases the activity of your body’s immune system and prevents it from attacking the transplanted organ.

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Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Siromus 1mg tablet and decrease its effectiveness by causing undesirable side effects.

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Keep Siromus 1mg Tablet out of sight and reach of children.
Do not store above 25°C.

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Always take Siromus 1mg Tablet exactly as your physician has told you. Swallow the tablet whole with water. Do not crush or chew the tablets. This medicine must be consistently taken, either with or without food. Avoid drinking grapefruit juice and eating grapefruits while taking this medication.

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Do not breastfeed while taking Siromus 1mg Tablet. You need to tell your doctor if you are breastfeeding before taking this medicine.

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It is unknown whether consuming alcohol while taking a Siromus 1mg tablet is safe. Please speak with your physician.

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Inform your doctor if you have any history of liver transplantation before starting treatment with the Siromus 1mg tablet. Because it is not recommended to use in such conditions, and medication should be used cautiously in liver disease patients.

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Inform your doctor if you have any history of lung transplantation before starting treatment with the Siromus 1mg tablet. Because it is not recommended to use it in such conditions, and medication should be used with caution in lung disease patients.

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Taking a Siromus 1mg tablet will not impact the body. Talk with your doctor for more information.

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Siromus 1mg Tablet may harm your unborn baby. You need to inform your doctor if you are pregnant or planning to get pregnant before taking this medicine. Use effective birth control during the treatment and for at least twelve months after the last dose.

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Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

Severe allergic reactions (swelling of face, tongue, or mouth, difficulty in breathing)
Low blood cell counts with kidney damage (haemolytic uraemic syndrome)
Infections

Common

Headache
Fever, pain
High blood pressure and cholesterol levels
Constipation, diarrhea, stomach pain
Nausea
Rash
Infrequent, absent, or heave periods
Rapid heart rate
High blood sugar
Joint pain
Acne
Swelling of the body,including feet and hands

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Inform your doctor if you have a history of lung or liver transplantation or hypersensitivity. If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Avoid live vaccines during the treatment with Siromus 1mg Tablet. Notify your doctor immediately if you took any. Use effective birth control during the treatment for at least twelve months, even after the last dose. This medicine can increase the risk of skin cancer, so use sunscreen protection.

"}},{"id":"7c0fed56-1659-4fbb-b4c4-f881d1687464","type":"FAQ","position":10,"content_placement":2,"data":{"heading":"FAQs about Siromus 1mg Tablet","faq_list":[{"id":"8607a7cd-3d65-4bc2-a3da-22331c1a25cd","question":"

Will Siromus 1mg Tablet affect fertility?

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Siromus 1mg Tablet can decrease the sperm count, which returns to the normal state after the treatment. For more fertility concerns, talk with your doctor.

"},{"id":"18efc65a-26d7-451b-b1b6-f1feeef4adeb","question":"

Can Siromus 1mg Tablet cause any injury to the kidney?

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Siromus 1mg can damage the kidney with or without rashes (haemolytic uraemic syndrome). Talk with your doctor before starting this medicine.

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What should I be aware of before taking Siromus 1mg Tablet?

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If you are intolerant to some sugar like lactose and sucrose, inform your doctor before the treatment. And, Siromus 1mg Tablet shouldn’t be taken with grapefruit or its juice.

"},{"id":"2ec12a7b-dc80-49c1-b078-bae3c2f28ebe","question":"

Can Siromus 1mg Tablet, cause diabetics?

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Blood sugar levels may be affected by Siromus 1mg Tablet. So, regularly check your blood sugar levels, and notify your doctor if any sudden changes.

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What should I inform my doctor before starting the Siromus 1mg Tablet treatment?

","answer":"

Inform your doctor if you have any history of lung or liver transplantation and hypersensitivity because Siromus 1mg Tablet is not recommended in such cases.

"}]}},{"id":"3d1600e9-e159-48a3-b5b1-5dbff9701327","type":"PARA","position":11,"content_placement":3,"data":{"heading":"Fact Box of Siromus 1mg Tablet","text":"

Molecule name: Sirolimus

Therapeutic class: Antineoplastics

Pharmacological class: Immunosuppressants

Indications:

1. Prevent rejection of kidney transplant

2. Sporadic lymphangioleiomyomatosis (lung disease)

"}},{"id":"580b9d77-0fbb-462d-acf9-05f7589041f3","type":"PARA","position":12,"content_placement":3,"data":{"heading":"References","text":"

Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Targeted therapies: Tyrosine kinase inhibitors, monoclonal antibodies, and cytokines, 12th edition, 2011, 1735.
Pfizer Limited, Electronic medicines compendium (emc), [ Revised on July 2021] [ Accessed on 08th March 2023], https://www.medicines.org.uk/emc/files/pil.1368.pdf
Pfizer Limited, [ Revised on August 2023] [ Accessed on 08th March 2023],https://labeling.pfizer.com/showlabeling.aspx?id=139.

"}},{"id":"4b92f54f-a552-4188-97ab-dce84aba6083","type":"DISCLAIMER","position":13,"content_placement":5,"data":{"heading":"Disclaimer","text":"

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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