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Siropan 1mg Tablet
Last updated on 12 Aug 2026 | 06:37 AM (IST)
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Introduction to Siropan 1mg Tablet
Siropan 1mg Tablet is an immunosuppressant medication containing the active ingredient called Sirolimus. It helps prevent organ rejection in people who had a kidney transplant in combination with other medications. Following an organ transplant, our body’s immune system will try to reject the new organ. This medication controls the body’s immune response to accept the transplanted organ.
It also treats a rare lung disorder called S-LAM (sporadic lymphangioleiomyomatosis). The most common symptom of this disease is shortness of breath. Before taking this medication, you need to talk to your physician if you have liver disorders, intolerance to some sugars, a family history of skin cancer, high cholesterol, or other diseases. Siropan 1mg Tablet is not recommended for adolescents and children under 18 years of age.
Avoid drinking grapefruit juice and eating grapefruits while taking this medication. Limit exposure to the sun while taking this medication. Use sunscreen with high SPF (sun protection factor) and wear protective clothing when you go outside. Avoid live vaccines during the treatment with Siropan 1mg Tablet. Use effective birth control during the treatment and for at least twelve months after the last dose.
Uses of Siropan 1mg Tablet
- Prevents rejection of kidney transplant
- Sporadic lymphangioleiomyomatosis (lung disease)
Therapeutic Effects of Siropan 1mg Tablet
Siropan 1mg tablet is an immunosuppressant that decreases the activity of your body’s immune system and prevents it from attacking the transplanted organ.
Interaction of Siropan 1mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Siropan 1mg tablet and decrease its effectiveness by causing undesirable side effects.
More Information about Siropan 1mg Tablet
- Keep Siropan 1mg tablet out of sight and reach of children.
- Do not store above 25°C.
How to consume Siropan 1mg Tablet
Always take Siropan 1mg tablet exactly as your physician has told you. Swallow the tablet whole with water. Do not crush or chew the tablets. This medicine must be consistently taken, either with or without food. Avoid drinking grapefruit juice and eating grapefruits while taking this medication.
Safety Advice for Siropan 1mg Tablet
Breast Feeding
Do not breastfeed while taking Siropan 1mg tablet. You need to tell your doctor if you are breastfeeding before taking this medicine.
Alcohol
It is unknown whether consuming alcohol while taking a Siropan 1mg tablet is safe. Please speak with your physician.
Liver
Inform your doctor if you have any history of liver transplantation before starting treatment with the Siropan 1mg tablet. Because it is not recommended to use in such conditions, and medication should be used cautiously in liver disease patients.
Lungs
Inform your doctor if you have any history of lung transplantation before starting treatment with the Siropan 1mg tablet. Because it is not recommended to use it in such conditions, and medication should be used with caution in lung disease patients.
Driving
Taking a Siropan 1mg tablet will not impact the body. Talk with your doctor for more information.
Pregnancy
Siropan 1mg tablet may harm your unborn baby. You need to inform your doctor if you are pregnant or planning to get pregnant before taking this medicine. Use effective birth control during the treatment and for at least twelve months after the last dose.
Side Effects of Siropan 1mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (swelling of face, tongue, or mouth, difficulty in breathing)
- Low blood cell counts with kidney damage (haemolytic uraemic syndrome)
- Infections
Common
- Headache
- Fever, pain
- High blood pressure and cholesterol levels
- Constipation, diarrhea, stomach pain
- Nausea
- Rash
- Infrequent, absent, or heave periods
- Rapid heart rate
- High blood sugar
- Joint pain
- Acne
- Swelling of the body including feet and hands.
Word of Advice
Inform your doctor if you have a history of lung or liver transplantation, hypersensitivity. If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Avoid live vaccines during the treatment with Siropan 1mg tablet. Notify your doctor immediately if you took any. Use effective birth control during the treatment for at least twelve months, even after the last dose. This medicine can increase the risk of skin cancer, so use sunscreen protection.
FAQs about Siropan 1mg Tablet
Q1.
Will Siropan 1mg tablet affect fertility?
Siropan 1mg tablet can decrease the sperm count, which returns to the normal state after the treatment. For more fertility concerns, talk with your doctor.
Q2.
Can Siropan 1mg tablet cause any injury to the kidney?
Siropan 1mg tablet can damage the kidney with or without rashes (haemolytic uraemic syndrome). Talk with your doctor before starting this medicine.
Q3.
What should I be aware of before taking Siropan 1mg tablet?
If you are intolerant to some sugar like lactose and sucrose, inform your doctor before the treatment. And, Siropan 1mg tablet shouldn’t be taken with grapefruit or its juice.
Q4.
Can Siropan 1mg tablet cause diabetics?
Blood sugar levels may be affected by Siropan 1mg tablet. So, regularly check your blood sugar levels, and notify your doctor of any sudden changes.
Q5.
What should I inform my doctor before starting the Siropan 1mg tablet treatment?
Inform your doctor if you have any history of lung or liver transplantation and hypersensitivity because Siropan 1mg tablet is not recommended in such cases.
Fact Box of Siropan 1mg Tablet
Molecule name: Sirolimus
| Therapeutic class: Antineoplastics |
Pharmacological class: Immunosuppressants | Indications: 1. Prevents rejection of kidney transplant 2. Sporadic lymphangioleiomyomatosis (lung disease) |
References
- Targeted therapies: Tyrosine kinase inhibitors, monoclonal antibodies, and cytokines, 12th edition, 2011, 1735.
- Pfizer Limited, Electronic medicines compendium (emc), [ Revised on July 2021] [ 08th March 2023] https://www.medicines.org.uk/emc/files/pil.1368.pdf
- Pfizer Limited, [ Revised on August 2023] [ Accessed on 08th March 2023],https://labeling.pfizer.com/showlabeling.aspx?id=139.
Disclaimer
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Author Details
Written By
Guruvigneshwari M.
M. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 12 Aug 2026 | 06:37 AM (IST)
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